ClinVar Miner

Variants studied for Multiple myeloma

Coded as:
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Gene type:
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If a variant has more than one submission, it may be counted in more than one significance column. If this is the case, the total number of variants will be less than the sum of the other cells.

pathogenic likely pathogenic uncertain significance likely benign benign total
5 190 1 0 0 195

Gene and significance breakdown #

Total genes and gene combinations: 59
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Gene or gene combination pathogenic likely pathogenic uncertain significance total
TP53 1 65 0 66
BRAF 0 20 0 20
NRAS 0 14 0 14
HRAS, LRRC56 0 13 0 13
B2M 0 5 0 5
IDH1 0 5 0 5
KRAS 1 4 0 5
CDK4 0 4 0 4
PTPN11 0 4 0 4
FGFR3 3 1 0 3
IDH2 0 3 0 3
PIK3CA 0 3 0 3
FAT1 0 2 0 2
KMT2C 0 2 0 2
TET2 0 2 0 2
ARID4A 0 1 0 1
ATM 0 1 0 1
AURKA 0 1 0 1
BAP1 0 1 0 1
BARD1 0 1 0 1
BCORL1 0 1 0 1
BRCA2 0 1 0 1
CDKN2C 0 1 0 1
CRBN, TRNT1 0 1 0 1
CREBBP 0 1 0 1
CYLD 0 1 0 1
DIS3 0 1 0 1
DNMT3A 0 1 0 1
EIF1AX 0 1 0 1
ERF 0 1 0 1
FLT3 0 1 0 1
H1-4 0 1 0 1
H2AC16 0 1 0 1
H2AC17 0 1 0 1
H3C1 0 1 0 1
HDAC4 0 1 0 1
IL7R 0 1 0 1
KDM5C, LOC130068308 0 1 0 1
KMT2D 0 1 0 1
LATS1 0 1 0 1
LIG4 0 0 1 1
LOC130063979, PIK3R2 0 1 0 1
MGA 0 1 0 1
MST1R 0 1 0 1
MYD88 0 1 0 1
NCOR2 0 1 0 1
NF1 0 1 0 1
NKX2-1, SFTA3 0 1 0 1
P2RY8 0 1 0 1
PIK3R2 0 1 0 1
RECQL4 0 1 0 1
RXRA 0 1 0 1
SAMHD1 0 1 0 1
SGK1 0 1 0 1
SH2B3 0 1 0 1
TCF3 0 1 0 1
TET3 0 1 0 1
TRAF5 0 1 0 1
YAP1 0 1 0 1

Submitter and significance breakdown #

Total submitters: 5
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Submitter pathogenic likely pathogenic uncertain significance total
Database of Curated Mutations (DoCM) 0 139 0 139
Xiao lab, Department of Pathology, Memorial Sloan Kettering Cancer Center 1 52 0 53
OMIM 3 0 0 3
Biotechnology, Institute of Science, Nirma University 1 1 0 2
Baylor Genetics 0 0 1 1

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