ClinVar Miner

Variants in gene LAMA4

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Minimum submission review status: Collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than one submission, it may be counted in more than one significance column. If this is the case, the total number of variants will be less than the sum of the other cells.

pathogenic likely pathogenic uncertain significance likely benign benign not provided total
2 1 214 163 73 3 390

Condition and significance breakdown #

Total conditions: 14
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Condition pathogenic likely pathogenic uncertain significance likely benign benign not provided total
not specified 0 0 57 106 63 3 205
Dilated cardiomyopathy 1JJ 2 0 82 55 46 0 173
not provided 0 1 82 6 4 0 91
Cardiovascular phenotype 0 0 27 25 6 0 58
Cardiomyopathy 0 0 21 13 11 0 45
Primary familial hypertrophic cardiomyopathy 0 0 6 0 0 0 6
Primary dilated cardiomyopathy 0 0 5 0 0 0 5
Arrhythmogenic right ventricular cardiomyopathy 0 0 2 0 0 0 2
Wolff-Parkinson-White pattern 0 0 2 0 0 0 2
Brugada syndrome 9 0 0 1 0 0 0 1
Catecholaminergic polymorphic ventricular tachycardia type 1 0 0 1 0 0 0 1
Familial atrial fibrillation 0 0 1 0 0 0 1
Left ventricular noncompaction cardiomyopathy 0 0 1 0 0 0 1
Spinocerebellar ataxia 19 0 0 1 0 0 0 1

Submitter and significance breakdown #

Total submitters: 21
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Submitter pathogenic likely pathogenic uncertain significance likely benign benign not provided total
GeneDx 0 1 57 69 59 0 186
Invitae 0 0 74 37 37 0 148
Laboratory for Molecular Medicine,Partners HealthCare Personalized Medicine 0 0 50 53 36 3 142
Ambry Genetics 0 0 27 25 6 0 58
CHEO Genetics Diagnostic Laboratory,Children's Hospital of Eastern Ontario 0 0 21 13 11 0 45
Biesecker Lab/Human Development Section,National Institutes of Health 0 0 21 6 10 0 37
Diagnostic Laboratory, Department of Genetics,University Medical Center Groningen 0 0 4 23 9 0 36
DNA and Cytogenetics Diagnostics Unit,Erasmus Medical Center 0 0 1 6 11 0 18
PreventionGenetics 0 0 0 0 14 0 14
Blueprint Genetics, 0 0 12 0 0 0 12
Stanford Center for Inherited Cardiovascular Disease,Stanford University 0 0 10 0 0 0 10
Genome Diagnostics Laboratory,University Medical Center Utrecht 0 0 2 1 6 0 9
ARUP Laboratories, Molecular Genetics and Genomics,ARUP Laboratories 0 0 4 0 2 0 6
EGL Genetic Diagnostics,Eurofins Clinical Diagnostics 0 0 4 1 1 0 6
Fulgent Genetics 0 0 4 0 0 0 4
Clinical Molecular Genetics Laboratory,Johns Hopkins All Children's Hospital 0 0 3 0 0 0 3
OMIM 2 0 0 0 0 0 2
Lupski Lab, Baylor-Hopkins CMG,Baylor College of Medicine 0 0 2 0 0 0 2
Laboratory of Genetics and Genomics,Cincinnati Children's Hospital Medical Center 0 0 0 0 2 0 2
Molecular Diagnostic Laboratory for Inherited Cardiovascular Disease,Montreal Heart Institute 0 0 1 0 0 0 1
Phosphorus, Inc. 0 0 1 0 0 0 1

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