Variants in gene TLR2 - ClinVar Miner

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

If a variant has more than one submission, it may be counted in more than one significance column. If this is the case, the total number of variants will be less than the sum of the other cells.

pathogenic	likely pathogenic	uncertain significance	likely benign	benign	risk factor	not provided	total
0	0	64	16	13	3	3	92

Condition and significance breakdown #

Total conditions: 11

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Condition	uncertain significance	likely benign	benign	risk factor	not provided	total
not specified	54	2	0	0	0	56
not provided	3	9	5	0	2	17
TLR2-related disorder	0	4	11	0	0	15
Leprosy, susceptibility to, 3; Mycobacterium tuberculosis, susceptibility to; Colorectal cancer	2	1	0	0	0	3
COVID-19–associated multisystem inflammatory syndrome in adults	2	0	0	0	0	2
Leprosy, susceptibility to, 3; Colorectal cancer	2	0	0	0	0	2
Colorectal cancer	1	0	0	0	0	1
Colorectal cancer, susceptibility to	0	0	0	1	0	1
Hereditary angioedema with normal C1Inh	0	0	0	0	1	1
Leprosy, susceptibility to, 3	0	0	0	1	0	1
Mycobacterium tuberculosis, susceptibility to	0	0	0	1	0	1

Submitter and significance breakdown #

Total submitters: 13

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Submitter	uncertain significance	likely benign	benign	risk factor	not provided	total
Ambry Genetics	54	2	0	0	0	56
PreventionGenetics, part of Exact Sciences	0	4	11	0	0	15
Labcorp Genetics (formerly Invitae), Labcorp	0	6	5	0	0	11
Department of Pathology and Laboratory Medicine, Sinai Health System	5	0	0	0	0	5
Breakthrough Genomics, Breakthrough Genomics	0	1	4	0	0	5
OMIM	0	0	0	3	0	3
CeGaT Center for Human Genetics Tuebingen	0	3	0	0	0	3
Human Evolutionary Genetics, Institut Pasteur	0	0	0	0	2	2
Center for Genomics, Ann and Robert H. Lurie Children's Hospital of Chicago	2	0	0	0	0	2
HLA Laboratory, Instituto Nacional de Enfermedades Respiratorias Ismael Cosio Villegas	2	0	0	0	0	2
Fulgent Genetics, Fulgent Genetics	0	1	0	0	0	1
CeMIA	0	0	0	0	1	1
Laboratorio de Genetica e Diagnostico Molecular, Hospital Israelita Albert Einstein	1	0	0	0	0	1

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