Variants studied for Thrombophilia due to protein S deficiency, autosomal recessive

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

If a variant has more than one submission, it may be counted in more than one significance column. If this is the case, the total number of variants will be less than the sum of the other cells.

pathogenic	likely pathogenic	uncertain significance	likely benign	benign	total
58	14	130	141	24	366

Gene and significance breakdown #

Total genes and gene combinations: 4

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Gene or gene combination	pathogenic	likely pathogenic	uncertain significance	likely benign	benign	total
PROS1	56	14	129	141	24	363
ARL13B, DHFR2, NSUN3, PROS1, STX19	1	0	0	0	0	1
ARL13B, LOC123002313, LOC129937098, LOC129937099, PROS1, STX19	1	0	0	0	0	1
ARL13B, PROS1, STX19	0	0	1	0	0	1

Submitter and significance breakdown #

Total submitters: 4

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Submitter	pathogenic	likely pathogenic	uncertain significance	likely benign	benign	total
Labcorp Genetics (formerly Invitae), Labcorp	55	14	129	141	24	363
OMIM	3	0	0	0	0	3
Genome-Nilou Lab	0	0	0	0	1	1
Neuberg Centre For Genomic Medicine, NCGM	0	0	1	0	0	1

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