If a variant has more than one submission, it may be counted in more than one significance column. If this is the
case, the total number of variants will be less than the sum of the other cells.
pathogenic |
likely pathogenic |
uncertain significance |
likely benign |
benign |
not provided |
total |
17
|
12
|
569
|
131
|
1492
|
7
|
2209
|
Gene and significance breakdown #
Total genes and gene combinations: 21
Gene or gene combination |
pathogenic |
likely pathogenic |
uncertain significance |
likely benign |
benign |
not provided |
total |
TTN
|
17
|
10
|
507
|
117
|
1305
|
7
|
1947
|
LOC101927055, TTN
|
0 |
1
|
4
|
2
|
20
|
0 |
27
|
LOC126806425, TTN
|
0 |
1
|
5
|
2
|
19
|
0 |
27
|
LOC126806430, TTN
|
0 |
0 |
6
|
3
|
17
|
0 |
26
|
LOC126806422, TTN
|
0 |
0 |
4
|
1
|
15
|
0 |
19
|
LOC126806424, TTN
|
0 |
0 |
4
|
0 |
13
|
0 |
17
|
LOC126806420, TTN
|
0 |
0 |
4
|
0 |
12
|
0 |
16
|
LOC126806421, TTN
|
0 |
0 |
4
|
0 |
12
|
0 |
16
|
LOC126806423, TTN
|
0 |
0 |
3
|
1
|
12
|
0 |
16
|
LOC126806427, TTN
|
0 |
0 |
2
|
0 |
13
|
0 |
15
|
LOC126806431, TTN
|
0 |
0 |
6
|
0 |
9
|
0 |
15
|
LOC126806426, TTN
|
0 |
0 |
6
|
0 |
7
|
0 |
12
|
LOC126806429, TTN
|
0 |
0 |
1
|
1
|
10
|
0 |
12
|
LOC129935183, TTN
|
0 |
0 |
3
|
2
|
7
|
0 |
12
|
LOC126806428, TTN
|
0 |
0 |
1
|
0 |
10
|
0 |
11
|
LOC126806433, TTN
|
0 |
0 |
6
|
0 |
4
|
0 |
10
|
LOC129935184, TTN
|
0 |
0 |
1
|
1
|
4
|
0 |
5
|
LOC126806432, TTN
|
0 |
0 |
1
|
1
|
0 |
0 |
2
|
LOC129935182, TTN
|
0 |
0 |
1
|
0 |
1
|
0 |
2
|
LOC129935185, TTN
|
0 |
0 |
0 |
0 |
1
|
0 |
1
|
LOC129935186, TTN
|
0 |
0 |
0 |
0 |
1
|
0 |
1
|
Submitter and significance breakdown #
Submitter |
pathogenic |
likely pathogenic |
uncertain significance |
likely benign |
benign |
not provided |
total |
Illumina Laboratory Services, Illumina
|
0 |
0 |
510
|
125
|
1179
|
0 |
1814
|
Genome-Nilou Lab
|
0 |
0 |
0 |
0 |
635
|
0 |
635
|
Baylor Genetics
|
2
|
6
|
27
|
0 |
0 |
0 |
35
|
Centre for Mendelian Genomics, University Medical Centre Ljubljana
|
3
|
3
|
16
|
6
|
1
|
0 |
29
|
Phosphorus, Inc.
|
0 |
0 |
10
|
1
|
2
|
0 |
13
|
GeneReviews
|
4
|
0 |
0 |
0 |
0 |
4
|
8
|
Genetic Services Laboratory, University of Chicago
|
3
|
1
|
0 |
0 |
0 |
0 |
4
|
OMIM
|
3
|
0 |
0 |
0 |
0 |
0 |
3
|
GenomeConnect, ClinGen
|
0 |
0 |
0 |
0 |
0 |
3
|
3
|
Mendelics
|
2
|
0 |
0 |
0 |
0 |
0 |
2
|
Biochemical Molecular Genetic Laboratory, King Abdulaziz Medical City
|
0 |
1
|
1
|
0 |
0 |
0 |
2
|
Centogene AG - the Rare Disease Company
|
0 |
0 |
1
|
0 |
0 |
0 |
1
|
Juha Muilu Group; Institute for Molecular Medicine Finland (FIMM)
|
0 |
1
|
0 |
0 |
0 |
0 |
1
|
Institute of Human Genetics Munich, Klinikum Rechts Der Isar, TU München
|
1
|
0 |
0 |
0 |
0 |
0 |
1
|
Institute for Human Genetics and Genomic Medicine, Uniklinik RWTH Aachen
|
0 |
0 |
1
|
0 |
0 |
0 |
1
|
Foundation for Research in Genetics and Endocrinology, FRIGE's Institute of Human Genetics
|
0 |
0 |
1
|
0 |
0 |
0 |
1
|
Zotz-Klimas Genetics Lab, MVZ Zotz Klimas
|
0 |
0 |
1
|
0 |
0 |
0 |
1
|
Neuberg Centre For Genomic Medicine, NCGM
|
0 |
0 |
1
|
0 |
0 |
0 |
1
|
Clinical Genetics Laboratory, University Hospital Schleswig-Holstein
|
0 |
0 |
1
|
0 |
0 |
0 |
1
|
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