If a variant has more than one submission, it may be counted in more than one significance column. If this is the
case, the total number of variants will be less than the sum of the other cells.
pathogenic |
likely pathogenic |
uncertain significance |
likely benign |
benign |
not provided |
total |
10
|
12
|
572
|
220
|
1393
|
4
|
2196
|
Gene and significance breakdown #
Total genes and gene combinations: 21
Gene or gene combination |
pathogenic |
likely pathogenic |
uncertain significance |
likely benign |
benign |
not provided |
total |
TTN
|
10
|
10
|
506
|
200
|
1214
|
4
|
1933
|
LOC126806425, TTN
|
0 |
1
|
7
|
3
|
18
|
0 |
28
|
LOC101927055, TTN
|
0 |
1
|
4
|
1
|
20
|
0 |
26
|
LOC126806430, TTN
|
0 |
0 |
6
|
4
|
16
|
0 |
26
|
LOC126806422, TTN
|
0 |
0 |
5
|
1
|
15
|
0 |
19
|
LOC126806420, TTN
|
0 |
0 |
5
|
2
|
10
|
0 |
17
|
LOC126806424, TTN
|
0 |
0 |
4
|
1
|
12
|
0 |
17
|
LOC126806423, TTN
|
0 |
0 |
3
|
2
|
11
|
0 |
16
|
LOC126806421, TTN
|
0 |
0 |
3
|
0 |
12
|
0 |
15
|
LOC126806427, TTN
|
0 |
0 |
2
|
0 |
13
|
0 |
15
|
LOC126806431, TTN
|
0 |
0 |
5
|
0 |
9
|
0 |
14
|
LOC126806426, TTN
|
0 |
0 |
6
|
1
|
6
|
0 |
13
|
LOC126806429, TTN
|
0 |
0 |
1
|
1
|
10
|
0 |
12
|
LOC129935183, TTN
|
0 |
0 |
3
|
2
|
7
|
0 |
12
|
LOC126806428, TTN
|
0 |
0 |
1
|
0 |
10
|
0 |
11
|
LOC126806433, TTN
|
0 |
0 |
7
|
0 |
4
|
0 |
11
|
LOC129935184, TTN
|
0 |
0 |
2
|
1
|
4
|
0 |
6
|
LOC129935182, TTN
|
0 |
0 |
1
|
0 |
1
|
0 |
2
|
LOC126806432, TTN
|
0 |
0 |
1
|
0 |
0 |
0 |
1
|
LOC129935185, TTN
|
0 |
0 |
0 |
0 |
1
|
0 |
1
|
LOC129935186, TTN
|
0 |
0 |
0 |
1
|
0 |
0 |
1
|
Submitter and significance breakdown #
Submitter |
pathogenic |
likely pathogenic |
uncertain significance |
likely benign |
benign |
not provided |
total |
Illumina Laboratory Services, Illumina
|
0 |
1
|
514
|
219
|
1081
|
0 |
1815
|
Genome-Nilou Lab
|
0 |
0 |
0 |
0 |
635
|
0 |
635
|
Baylor Genetics
|
1
|
6
|
51
|
0 |
0 |
0 |
58
|
GeneReviews
|
5
|
0 |
1
|
0 |
0 |
2
|
8
|
OMIM
|
2
|
0 |
0 |
0 |
0 |
0 |
2
|
Centogene AG - the Rare Disease Company
|
0 |
1
|
1
|
0 |
0 |
0 |
2
|
Intergen, Intergen Genetics and Rare Diseases Diagnosis Center
|
0 |
0 |
1
|
1
|
0 |
0 |
2
|
NeuroMeGen, Hospital Clinico Santiago de Compostela
|
0 |
2
|
0 |
0 |
0 |
0 |
2
|
GenomeConnect, ClinGen
|
0 |
0 |
0 |
0 |
0 |
2
|
2
|
Johns Hopkins Genomics, Johns Hopkins University
|
1
|
1
|
0 |
0 |
0 |
0 |
2
|
MGZ Medical Genetics Center
|
0 |
0 |
1
|
0 |
0 |
0 |
1
|
Institute of Human Genetics, University of Leipzig Medical Center
|
0 |
0 |
1
|
0 |
0 |
0 |
1
|
Broad Center for Mendelian Genomics, Broad Institute of MIT and Harvard
|
0 |
0 |
1
|
0 |
0 |
0 |
1
|
Zotz-Klimas Genetics Lab, MVZ Zotz Klimas
|
0 |
0 |
1
|
0 |
0 |
0 |
1
|
Neuberg Centre For Genomic Medicine, NCGM
|
1
|
0 |
0 |
0 |
0 |
0 |
1
|
Genomics England Pilot Project, Genomics England
|
0 |
1
|
0 |
0 |
0 |
0 |
1
|
Institute of Immunology and Genetics Kaiserslautern
|
1
|
0 |
0 |
0 |
0 |
0 |
1
|
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