ClinVar Miner

Variants in gene MPO

See also:
Minimum submission review status: Collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than one submission, it may be counted in more than one significance column. If this is the case, the total number of variants will be less than the sum of the other cells.

pathogenic likely pathogenic uncertain significance likely benign benign total
3 6 43 10 4 58

Condition and significance breakdown #

Total conditions: 7
Download table as spreadsheet
Condition pathogenic likely pathogenic uncertain significance likely benign benign total
not specified 0 0 35 2 1 38
not provided 1 3 3 3 4 12
MPO-related disorder 0 2 0 3 2 7
Myeloperoxidase deficiency 3 2 1 1 0 5
Myeloperoxidase deficiency; Alzheimer disease type 1 0 1 3 1 0 5
Alzheimer disease 0 0 1 0 0 1
Alzheimer disease type 1 0 0 1 0 0 1

Submitter and significance breakdown #

Total submitters: 20
Download table as spreadsheet
Submitter pathogenic likely pathogenic uncertain significance likely benign benign total
Ambry Genetics 0 0 34 1 0 35
PreventionGenetics, part of Exact Sciences 0 2 0 3 2 7
Department of Pathology and Laboratory Medicine, Sinai Health System 0 2 4 0 0 6
CeGaT Center for Human Genetics Tuebingen 0 0 2 2 1 5
Breakthrough Genomics, Breakthrough Genomics 0 0 1 0 3 4
GeneDx 0 3 0 0 0 3
Labcorp Genetics (formerly Invitae), Labcorp 0 0 0 1 2 3
OMIM 2 0 0 0 0 2
Women's Health and Genetics/Laboratory Corporation of America, LabCorp 0 0 1 1 0 2
Fulgent Genetics, Fulgent Genetics 0 1 0 1 0 2
Laboratory for Molecular Medicine, Mass General Brigham Personalized Medicine 0 0 0 0 1 1
Revvity Omics, Revvity 1 0 0 0 0 1
Genome Diagnostics Laboratory, University Medical Center Utrecht 1 0 0 0 0 1
Mendelics 0 0 1 0 0 1
Joint Genome Diagnostic Labs from Nijmegen and Maastricht, Radboudumc and MUMC+ 1 0 0 0 0 1
Centre for Mendelian Genomics, University Medical Centre Ljubljana 0 0 1 0 0 1
Institute of Medical Genetics and Applied Genomics, University Hospital Tübingen 0 1 0 0 0 1
Broad Center for Mendelian Genomics, Broad Institute of MIT and Harvard 0 0 0 1 0 1
Reproductive Health Research and Development, BGI Genomics 0 0 1 0 0 1
Neuberg Centre For Genomic Medicine, NCGM 0 0 1 0 0 1

The information on this website is not intended for direct diagnostic use or medical decision-making without review by a genetics professional. Individuals should not change their health behavior solely on the basis of information contained on this website. Neither the University of Utah nor the National Institutes of Health independently verfies the submitted information. If you have questions about the information contained on this website, please see a health care professional.