If a variant has more than one submission, it may be counted in more than one significance column. If this is the
case, the total number of variants will be less than the sum of the other cells.
pathogenic |
likely pathogenic |
uncertain significance |
likely benign |
benign |
other |
not provided |
total |
25
|
43
|
92
|
5
|
175
|
2
|
1
|
343
|
Gene and significance breakdown #
Total genes and gene combinations: 257
Gene or gene combination |
pathogenic |
likely pathogenic |
uncertain significance |
likely benign |
benign |
other |
not provided |
total |
intergenic
|
0 |
0 |
0 |
0 |
44
|
0 |
0 |
44
|
FMR1
|
9
|
3
|
9
|
2
|
6
|
2
|
0 |
31
|
IGSF10
|
0 |
0 |
4
|
0 |
0 |
0 |
0 |
4
|
MCM9
|
2
|
0 |
0 |
1
|
0 |
0 |
1
|
4
|
RYR3
|
0 |
1
|
2
|
0 |
0 |
0 |
0 |
3
|
CYP2E1, LOC110599585, LOC126861107, LOC129390242, LOC130005033, LOC130005034, LOC130005035, LOC130005036, SCART1, SYCE1
|
0 |
1
|
0 |
0 |
1
|
0 |
0 |
2
|
FMR1, FRAXA, LOC107032825, LOC129929053
|
2
|
0 |
0 |
0 |
0 |
0 |
0 |
2
|
LRRC41, RAD54L
|
0 |
2
|
0 |
0 |
0 |
0 |
0 |
2
|
NOBOX
|
0 |
1
|
0 |
0 |
1
|
0 |
0 |
2
|
NOS3
|
0 |
2
|
0 |
0 |
0 |
0 |
0 |
2
|
AADAC, AADACL2
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
AATF, ACACA, C17orf78, DDX52, DHRS11, DUSP14, GGNBP2, HNF1B, LHX1, MRM1, MYO19, PIGW, SYNRG, TADA2A, ZNHIT3
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
ABCC4
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
ACACB, UNG
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
ACAT1, CUL5, RAB39A, SLC35F2, SLN
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
ACKR3
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
ACSL4, AGTR2, AKAP14, ALG13, AMMECR1, AMOT, ARL13A, ARMCX1, ARMCX2, ARMCX3, ARMCX4, ARMCX5, ARMCX5-GPRASP2, ARMCX6, ATG4A, ATP1B4, BEX1, BEX2, BEX3, BEX4, BEX5, BTK, C1GALT1C1, CAPN6, CENPI, CHRDL1, CLDN2, COL4A5, COL4A6, CSTF2, CT47A1, CT47A10, CT47A11, CT47A12, CT47A2, CT47A3, CT47A4, CT47A5, CT47A6, CT47A7, CT47A8, CT47A9, CT47B1, CT83, CUL4B, DANT2, DCX, DNAAF6, DOCK11, DRP2, ESX1, FAM199X, FRMPD3, GLA, GLUD2, GPRASP1, GPRASP2, GPRASP3, GUCY2F, H2BW1, H2BW2, HNRNPH2, HTR2C, IL13RA1, IL13RA2, IL1RAPL2, IRS4, KCNE5, KIAA1210, KLHL13, LAMP2, LHFPL1, LONRF3, LRCH2, LUZP4, MCTS1, MID2, MIR448, MORC4, MORF4L2, NDUFA1, NKAP, NKRF, NOX1, NRK, NUP62CL, NXF2, NXF2B, NXF3, NXF5, NXT2, PAK3, PGRMC1, PLP1, PLS3, PRPS1, PSMD10, PWWP3B, RAB40A, RAB40AL, RAB9B, RADX, RBM41, RBMXL3, RHOXF1, RHOXF2, RHOXF2B, RIPPLY1, RNF113A, RNF128, RPL36A, RPL36A-HNRNPH2, RPL39, RTL4, RTL9, SEPTIN6, SERPINA7, SLC25A43, SLC25A5, SLC25A53, SLC6A14, SOWAHD, STEEP1, SYTL4, TAF7L, TBC1D8B, TCEAL1, TCEAL2, TCEAL3, TCEAL4, TCEAL5, TCEAL6, TCEAL7, TCEAL8, TCEAL9, TCP11X2, TEX13A, TEX13B, TIMM8A, TMEM164, TMEM255A, TMEM31, TMEM35A, TMSB15A, TMSB15B, TRMT2B, TRPC5, TRPC5OS, TSC22D3, UBE2A, UPF3B, VSIG1, WDR44, XKRX, ZBTB33, ZCCHC12, ZCCHC18, ZMAT1
|
1
|
0 |
0 |
0 |
0 |
0 |
0 |
1
|
ADAMTS1
|
0 |
1
|
0 |
0 |
0 |
0 |
0 |
1
|
ADAMTS5
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
ADAMTS6
|
0 |
1
|
0 |
0 |
0 |
0 |
0 |
1
|
ADAMTSL3, AP3B2, BNC1, BTBD1, C15orf40, CPEB1, FSD2, HOMER2, RAMAC, SCARNA15, SH3GL3, TM6SF1, WHAMM
|
0 |
1
|
0 |
0 |
0 |
0 |
0 |
1
|
ADCY5, SEC22A
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
ADGB, ADGB-DT, GRM1, LOC114004398, LOC129997388, RAB32
|
1
|
0 |
0 |
0 |
0 |
0 |
0 |
1
|
ADORA2A, AIFM3, ARVCF, BCR, C22orf15, C22orf39, CABIN1, CCDC116, CDC45, CHCHD10, CLDN5, CLTCL1, COMT, CRKL, CRYBB2, CRYBB3, DDT, DDTL, DERL3, DGCR2, DGCR6, DGCR6L, DGCR8, DRICH1, ESS2, FAM230A, GGT1, GGT2, GGT5, GGTLC2, GGTLC3, GNAZ, GNB1L, GP1BB, GSC2, GSTT1, GSTT2, GSTT2B, GUCD1, HIC2, HIRA, IGLC1, IGLL1, IGLL5, KIAA1671, KLHL22, LHFPL7, LRRC75B, LZTR1, MAPK1, MED15, MIF, MIR130B, MMP11, MRPL40, P2RX6, PI4KA, PIWIL3, PPIL2, PPM1F, PRAME, PRODH, RAB36, RANBP1, RGL4, RIMBP3, RIMBP3B, RIMBP3C, RSPH14, RTL10, RTN4R, SCARF2, SDF2L1, SEPTIN5, SERPIND1, SGSM1, SLC25A1, SLC2A11, SLC7A4, SMARCB1, SNAP29, SNRPD3, SPECC1L, SUSD2, TANGO2, TBX1, THAP7, TMEM191B, TMEM191C, TOP3B, TRMT2A, TSSK2, TXNRD2, UBE2L3, UFD1, UPB1, USP41, VPREB1, VPREB3, YDJC, YPEL1, ZDHHC8, ZNF280A, ZNF280B, ZNF70, ZNF74
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
AFDN, FRMD1, KIF25
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
AFF2
|
0 |
1
|
0 |
0 |
0 |
0 |
0 |
1
|
AFP
|
0 |
1
|
0 |
0 |
0 |
0 |
0 |
1
|
AGAP10, ANXA8L1, NPY4R
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
AGBL4, AGBL4-IT1, BEND5, LOC129930503
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
AK3, CD274, CDC37L1, GLIS3, INSL4, INSL6, JAK2, MIR101-2, PDCD1LG2, PLGRKT, PLPP6, RCL1, RLN1, RLN2, SLC1A1, SPATA6L
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
ALMS1, LOC126806252, NAT8
|
1
|
0 |
0 |
0 |
0 |
0 |
0 |
1
|
AMACR, C1QTNF3, RAI14
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
AMY1A, AMY1B, AMY1C, AMY2A, AMY2B
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
ANKRD30B
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
ANKRD34A, ANKRD35, HJV, ITGA10, LIX1L, NBPF10, NOTCH2NLA, NUDT17, PDE4DIP, PEX11B, PIAS3, POLR3C, POLR3GL, RBM8A, RNF115, TXNIP
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
ANKS1B, BLTP3B
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
AOPEP, FANCC
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
AOX1, BZW1, C2orf69, CLK1, FTCDNL1, HYCC2, KCTD18, MAIP1, NIF3L1, ORC2, PPIL3, SATB2, SGO2, SPATS2L, TYW5
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
APBA2, ENTREP2, GOLGA8M, NSMCE3, TJP1
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
APP, CYYR1
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
AR, OPHN1
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
ARFGAP3, LOC112695101, LOC112695102, LOC121627947, LOC121627948, LOC121853045, LOC125446250, LOC125446253, LOC130067617, LOC130067618, LOC130067619, LOC130067620, LOC130067621, LOC130067622, LOC130067623, LOC130067624, LOC130067625, LOC130067626, PACSIN2, TTLL1
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
ARPP21
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
ASAP1, CYRIB
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
ASB7, CERS3, LINS1
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
ASPHD1, CDIPT, KCTD13, KIF22, MAZ, MVP, PAGR1, PRRT2, SEZ6L2, TMEM219, ZG16
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
ASTN2, LOC107987014, LOC113839502, LOC126860747, LOC130002464, LOC130002465, LOC130002466, LOC132089661, LOC132089662, TRIM32
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
ATG2A
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
ATG7
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
ATG9B
|
0 |
1
|
0 |
0 |
0 |
0 |
0 |
1
|
B3GAT1-DT
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
B3GNT5, MCF2L2
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
BBS9
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
BCO1, PKD1L2
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
BICRA
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
BICRA, EHD2, LOC121627883, LOC125371540, LOC130064814, LOC130064815, LOC130064816, LOC130064817, LOC130064818, LOC130064819, LOC130064820, LOC130064821, LOC130064822, LOC130064823, LOC130064824, LOC130064825, LOC130064826, LOC130064827, LOC130064828, LOC130064829, LOC130064830, NOP53, SELENOW, SNORD23, ZNF541
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
BLK, C8orf74, CLDN23, CTSB, DEFB130A, DEFB134, DEFB135, DEFB136, ERI1, FAM167A, FAM86B1, FDFT1, GATA4, MFHAS1, MIR124-1, MSRA, MTMR9, NEIL2, PINX1, PPP1R3B, PRSS51, PRSS55, RP1L1, SLC35G5, SOX7, TNKS, USP17L2, USP17L7, XKR6, ZNF705D
|
1
|
0 |
0 |
0 |
0 |
0 |
0 |
1
|
BMAL1
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
BMP6
|
0 |
1
|
0 |
0 |
0 |
0 |
0 |
1
|
BNC1
|
0 |
1
|
0 |
0 |
0 |
0 |
0 |
1
|
BRD3
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
BRDT
|
1
|
0 |
0 |
0 |
0 |
0 |
0 |
1
|
BRWD1
|
0 |
1
|
0 |
0 |
0 |
0 |
0 |
1
|
C1QTNF6, IL2RB, SSTR3, TMPRSS6
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
C1QTNF9B, MIPEP, PCOTH, SACS, SGCG, SPATA13, TNFRSF19
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
C1orf87, CYP2J2, FGGY, HOOK1
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
C3
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
CADM2
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
CCDC115
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
CD99, GYG2, LOC126863189, XG
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
CDH19
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
CDRT15, CDRT4, COX10, HS3ST3B1, PMP22, TEKT3, TVP23C-CDRT4
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
CENPL, DARS2, GAS5, KLHL20, RC3H1, SERPINC1, ZBTB37
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
CENPP, LOC132089711, LOC132089712, NOL8, OGN, OMD
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
CFH, CFHR1, CFHR3, CFHR4, LOC122149335, LOC126805964
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
CFHR1, CFHR4
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
CGNL1
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
CHD7
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
CHEK2
|
1
|
0 |
0 |
0 |
0 |
0 |
0 |
1
|
CHL1, CNTN4, CNTN6
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
CHN2
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
CHRNA7
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
CHST11
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
CHST5, TMEM231
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
CHSY1, LOC125146369, LOC125146370, LOC130058064, LOC130058065, LOC130058066, LOC130058067, LOC130058068, LOC130058069, LOC130058070, LOC130058071, LOC130058072, LRRK1, SELENOS, SNRPA1
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
CLEC4C, NANOG, NANOGNB, SLC2A14
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
CLNK, ZNF518B
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
COL26A1
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
CSMD3, LOC126860474, MIR2053
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
CST4
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
CT45A1, CT55, INTS6L, ZNF449, ZNF75D
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
CTNNA3, LOC132089819
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
CYLC2
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
CYP17A1
|
0 |
1
|
0 |
0 |
0 |
0 |
0 |
1
|
CYP19A1, MIR4713HG, PIRC66
|
0 |
1
|
0 |
0 |
0 |
0 |
0 |
1
|
CYP2C19, LOC110599570, LOC111982881
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
DDX11
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
DDX53, LOC126863227, PTCHD1
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
DEFB134, DEFB135, DEFB136
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
DGCR2, DGCR6, PRODH
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
DGCR6L, FAM230A, GGTLC3, KLHL22, MED15, RIMBP3, RTN4R, SCARF2, TMEM191B, USP41, ZNF74
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
DLEU7, LOC121838575, LOC130009802, LOC130009803, LOC130009804, LOC130009805, LOC130009806, LOC130009807, LOC130009808
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
DMC1
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
DMD
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
DMRT3
|
0 |
1
|
0 |
0 |
0 |
0 |
0 |
1
|
DNAH11, SP4
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
DNAH6
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
DOC2B, LINC02091, LOC132090892, RPH3AL
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
DOCK8
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
DOCK8, FOXD4, ZNG1A
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
DPPA2
|
0 |
1
|
0 |
0 |
0 |
0 |
0 |
1
|
DPY19L2
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
DPY19L2, LOC130008194
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
EFL1, SAXO2
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
EHF
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
ERCC4
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
FAM120B, PDCD2, PSMB1, TBP
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
FANCA
|
0 |
1
|
0 |
0 |
0 |
0 |
0 |
1
|
FHIT
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
FIGLA
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
FMN2, LOC126806069
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
FMR1, FRAXA, LOC107032825
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
FMR1, LOC107032825
|
0 |
0 |
0 |
1
|
0 |
0 |
0 |
1
|
FPR2, FPR3, ZNF350, ZNF432, ZNF577, ZNF613, ZNF614, ZNF615, ZNF649, ZNF841
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
FYN
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
GALT
|
1
|
0 |
0 |
0 |
0 |
0 |
0 |
1
|
GDF9
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
GK2, NAA11
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
GLI1
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
GOLGA8B
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
GOLPH3, LOC126807344, PDZD2
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
GPR141
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
GPR17, LIMS2, MYO7B
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
GRAMD1C
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
GTF2H2C, LOC101928924, MARVELD2, OCLN, SNORD13B-1
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
HAPSTR1
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
HS6ST3, MIR4501
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
IGF2R
|
0 |
1
|
0 |
0 |
0 |
0 |
0 |
1
|
IGH, IGHA1, IGHD, IGHD3-3, IGHG1, IGHG3, IGHM, IGHV3-23
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
IMMP2L, LOC129389845
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
INHA
|
0 |
0 |
0 |
1
|
0 |
0 |
0 |
1
|
INSL6, JAK2
|
1
|
0 |
0 |
0 |
0 |
0 |
0 |
1
|
KANSL1
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
KCNIP3, MAL, MRPS5, PROM2, TEKT4, ZNF2, ZNF514
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
KCNN2
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
KCNQ5, KHDC1L, LOC113175017, LOC122539213, LOC126859710
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
KDR
|
0 |
1
|
0 |
0 |
0 |
0 |
0 |
1
|
KHDRBS1
|
0 |
1
|
0 |
0 |
0 |
0 |
0 |
1
|
LARS2
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
LEPR
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
LINC00871
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
LINC01237, LINC01238, LINC01880, LINC01881, LINC03100, LOC122889016, LOC132205954, LOC285097
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
LINC01541
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
LINC02018, LOC112935961, LOC129937069, LOC129937070, LOC129937071, LOC129937072, LOC129937073
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
LINC02055
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
LINC02374, LOC339975
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
LINC02714
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
LINC02743, SPATA19
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
LINC02907
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
LINGO2
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
LOC105379224, LOC124049159, LOC126860297, LOC129999814, LOC129999815, LOC129999816, LOC129999817, LOC129999818, LOC129999819
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
LOC106780824, LOC125424402, LOC130067127, LOC130067128, LOC130067129, LOC130067130, LOC130067131, LOC130067132, LOC130067133, LOC130067134, MIR6817
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
LOC110121330
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
LOC113687185
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
LOC116268429, LOC116268430, LOC116268431, LOC124625898, LOC126861438, LOC129390395, LOC130007317, LOC130007318, SLC2A14, SLC2A3
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
LOC116276448, LOC126862291
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
LOC122056898, MIR12132, PATJ
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
LOC122094904, LOC129931240, SYT6
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
LOC122756690
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
LOC122861256, OSBPL6
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
LOC125371453, LOC129391033, LOC130063167, ZFR2
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
LOC126805813
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
LOC126807223, SPATA4, WDR17
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
LOC126860076
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
LOC126861571
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
LOC126861930
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
LOC129390101, LOC129390102
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
LOC129390953
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
LOC129994273, LOC129994274, LOC129994275, LOC129994276
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
LOC129997635, LOC129997636, PRKN
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
LOC129997800, LOC129997801, LOC129997802, LOC129997803, LOC129997804, LOC129997805, LOC129997806, LOC129997807, LOC129997808, LOC129997809, SNX8
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
LOC130003769
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
LOC130065435, LOC130065436, MACROD2
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
LOC132089650, PTGR1, ZNF483
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
LOC132090156, MIR1267, NALF1
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
LOC132090486
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
LRP2
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
LSM14A
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
MAP3K4
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
MARCHF4, MREG, PECR, TMEM169, XRCC5
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
MECOM
|
0 |
1
|
0 |
0 |
0 |
0 |
0 |
1
|
MLH3
|
0 |
1
|
0 |
0 |
0 |
0 |
0 |
1
|
MND1
|
0 |
1
|
0 |
0 |
0 |
0 |
0 |
1
|
MOV10
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
MRPS22
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
MSR1
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
MT1HL1, RYR2
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
MYC
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
NCAM2
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
NCKAP5
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
NLGN1
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
NOTCH2
|
0 |
1
|
0 |
0 |
0 |
0 |
0 |
1
|
NR5A2
|
0 |
1
|
0 |
0 |
0 |
0 |
0 |
1
|
NTRK1
|
0 |
1
|
0 |
0 |
0 |
0 |
0 |
1
|
OR4A15, OR4C11, OR4C15, OR4C16, OR4C6, OR4P4, OR4S2
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
OR4F15, OR4F6, TARS3
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
OR4K1, OR4K2, OR4K5, OR4M1, OR4N2, OR4Q3
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
OR8J1
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
PADI6
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
PARD3
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
PARP4
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
PFKP, PITRM1, SNORD142
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
PLD5
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
PMM2
|
1
|
0 |
0 |
0 |
0 |
0 |
0 |
1
|
PNPLA4, PUDP, STS, VCX
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
PNPLA7
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
POLG
|
0 |
1
|
0 |
0 |
0 |
0 |
0 |
1
|
POR
|
0 |
1
|
0 |
0 |
0 |
0 |
0 |
1
|
POTEB
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
PPP4R1, RALBP1
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
PRIM1
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
PRKD1
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
PRLR
|
0 |
1
|
0 |
0 |
0 |
0 |
0 |
1
|
PSG1, PSG11, PSG6, PSG7
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
PWRN2
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
RAB19, SLC37A3
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
RAD51C
|
0 |
1
|
0 |
0 |
0 |
0 |
0 |
1
|
RAD54L
|
1
|
0 |
0 |
0 |
0 |
0 |
0 |
1
|
REC8
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
REST
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
RICTOR
|
0 |
1
|
0 |
0 |
0 |
0 |
0 |
1
|
RIMS2
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
SCARB1
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
SEMA5A, TAS2R1
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
SFPQ, ZMYM1
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
SGO2
|
1
|
0 |
0 |
0 |
0 |
0 |
0 |
1
|
SH2B1
|
0 |
1
|
0 |
0 |
0 |
0 |
0 |
1
|
SIRT6
|
0 |
1
|
0 |
0 |
0 |
0 |
0 |
1
|
SLC24A2
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
STAG3
|
1
|
0 |
0 |
0 |
0 |
0 |
0 |
1
|
TCERG1L
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
TG
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
THBS1
|
0 |
1
|
0 |
0 |
0 |
0 |
0 |
1
|
TMEM132D
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
TOP3B
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
TRIML1, TRIML2, ZFP42
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
TSPAN7
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
UGT2B15
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
WHAMM
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
WT1
|
0 |
1
|
0 |
0 |
0 |
0 |
0 |
1
|
WWOX
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
XPNPEP2
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
ZNF462
|
0 |
1
|
0 |
0 |
0 |
0 |
0 |
1
|
ZNF626
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
ZNF630
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
ZNF716
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
ZNF92
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
Submitter and significance breakdown #
Submitter |
pathogenic |
likely pathogenic |
uncertain significance |
likely benign |
benign |
other |
not provided |
total |
Department of Biotechnology, Institute of Molecular and Cell Biology, University of Tartu
|
3
|
2
|
50
|
0 |
165
|
0 |
0 |
220
|
Medical Cytogenetics and Molecular Genetics Laboratory, IRCCS Istituto Auxologico Italiano
|
7
|
37
|
20
|
0 |
0 |
0 |
0 |
64
|
Lupski Lab, Baylor-Hopkins CMG, Baylor College of Medicine
|
0 |
1
|
10
|
1
|
1
|
0 |
0 |
13
|
OMIM
|
5
|
0 |
0 |
0 |
0 |
0 |
0 |
5
|
Natera, Inc.
|
0 |
0 |
0 |
1
|
4
|
0 |
0 |
5
|
American College of Medical Genetics and Genomics (ACMG)
|
1
|
0 |
0 |
0 |
1
|
2
|
0 |
4
|
Fulgent Genetics, Fulgent Genetics
|
0 |
0 |
1
|
1
|
2
|
0 |
0 |
4
|
Mendelics
|
0 |
0 |
0 |
1
|
2
|
0 |
0 |
3
|
Rajkovic Lab, University of Pittsburgh
|
2
|
0 |
0 |
0 |
0 |
0 |
1
|
3
|
Baylor Genetics
|
0 |
1
|
1
|
0 |
0 |
0 |
0 |
2
|
Elsea Lab, Dept of Molecular and Human Genetics, Baylor College of Medicine
|
2
|
0 |
0 |
0 |
0 |
0 |
0 |
2
|
Rare Disease Group, Clinical Genetics, Karolinska Institutet
|
0 |
0 |
2
|
0 |
0 |
0 |
0 |
2
|
Broad Center for Mendelian Genomics, Broad Institute of MIT and Harvard
|
0 |
0 |
0 |
1
|
1
|
0 |
0 |
2
|
Department Of Genetics, Sultan Qaboos University Hospital, Sultan Qaboos University
|
2
|
0 |
0 |
0 |
0 |
0 |
0 |
2
|
Victorian Clinical Genetics Services, Murdoch Childrens Research Institute
|
1
|
0 |
0 |
0 |
0 |
0 |
0 |
1
|
Genomic Medicine Center of Excellence, King Faisal Specialist Hospital and Research Centre
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
Illumina Laboratory Services, Illumina
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
Institute for Human Genetics and Genomic Medicine, Uniklinik RWTH Aachen
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
Laboratory of Molecular Genetics, National Institutes of Health
|
1
|
0 |
0 |
0 |
0 |
0 |
0 |
1
|
MIND Institute, Wet lab, University of California Davis
|
1
|
0 |
0 |
0 |
0 |
0 |
0 |
1
|
Centre for Mendelian Genomics, University Medical Centre Ljubljana
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
Genetics and Molecular Pathology, SA Pathology
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
Institute of Human Genetics, University of Leipzig Medical Center
|
1
|
0 |
0 |
0 |
0 |
0 |
0 |
1
|
Laboratory of Medical Genetics, University of Torino
|
0 |
1
|
0 |
0 |
0 |
0 |
0 |
1
|
Institute of Human Genetics, University Hospital Muenster
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
New York Genome Center
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
Genetics Laboratory, UDIAT-Centre Diagnòstic, Hospital Universitari Parc Tauli
|
0 |
1
|
0 |
0 |
0 |
0 |
0 |
1
|
Neuberg Centre For Genomic Medicine, NCGM
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
MVZ Medizinische Genetik Mainz
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
The information on this website is not intended for direct
diagnostic use or medical decision-making without review by a
genetics professional. Individuals should not change their
health behavior solely on the basis of information contained on
this website. Neither the University of Utah nor the National
Institutes of Health independently verfies the submitted
information. If you have questions about the information
contained on this website, please see a health care
professional.