ClinVar Miner

Variants in gene KDM4B

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Minimum submission review status: Collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than one submission, it may be counted in more than one significance column. If this is the case, the total number of variants will be less than the sum of the other cells.

pathogenic likely pathogenic uncertain significance likely benign benign total
6 22 185 52 15 268

Condition and significance breakdown #

Total conditions: 11
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Condition pathogenic likely pathogenic uncertain significance likely benign benign total
not provided 2 5 78 43 15 138
Inborn genetic diseases 0 2 78 4 0 84
Intellectual developmental disorder, autosomal dominant 65 4 13 20 0 0 37
KDM4B-related disorder 0 0 9 5 0 14
not specified 0 0 6 1 0 7
Neurodevelopmental delay 0 2 0 0 0 2
See cases 0 0 2 0 0 2
Developmental disorder 0 0 1 0 0 1
Neurodevelopmental abnormality 0 0 1 0 0 1
Neurodevelopmental disorder 0 1 0 0 0 1
Syndromic global developmental delay 0 1 0 0 0 1

Submitter and significance breakdown #

Total submitters: 37
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Submitter pathogenic likely pathogenic uncertain significance likely benign benign total
Ambry Genetics 0 2 78 4 0 84
GeneDx 2 5 54 0 3 64
CeGaT Center for Human Genetics Tuebingen 0 0 10 41 0 51
Labcorp Genetics (formerly Invitae), Labcorp 0 0 8 6 12 26
PreventionGenetics, part of Exact Sciences 0 0 9 5 0 14
Breakthrough Genomics, Breakthrough Genomics 0 0 0 3 9 12
Greenwood Genetic Center Diagnostic Laboratories, Greenwood Genetic Center 0 1 5 0 0 6
Women's Health and Genetics/Laboratory Corporation of America, LabCorp 0 0 5 1 0 6
OMIM 4 0 0 0 0 4
ARUP Laboratories, Molecular Genetics and Genomics, ARUP Laboratories 0 1 3 0 0 4
Institute of Human Genetics, University of Leipzig Medical Center 0 4 0 0 0 4
Laboratorio de Genetica e Diagnostico Molecular, Hospital Israelita Albert Einstein 0 0 4 0 0 4
Revvity Omics, Revvity 0 0 3 0 0 3
Pittsburgh Clinical Genomics Laboratory, University of Pittsburgh Medical Center 0 0 3 0 0 3
Institute of Human Genetics, University of Goettingen 0 0 2 0 0 2
Neuberg Centre For Genomic Medicine, NCGM 0 0 2 0 0 2
Baylor Genetics 0 0 1 0 0 1
Amsterdam UMC Genome Diagnostics, Amsterdam University Medical Center 0 1 0 0 0 1
Fulgent Genetics, Fulgent Genetics 0 0 1 0 0 1
Genomic Medicine Center of Excellence, King Faisal Specialist Hospital and Research Centre 0 0 1 0 0 1
Illumina Laboratory Services, Illumina 0 0 1 0 0 1
Institute of Human Genetics, FAU Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg 0 1 0 0 0 1
Clinical Genomics Laboratory, Washington University in St. Louis 0 1 0 0 0 1
Laboratory of Molecular Genetics (Pr. Bezieau's lab), CHU de Nantes 0 1 0 0 0 1
Centre de Biologie Pathologie Génétique, Centre Hospitalier Universitaire de Lille 0 1 0 0 0 1
Institute of Human Genetics, University of Wuerzburg 0 0 1 0 0 1
Center For Human Genetics And Laboratory Diagnostics, Dr. Klein, Dr. Rost And Colleagues 0 1 0 0 0 1
Department of Pathology and Laboratory Medicine, Sinai Health System 0 1 0 0 0 1
Laboratory of Medical Genetics Unit, Bambino Gesù Children's Hospital 0 1 0 0 0 1
Institute of Medical Genetics and Applied Genomics, University Hospital Tübingen 0 1 0 0 0 1
University of Washington Department of Laboratory Medicine, University of Washington 0 1 0 0 0 1
Department of Genetics, Rouen University Hospital, Normandy Center for Genomic and Personalized Medicine 0 0 1 0 0 1
Zotz-Klimas Genetics Lab, MVZ Zotz Klimas 0 0 1 0 0 1
Institute of Human Genetics, University Hospital Muenster 0 0 1 0 0 1
New York Genome Center 0 1 0 0 0 1
Molecular Genetics Lab, CHRU Brest 0 0 1 0 0 1
Institute of Human Genetics, Clinical Exome/Genome Diagnostics Group, University Hospital Bonn 0 0 1 0 0 1

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