Variants in gene IL2RB - ClinVar Miner

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

If a variant has more than one submission, it may be counted in more than one significance column. If this is the case, the total number of variants will be less than the sum of the other cells.

pathogenic	likely pathogenic	uncertain significance	likely benign	benign	total
9	6	192	210	27	434

Condition and significance breakdown #

Total conditions: 5

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Condition	pathogenic	likely pathogenic	uncertain significance	likely benign	benign	total
not provided	4	6	163	207	21	395
not specified	0	0	41	3	10	54
IL2RB-related disorder	0	0	4	4	11	19
Immunodeficiency 63 with lymphoproliferation and autoimmunity	4	0	4	0	4	12
Ichthyosis	1	0	0	0	0	1

Submitter and significance breakdown #

Total submitters: 17

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Submitter	pathogenic	likely pathogenic	uncertain significance	likely benign	benign	total
Labcorp Genetics (formerly Invitae), Labcorp	4	6	158	197	20	385
Ambry Genetics	0	0	41	3	0	44
Breakthrough Genomics, Breakthrough Genomics	0	0	2	6	12	20
PreventionGenetics, part of Exact Sciences	0	0	4	4	11	19
CeGaT Center for Human Genetics Tuebingen	0	1	1	14	1	17
Unidad de Genómica Garrahan, Hospital de Pediatría Garrahan	0	0	0	0	10	10
OMIM	4	0	0	0	0	4
Mayo Clinic Laboratories, Mayo Clinic	0	0	4	0	0	4
Genome-Nilou Lab	0	0	0	0	4	4
GeneDx	0	0	3	0	0	3
Genome Diagnostics Laboratory, University Medical Center Utrecht	0	0	0	3	0	3
Clinical Genetics DNA and cytogenetics Diagnostics Lab, Erasmus MC, Erasmus Medical Center	0	0	0	3	0	3
Baylor Genetics	0	0	1	0	0	1
Revvity Omics, Revvity	0	0	1	0	0	1
Laboratoire de Génétique Moléculaire, CHU Bordeaux	1	0	0	0	0	1
3billion	0	0	1	0	0	1
Neuberg Centre For Genomic Medicine, NCGM	0	0	1	0	0	1

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