Variants in gene TNFSF11

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

If a variant has more than one submission, it may be counted in more than one significance column. If this is the case, the total number of variants will be less than the sum of the other cells.

pathogenic	likely pathogenic	uncertain significance	likely benign	benign	total
3	1	52	43	10	105

Condition and significance breakdown #

Total conditions: 8

Download table as spreadsheet

Condition	pathogenic	likely pathogenic	uncertain significance	likely benign	benign	total
not provided	0	0	24	41	7	70
Autosomal recessive osteopetrosis 2	3	1	22	2	7	35
Inborn genetic diseases	0	0	10	0	0	10
TNFSF11-related disorder	0	0	0	3	0	3
Increased bone mineral density	0	0	1	0	1	2
Abnormal esophagus morphology	0	0	0	1	0	1
Osteopetrosis	0	0	1	0	0	1
not specified	0	0	1	0	0	1

Submitter and significance breakdown #

Total submitters: 14

Download table as spreadsheet

Submitter	pathogenic	likely pathogenic	uncertain significance	likely benign	benign	total
Labcorp Genetics (formerly Invitae), Labcorp	0	0	22	41	2	65
Illumina Laboratory Services, Illumina	0	0	22	2	7	31
Ambry Genetics	0	0	10	0	0	10
Breakthrough Genomics, Breakthrough Genomics	0	0	0	1	4	5
Eurofins Ntd Llc (ga)	0	0	4	0	0	4
GeneDx	0	0	0	0	3	3
PreventionGenetics, part of Exact Sciences	0	0	0	3	0	3
OMIM	2	0	0	0	0	2
Genome Diagnostics Laboratory, The Hospital for Sick Children	0	0	1	0	1	2
Women's Health and Genetics/Laboratory Corporation of America, LabCorp	0	0	1	0	0	1
Clinical Genetics, Erasmus University Medical Center	0	0	0	1	0	1
3billion	0	1	0	0	0	1
Neuberg Centre For Genomic Medicine, NCGM	0	0	1	0	0	1
Molecular Lab, Department of Haematology, Christian Medical College	1	0	0	0	0	1

The information on this website is not intended for direct diagnostic use or medical decision-making without review by a genetics professional. Individuals should not change their health behavior solely on the basis of information contained on this website. Neither the University of Utah nor the National Institutes of Health independently verfies the submitted information. If you have questions about the information contained on this website, please see a health care professional.