If a variant has more than one submission, it may be counted in more than one significance column. If this is the case, the total number of variants will be less than the sum of the other cells.
pathogenic | likely pathogenic | uncertain significance | likely benign | benign | association | not provided | total |
---|---|---|---|---|---|---|---|
9 | 31 | 6 | 6 | 0 | 1 | 7 | 58 |
Gene and significance breakdown #
Gene or gene combination | pathogenic | likely pathogenic | uncertain significance | likely benign | association | not provided | total |
---|---|---|---|---|---|---|---|
ABL1 | 2 | 26 | 0 | 5 | 1 | 1 | 33 |
BCR | 0 | 0 | 4 | 1 | 0 | 2 | 7 |
CSF3R | 0 | 2 | 0 | 0 | 0 | 0 | 2 |
NRAS | 1 | 1 | 0 | 0 | 0 | 0 | 2 |
TET2 | 1 | 0 | 1 | 0 | 0 | 0 | 2 |
ASXL1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 |
BCR, LOC107963955 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
BRAF | 0 | 1 | 0 | 0 | 0 | 0 | 1 |
FLT3, MYO18A | 0 | 1 | 0 | 0 | 0 | 0 | 1 |
IKZF1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 |
INSL6, JAK2 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
KIT | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
KRAS | 1 | 0 | 0 | 0 | 0 | 0 | 1 |
MFSD11, SRSF2 | 1 | 0 | 0 | 0 | 0 | 0 | 1 |
RUNX1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 |
SETBP1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
SF3B1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 |
Submitter and significance breakdown #
Submitter | pathogenic | likely pathogenic | uncertain significance | likely benign | association | not provided | total |
---|---|---|---|---|---|---|---|
Database of Curated Mutations (DoCM) | 0 | 30 | 0 | 0 | 0 | 4 | 34 |
Fulgent Genetics, Fulgent Genetics | 0 | 0 | 0 | 6 | 0 | 0 | 6 |
Institute of Laboratory Medicine, Hospital Wels-Grieskirchen | 4 | 0 | 1 | 0 | 0 | 0 | 5 |
Druker Lab, Oregon Health and Sciences University | 3 | 0 | 1 | 0 | 0 | 0 | 4 |
Laboratory of Molecular Diagnostics and Monitoring of CML and Ph+ Leukemias, Institute of Hematology and Blood Transfusion | 0 | 0 | 0 | 0 | 0 | 3 | 3 |
Center for Genomics, Ann and Robert H. Lurie Children's Hospital of Chicago | 0 | 0 | 3 | 0 | 0 | 0 | 3 |
OMIM | 2 | 0 | 0 | 0 | 0 | 0 | 2 |
Knight Cancer Institute, Oregon Health and Science University | 0 | 1 | 0 | 0 | 0 | 0 | 1 |
Al Jalila Children's Genomics Center, Al Jalila Childrens Speciality Hospital | 0 | 0 | 1 | 0 | 0 | 0 | 1 |
3billion | 0 | 1 | 0 | 0 | 0 | 0 | 1 |
KCCC/NGS Laboratory, Kuwait Cancer Control Center | 0 | 0 | 0 | 0 | 1 | 0 | 1 |