ClinVar Miner

Variants in gene combination FAN1, MTMR10

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Minimum submission review status: Collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than one submission, it may be counted in more than one significance column. If this is the case, the total number of variants will be less than the sum of the other cells.

pathogenic likely pathogenic uncertain significance likely benign benign total
12 19 124 58 43 240

Condition and significance breakdown #

Total conditions: 6
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Condition pathogenic likely pathogenic uncertain significance likely benign benign total
not provided 5 2 22 49 43 114
Karyomegalic interstitial nephritis 10 16 50 8 2 82
Inborn genetic diseases 0 0 33 3 0 36
not specified 0 0 28 1 3 32
FAN1-related disorder 1 1 7 9 3 21
Hereditary breast ovarian cancer syndrome 0 0 1 0 0 1

Submitter and significance breakdown #

Total submitters: 27
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Submitter pathogenic likely pathogenic uncertain significance likely benign benign total
Fulgent Genetics, Fulgent Genetics 5 11 47 8 0 71
Labcorp Genetics (formerly Invitae), Labcorp 5 1 16 32 14 68
Ambry Genetics 0 0 60 4 0 64
GeneDx 0 0 5 15 32 52
PreventionGenetics, part of Exact Sciences 1 1 7 9 4 22
Breakthrough Genomics, Breakthrough Genomics 0 0 0 7 13 20
CeGaT Center for Human Genetics Tuebingen 1 0 0 5 1 7
OMIM 6 0 0 0 0 6
Revvity Omics, Revvity 1 0 2 0 0 3
Genome Diagnostics Laboratory, University Medical Center Utrecht 0 0 0 2 1 3
Victorian Clinical Genetics Services, Murdoch Childrens Research Institute 2 1 0 0 0 3
Genome Diagnostics Laboratory, Amsterdam University Medical Center 0 0 0 1 2 3
Yale Center for Mendelian Genomics, Yale University 0 2 0 0 0 2
Clinical Genetics DNA and cytogenetics Diagnostics Lab, Erasmus MC, Erasmus Medical Center 0 0 0 2 0 2
Genome-Nilou Lab 0 0 0 0 2 2
Laboratorio de Genetica e Diagnostico Molecular, Hospital Israelita Albert Einstein 0 2 0 0 0 2
Baylor Genetics 0 0 1 0 0 1
Women's Health and Genetics/Laboratory Corporation of America, LabCorp 0 0 1 0 0 1
Center of Genomic medicine, Geneva, University Hospital of Geneva 1 0 0 0 0 1
Center for Genomic Medicine, Rigshospitalet, Copenhagen University Hospital 0 1 0 0 0 1
Joint Genome Diagnostic Labs from Nijmegen and Maastricht, Radboudumc and MUMC+ 0 0 0 0 1 1
Department of Pathology and Laboratory Medicine, Sinai Health System 0 1 0 0 0 1
Laboratory of Diagnostic Genome Analysis, Leiden University Medical Center (LUMC) 0 0 0 1 0 1
Gharavi Laboratory, Columbia University 0 0 1 0 0 1
Molecular Oncology Research Center, Barretos Cancer Hospital 0 0 1 0 0 1
3billion 1 0 0 0 0 1
Molecular Genetics, Royal Melbourne Hospital 1 0 0 0 0 1

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