Variants in gene ARHGEF28

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

If a variant has more than one submission, it may be counted in more than one significance column. If this is the case, the total number of variants will be less than the sum of the other cells.

pathogenic	likely pathogenic	uncertain significance	likely benign	benign	total
0	0	186	102	116	383

Condition and significance breakdown #

Total conditions: 4

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Condition	uncertain significance	likely benign	benign	total
not specified	142	12	26	180
not provided	9	28	111	138
ARHGEF28-related disorder	47	71	4	122
Meniere disease	5	0	0	5

Submitter and significance breakdown #

Total submitters: 14

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Submitter	uncertain significance	likely benign	benign	total
Ambry Genetics	141	10	0	151
PreventionGenetics, part of Exact Sciences	47	73	26	146
GeneDx	0	0	96	96
Breakthrough Genomics, Breakthrough Genomics	1	4	66	71
Genome Diagnostics Laboratory, Amsterdam University Medical Center	0	6	19	25
Clinical Genetics DNA and cytogenetics Diagnostics Lab, Erasmus MC, Erasmus Medical Center	0	5	20	25
Clinical Genetics, Academic Medical Center	0	1	22	23
CeGaT Center for Human Genetics Tuebingen	5	15	2	22
Labcorp Genetics (formerly Invitae), Labcorp	0	6	13	19
Center for Computational Biology & Bioinformatics, University of California, San Diego	5	0	0	5
Quest Diagnostics Nichols Institute San Juan Capistrano	3	0	0	3
ARUP Laboratories, Cytogenetics and Genomic Microarray, ARUP Laboratories	1	0	0	1
Human Genome and Stem Cell Research Center, Department of Genetics and Evolutionary Biology, Institute of Biosciences, University of São Paulo	1	0	0	1
Joint Genome Diagnostic Labs from Nijmegen and Maastricht, Radboudumc and MUMC+	0	0	1	1

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