ClinVar Miner

Variants in gene AIP

See also:
Minimum submission review status: Collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than one submission, it may be counted in more than one significance column. If this is the case, the total number of variants will be less than the sum of the other cells.

pathogenic likely pathogenic uncertain significance likely benign benign drug response not provided total
36 14 434 309 31 1 50 784

Condition and significance breakdown #

Total conditions: 13
Download table as spreadsheet
Condition pathogenic likely pathogenic uncertain significance likely benign benign drug response not provided total
not provided 25 4 328 227 16 0 0 581
Hereditary cancer-predisposing syndrome 8 2 241 178 10 0 0 435
Somatotroph adenoma 9 8 40 10 15 0 48 114
Familial isolated pituitary adenoma 0 1 7 1 0 0 0 9
not specified 0 0 2 1 3 0 0 6
AIP-related condition 0 0 3 0 0 0 0 3
Pituitary adenoma predisposition 2 0 1 0 0 0 0 3
Pituitary dependent hypercortisolism; Somatotroph adenoma 0 0 2 1 0 0 0 3
Acroleukopathy, symmetric; Pituitary dependent hypercortisolism; Somatotroph adenoma 0 0 2 0 0 0 0 2
Inborn genetic diseases 0 0 2 0 0 0 0 2
AIP-Related Familial Isolated Pituitary Adenomas 0 0 0 0 0 0 1 1
Dopamine agonists response 0 0 0 0 0 1 0 1
Pituitary dependent hypercortisolism 0 0 0 0 0 0 1 1

Submitter and significance breakdown #

Total submitters: 31
Download table as spreadsheet
Submitter pathogenic likely pathogenic uncertain significance likely benign benign drug response not provided total
Invitae 25 2 309 222 11 0 0 569
Ambry Genetics 8 2 237 176 9 0 0 432
GeneDx 1 0 38 9 8 0 0 56
GeneReviews 0 5 0 1 0 0 49 55
Baylor Genetics 1 3 30 0 0 0 0 34
Illumina Laboratory Services, Illumina 0 0 7 9 15 0 0 31
Sema4, Sema4 0 0 12 13 2 0 0 27
CeGaT Center for Human Genetics Tuebingen 2 2 2 3 1 0 0 10
OMIM 9 0 0 0 0 0 0 9
St. Jude Molecular Pathology, St. Jude Children's Research Hospital 0 0 8 1 0 0 0 9
Institute for Clinical Genetics, University Hospital TU Dresden, University Hospital TU Dresden 0 0 8 0 0 0 0 8
Preventiongenetics, part of Exact Sciences 0 0 3 0 2 0 0 5
Fulgent Genetics, Fulgent Genetics 0 0 4 1 0 0 0 5
Eurofins Ntd Llc (ga) 0 0 3 0 0 0 0 3
Department of Pathology and Laboratory Medicine, Sinai Health System 0 0 1 2 0 0 0 3
Diagnostic Laboratory, Department of Genetics, University Medical Center Groningen 0 0 1 0 2 0 0 3
Genetic Services Laboratory, University of Chicago 0 0 1 1 0 0 0 2
Laboratory for Molecular Medicine, Mass General Brigham Personalized Medicine 0 0 1 0 1 0 0 2
Genome Diagnostics Laboratory, University Medical Center Utrecht 0 0 0 0 2 0 0 2
Korbonits Lab, Queen Mary University of London 0 1 1 0 0 0 0 2
Clinical Genetics DNA and cytogenetics Diagnostics Lab, Erasmus MC, Erasmus Medical Center 0 0 1 1 0 0 0 2
KCCC/NGS Laboratory, Kuwait Cancer Control Center 0 0 0 0 2 0 0 2
Revvity Omics, Revvity Omics 0 0 1 0 0 0 0 1
Mendelics 0 0 1 0 0 0 0 1
Aziz Sancar Institute of Experimental Medicine, Istanbul University 1 0 0 0 0 1 0 1
Center for Genomic Medicine, Rigshospitalet, Copenhagen University Hospital 0 0 0 0 1 0 0 1
Joint Genome Diagnostic Labs from Nijmegen and Maastricht, Radboudumc and MUMC+ 0 0 1 0 0 0 0 1
Institute of Human Genetics, University of Leipzig Medical Center 0 0 1 0 0 0 0 1
Genome Diagnostics Laboratory, Amsterdam University Medical Center 0 0 0 1 0 0 0 1
GenomeConnect - Invitae Patient Insights Network 0 0 0 0 0 0 1 1
Molecular Genetics, Labor Dr. Heidrich & Kollegen MVZ GmbH 0 0 1 0 0 0 0 1

The information on this website is not intended for direct diagnostic use or medical decision-making without review by a genetics professional. Individuals should not change their health behavior solely on the basis of information contained on this website. Neither the University of Utah nor the National Institutes of Health independently verfies the submitted information. If you have questions about the information contained on this website, please see a health care professional.