ClinVar Miner

Variants in gene combination A2M, KLRG1

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Minimum submission review status: Collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than one submission, it may be counted in more than one significance column. If this is the case, the total number of variants will be less than the sum of the other cells.

pathogenic likely pathogenic uncertain significance likely benign benign total
0 0 101 20 18 139

Condition and significance breakdown #

Total conditions: 5
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Condition uncertain significance likely benign benign total
not specified 98 4 1 103
A2M-related disorder 1 12 5 18
not provided 1 5 10 16
ALPHA-2-MACROGLOBULIN POLYMORPHISM 0 0 5 5
Megacolon 1 0 0 1

Submitter and significance breakdown #

Total submitters: 12
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Submitter uncertain significance likely benign benign total
Ambry Genetics 97 4 0 101
PreventionGenetics, part of Exact Sciences 0 12 5 17
Labcorp Genetics (formerly Invitae), Labcorp 0 5 8 13
Breakthrough Genomics, Breakthrough Genomics 0 0 6 6
OMIM 0 0 5 5
GeneDx 0 0 2 2
CeGaT Center for Human Genetics Tuebingen 0 1 1 2
Department of Pathology and Laboratory Medicine, Sinai Health System 2 0 0 2
Laboratory for Molecular Medicine, Mass General Brigham Personalized Medicine 0 0 1 1
ARUP Laboratories, Molecular Genetics and Genomics, ARUP Laboratories 0 0 1 1
Women's Health and Genetics/Laboratory Corporation of America, LabCorp 1 0 0 1
Clinical Genetics, Erasmus University Medical Center 1 0 0 1

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