ClinVar Miner

Variants in gene BARD1

Minimum submission review status: Collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than one submission, it may be counted in more than one significance column. If this is the case, the total number of variants will be less than the sum of the other cells.

pathogenic likely pathogenic uncertain significance likely benign benign risk factor not provided total
231 106 1526 639 71 1 2 2378

Condition and significance breakdown #

Total conditions: 18
Download table as spreadsheet
Condition pathogenic likely pathogenic uncertain significance likely benign benign risk factor not provided total
Familial cancer of breast 159 63 1117 281 45 0 0 1621
Hereditary cancer-predisposing syndrome 120 30 936 468 28 0 0 1542
not provided 27 24 251 130 17 0 2 434
not specified 0 0 77 138 42 0 0 241
Malignant tumor of breast 5 2 34 18 5 0 0 64
Hereditary breast and ovarian cancer syndrome 5 5 7 1 0 0 0 18
Breast neoplasm 1 0 5 2 0 0 0 7
Triple-Negative Breast Cancer Finding 2 0 2 1 0 0 0 5
Breast and/or ovarian cancer 3 1 0 0 0 0 0 4
Familial ovarian cancer 0 0 3 1 0 0 0 4
Carcinoma of colon 0 0 2 1 0 0 0 3
Familial pancreatic carcinoma 0 0 3 0 0 0 0 3
Breast cancer, susceptibility to 1 0 0 0 0 1 0 2
Hereditary cancer 0 0 2 0 0 0 0 2
Lung cancer 0 0 0 1 0 0 0 1
Multiple myeloma 0 1 0 0 0 0 0 1
Neoplasm of ovary 0 1 0 0 0 0 0 1
Thyroid cancer 0 0 1 0 0 0 0 1

Submitter and significance breakdown #

Total submitters: 40
Download table as spreadsheet
Submitter pathogenic likely pathogenic uncertain significance likely benign benign risk factor not provided total
Invitae 152 55 1075 295 29 0 0 1606
Ambry Genetics 94 23 700 292 16 0 0 1125
Color Health, Inc 54 11 553 290 25 0 0 933
GeneDx 25 17 192 125 29 0 0 388
Integrated Genetics/Laboratory Corporation of America 5 7 79 40 11 0 0 142
Quest Diagnostics Nichols Institute San Juan Capistrano 3 4 79 28 20 0 0 130
Mendelics 3 2 56 15 8 0 0 84
Department of Pathology and Laboratory Medicine,Sinai Health System 5 0 50 22 5 0 0 82
Illumina Clinical Services Laboratory,Illumina 0 0 39 11 13 0 0 62
Counsyl 2 3 35 14 6 0 0 60
PreventionGenetics, PreventionGenetics 0 0 14 8 18 0 0 40
University of Washington Department of Laboratory Medicine, University of Washington 0 1 0 32 0 0 0 33
Fulgent Genetics,Fulgent Genetics 3 0 20 0 0 0 0 23
CeGaT Praxis fuer Humangenetik Tuebingen 4 3 15 1 0 0 0 23
ARUP Laboratories, Molecular Genetics and Genomics,ARUP Laboratories 0 0 1 4 13 0 0 18
GeneKor MSA 1 1 13 0 0 0 0 15
Cancer Genomics Group,Japanese Foundation For Cancer Research 2 2 7 1 0 0 0 12
Institute of Human Genetics, University of Leipzig Medical Center 1 0 3 1 2 0 0 7
King Laboratory,University of Washington 5 0 0 0 0 0 0 5
Lab. Molecular Oncology,VUB, Free University of Brussels 2 0 2 1 0 0 0 5
Cancer Genetics Service,National Cancer Centre Singapore 1 1 3 0 0 0 0 5
Centre for Mendelian Genomics,University Medical Centre Ljubljana 0 0 3 0 1 0 0 4
CZECANCA consortium 3 1 0 0 0 0 0 4
Baylor Genetics 0 0 3 0 0 0 0 3
Laboratory for Molecular Medicine,Partners HealthCare Personalized Medicine 0 0 0 0 3 0 0 3
HudsonAlpha Institute for Biotechnology, HudsonAlpha Institute for Biotechnology 2 1 0 0 0 0 0 3
Institute for Biomarker Research,Medical Diagnostic Laboratories, L.L.C. 0 0 2 1 0 0 0 3
Institute of Medical Genetics and Applied Genomics, University Hospital Tübingen 3 0 0 0 0 0 0 3
GenomeConnect, ClinGen 0 0 0 0 0 0 2 2
OMIM 0 0 0 0 0 1 0 1
Cincinnati Children's Hospital Medical Center Laboratory of Genetics and Genomics,Cincinnati Children's Hospital Medical Center 0 0 0 0 1 0 0 1
Genetic Services Laboratory, University of Chicago 1 0 0 0 0 0 0 1
Clinical Genetics laboratory, University of Goettingen 0 0 1 0 0 0 0 1
EGL Genetic Diagnostics, Eurofins Clinical Diagnostics 0 0 0 1 0 0 0 1
Genomic Research Center, Shahid Beheshti University of Medical Sciences 0 0 0 1 0 0 0 1
Vantari Genetics 0 0 0 0 1 0 0 1
Center of Medical Genetics and Primary Health Care 0 0 0 0 1 0 0 1
Yang An-Suei Laboratory,Academia Sinica 1 0 0 0 0 0 0 1
German Consortium for Hereditary Breast and Ovarian Cancer Center Cologne,University Hospital Cologne 0 1 0 0 0 0 0 1
Xiao lab, Department of Pathology, Memorial Sloan Kettering Cancer Center 0 1 0 0 0 0 0 1

The information on this website is not intended for direct diagnostic use or medical decision-making without review by a genetics professional. Individuals should not change their health behavior solely on the basis of information contained on this website. Neither the University of Utah nor the National Institutes of Health independently verfies the submitted information. If you have questions about the information contained on this website, please see a health care professional.