Variants studied for Ventricular tachycardia

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

If a variant has more than one submission, it may be counted in more than one significance column. If this is the case, the total number of variants will be less than the sum of the other cells.

pathogenic	likely pathogenic	uncertain significance	likely benign	benign	not provided	total
1	6	26	15	0	4	52

Gene and significance breakdown #

Total genes and gene combinations: 25

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Gene or gene combination	pathogenic	likely pathogenic	uncertain significance	likely benign	not provided	total
TTN	0	1	5	5	0	11
DSP	0	0	4	0	0	4
PKP2	1	1	1	1	0	4
SCN5A	0	1	1	1	1	4
CACNA1C	0	0	3	0	0	3
KCNJ2	0	0	0	0	3	3
AKAP9	0	0	1	1	0	2
ANK2	0	0	1	1	0	2
HCN4	0	0	2	0	0	2
KCNH2	0	0	2	0	0	2
CACNB2	0	0	0	1	0	1
HCN4, LOC105370890	0	0	1	0	0	1
LDB3	0	0	0	1	0	1
LMNA	0	1	0	0	0	1
LOC126806424, TTN	0	0	0	1	0	1
LOC126861898, MYH7	0	1	0	0	0	1
MYLK2	0	0	1	0	0	1
PTPN11	0	1	0	0	0	1
RAF1	0	0	1	0	0	1
RYR2	0	0	1	0	0	1
SNTA1	0	0	0	1	0	1
SOS1	0	0	1	0	0	1
TCAP	0	0	1	0	0	1
TRPM4	0	0	0	1	0	1
VCL	0	0	0	1	0	1

Submitter and significance breakdown #

Total submitters: 7

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Submitter	pathogenic	likely pathogenic	uncertain significance	likely benign	not provided	total
Center for Advanced Laboratory Medicine, UC San Diego Health, University of California San Diego	1	2	15	15	0	33
Blueprint Genetics	0	0	10	0	0	10
Cardiovascular Biomedical Research Unit, Royal Brompton & Harefield NHS Foundation Trust	0	0	0	0	4	4
Clinical Genetics Laboratory, Skane University Hospital Lund	0	2	0	0	0	2
Biesecker Lab/Clinical Genomics Section, National Institutes of Health	0	0	1	0	0	1
Agnes Ginges Centre for Molecular Cardiology, Centenary Institute	0	1	0	0	0	1
Centre for Mendelian Genomics, University Medical Centre Ljubljana	0	1	0	0	0	1

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