ClinVar Miner

Variants in gene KCNE3

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Minimum submission review status: Collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than one submission, it may be counted in more than one significance column. If this is the case, the total number of variants will be less than the sum of the other cells.

pathogenic likely pathogenic uncertain significance likely benign benign total
1 0 80 37 14 119

Condition and significance breakdown #

Total conditions: 8
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Condition pathogenic uncertain significance likely benign benign total
Cardiovascular phenotype 0 44 22 3 69
Brugada syndrome 6 1 47 13 4 64
not provided 0 11 5 9 25
not specified 0 4 4 4 12
Brugada syndrome 0 8 4 0 11
KCNE3-related disorder 0 0 2 0 2
Long QT syndrome 0 2 0 0 2
Prolonged QT interval 0 2 0 0 2

Submitter and significance breakdown #

Total submitters: 20
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Submitter pathogenic uncertain significance likely benign benign total
Ambry Genetics 0 44 22 3 69
Labcorp Genetics (formerly Invitae), Labcorp 0 47 13 2 62
GeneDx 0 5 7 12 24
Fulgent Genetics, Fulgent Genetics 0 10 0 2 12
Illumina Laboratory Services, Illumina 0 7 3 0 10
Breakthrough Genomics, Breakthrough Genomics 0 4 2 4 10
PreventionGenetics, part of Exact Sciences 0 0 2 1 3
Women's Health and Genetics/Laboratory Corporation of America, LabCorp 0 0 1 2 3
Biesecker Lab/Clinical Genomics Section, National Institutes of Health 0 1 1 0 2
Laboratory for Molecular Medicine, Mass General Brigham Personalized Medicine 0 2 0 0 2
ARUP Laboratories, Molecular Genetics and Genomics, ARUP Laboratories 0 1 0 1 2
Center For Human Genetics And Laboratory Diagnostics, Dr. Klein, Dr. Rost And Colleagues 0 2 0 0 2
AiLife Diagnostics, AiLife Diagnostics 0 2 0 0 2
Dept of Medical Biology, Uskudar University 0 2 0 0 2
OMIM 1 0 0 0 1
Revvity Omics, Revvity 0 1 0 0 1
Mayo Clinic Laboratories, Mayo Clinic 0 1 0 0 1
Stanford Center for Inherited Cardiovascular Disease, Stanford University 0 1 0 0 1
CeGaT Center for Human Genetics Tuebingen 0 1 0 0 1
Lildballe Lab, Aarhus University Hospital 0 1 0 0 1

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