Variants in gene TOP1MT - ClinVar Miner

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

If a variant has more than one submission, it may be counted in more than one significance column. If this is the case, the total number of variants will be less than the sum of the other cells.

pathogenic	likely pathogenic	uncertain significance	likely benign	benign	total
0	0	155	81	31	262

Condition and significance breakdown #

Total conditions: 3

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Condition	uncertain significance	likely benign	benign	total
not provided	92	76	31	197
not specified	71	5	0	76
Sensorineural hearing loss disorder; Premature ovarian insufficiency	1	0	0	1

Submitter and significance breakdown #

Total submitters: 6

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Submitter	uncertain significance	likely benign	benign	total
Labcorp Genetics (formerly Invitae), Labcorp	92	73	31	196
Ambry Genetics	71	5	0	76
Breakthrough Genomics, Breakthrough Genomics	2	4	13	19
CeGaT Center for Human Genetics Tuebingen	0	4	1	5
GeneDx	0	0	1	1
Reproductive Development, Murdoch Childrens Research Institute	1	0	0	1

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