Variants in gene HLA-DRB1

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

If a variant has more than one submission, it may be counted in more than one significance column. If this is the case, the total number of variants will be less than the sum of the other cells.

pathogenic	likely pathogenic	uncertain significance	likely benign	benign	risk factor	total
1	1	6	19	5	2	34

Condition and significance breakdown #

Total conditions: 8

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Condition	pathogenic	likely pathogenic	uncertain significance	likely benign	benign	risk factor	total
not provided	0	0	4	14	4	0	22
HLA-DRB1-related disorder	0	0	0	5	0	0	5
Multiple sclerosis, susceptibility to	0	1	2	0	0	0	3
Multiple sclerosis, susceptibility to 1	0	0	0	0	0	1	1
Peritoneal Gliomatosis	0	0	1	0	0	0	1
Pulmonary artery atresia	1	0	0	0	0	0	1
Sarcoidosis, susceptibility to, 1	0	0	0	0	0	1	1
not specified	0	0	0	0	1	0	1

Submitter and significance breakdown #

Total submitters: 11

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Submitter	pathogenic	likely pathogenic	uncertain significance	likely benign	benign	risk factor	total
CeGaT Center for Human Genetics Tuebingen	0	0	1	14	2	0	17
PreventionGenetics, part of Exact Sciences	0	0	0	5	0	0	5
Genomic Medicine Center of Excellence, King Faisal Specialist Hospital and Research Centre	0	1	2	0	0	0	3
Breakthrough Genomics, Breakthrough Genomics	0	0	3	0	0	0	3
OMIM	0	0	0	0	0	2	2
GeneDx	0	0	0	0	2	0	2
Department of Pathology and Laboratory Medicine, Sinai Health System	0	0	2	0	0	0	2
Genome Diagnostics Laboratory, University Medical Center Utrecht	0	0	0	0	1	0	1
Clinical Genetics DNA and cytogenetics Diagnostics Lab, Erasmus MC, Erasmus Medical Center	0	0	0	0	1	0	1
Treehouse Childhood Cancer Initiative, UC Santa Cruz	0	0	1	0	0	0	1
Henan Key Laboratory of Chronic Disease Management, Central China Fuwai Hospital of Zhengzhou University, Fuwai Central China Cardiovascular Hospital & Central China Branch of National Center for Cardiovascular Diseases	1	0	0	0	0	0	1

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