ClinVar Miner

Variants in gene ABCB1

See also:
Minimum submission review status: Collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than one submission, it may be counted in more than one significance column. If this is the case, the total number of variants will be less than the sum of the other cells.

pathogenic likely pathogenic uncertain significance likely benign benign drug response risk factor not provided total
1 1 37 30 17 567 1 2 634

Condition and significance breakdown #

Total conditions: 11
Download table as spreadsheet
Condition pathogenic likely pathogenic uncertain significance likely benign benign drug response risk factor not provided total
Tramadol response 0 0 0 0 0 567 0 0 567
not specified 0 0 30 1 5 0 0 0 36
not provided 0 0 2 14 13 0 0 0 26
ABCB1-related condition 0 0 1 19 1 0 0 0 21
Inflammatory bowel disease 13 0 0 3 0 0 0 1 0 4
Colchicine resistance 1 0 0 0 0 0 0 0 1
Hereditary breast ovarian cancer syndrome 0 0 1 0 0 0 0 0 1
Idiopathic generalized epilepsy 0 1 0 0 0 0 0 0 1
MDR1 POLYMORPHISM 0 0 0 0 1 0 0 0 1
Neoplasm of ovary 0 0 0 0 0 0 0 1 1
Non-small cell lung carcinoma 0 0 0 0 0 0 0 1 1

Submitter and significance breakdown #

Total submitters: 15
Download table as spreadsheet
Submitter pathogenic likely pathogenic uncertain significance likely benign benign drug response risk factor not provided total
Bruce Budowle Laboratory, University of North Texas Health Science Center 0 0 0 0 0 567 0 0 567
Ambry Genetics 0 0 30 1 0 0 0 0 31
PreventionGenetics, part of Exact Sciences 0 0 1 19 1 0 0 0 21
Invitae 0 0 0 11 9 0 0 0 20
GeneDx 0 0 0 0 5 0 0 0 5
Eurofins Ntd Llc (ga) 0 0 0 0 4 0 0 0 4
CeGaT Center for Human Genetics Tuebingen 0 0 1 3 0 0 0 0 4
OMIM 1 0 0 0 1 0 1 0 3
Baylor Genetics 0 0 2 0 0 0 0 0 2
Database of Curated Mutations (DoCM) 0 0 0 0 0 0 0 2 2
Genomic Diagnostic Laboratory, Division of Genomic Diagnostics, Children's Hospital of Philadelphia 0 0 0 0 1 0 0 0 1
Department of Pathology and Laboratory Medicine, Sinai Health System 0 0 1 0 0 0 0 0 1
Johns Hopkins Genomics, Johns Hopkins University 0 0 1 0 0 0 0 0 1
Cell and Molecular Biology Laboratory, University of the Punjab Lahore 0 1 0 0 0 0 0 0 1
Molecular Oncology Research Center, Barretos Cancer Hospital 0 0 1 0 0 0 0 0 1

The information on this website is not intended for direct diagnostic use or medical decision-making without review by a genetics professional. Individuals should not change their health behavior solely on the basis of information contained on this website. Neither the University of Utah nor the National Institutes of Health independently verfies the submitted information. If you have questions about the information contained on this website, please see a health care professional.