ClinVar Miner

Variants studied for breast-ovarian cancer, familial, susceptibility to, 3

Included ClinVar conditions (2):
Minimum submission review status: Collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than one submission, it may be counted in more than one significance column. If this is the case, the total number of variants will be less than the sum of the other cells.

pathogenic likely pathogenic uncertain significance likely benign benign risk factor not provided total
125 104 221 47 12 7 7 461

Gene and significance breakdown #

Total genes and gene combinations: 6
Download table as spreadsheet
Gene or gene combination pathogenic likely pathogenic uncertain significance likely benign benign risk factor not provided total
RAD51C 109 92 202 40 12 7 6 412
LOC129390903, RAD51C 16 8 18 4 0 0 1 42
LOC130061310, RAD51C 0 3 1 1 0 0 0 4
RAD51C, TEX14 0 1 0 0 0 0 0 1
RAD51D, RAD51L3-RFFL 0 0 0 1 0 0 0 1
TP53 0 0 0 1 0 0 0 1

Submitter and significance breakdown #

Total submitters: 35
Download table as spreadsheet
Submitter pathogenic likely pathogenic uncertain significance likely benign benign risk factor not provided total
Baylor Genetics 30 41 149 0 0 0 0 220
Myriad Genetics, Inc. 94 61 12 16 9 0 0 192
Fulgent Genetics, Fulgent Genetics 11 7 47 12 0 0 0 77
Counsyl 9 7 29 14 5 0 0 63
Hereditary Cancer Group, L’Institut d'Investigació Biomèdica de Bellvitge 16 10 18 4 0 0 0 48
KCCC/NGS Laboratory, Kuwait Cancer Control Center 0 1 15 0 6 0 0 22
Illumina Laboratory Services, Illumina 0 0 9 3 1 0 0 13
Institute of Human Genetics, University of Leipzig Medical Center 5 2 5 1 0 0 0 13
St. Jude Molecular Pathology, St. Jude Children's Research Hospital 1 1 6 0 0 0 0 8
BRCAlab, Lund University 8 0 0 0 0 0 0 8
OMIM 0 0 0 0 0 7 0 7
MGZ Medical Genetics Center 2 2 2 0 0 0 0 6
Department of Molecular Diagnostics, Institute of Oncology Ljubljana 2 1 2 1 0 0 0 6
Genetics and Molecular Pathology, SA Pathology 1 0 3 1 0 0 0 5
Department of Pathology and Laboratory Medicine, Sinai Health System 3 1 1 0 0 0 0 5
GenomeConnect - Invitae Patient Insights Network 0 0 0 0 0 0 5 5
Centre for Mendelian Genomics, University Medical Centre Ljubljana 3 0 0 0 0 0 0 3
Division of Medical Genetics, University of Washington 0 1 2 0 0 0 0 3
Neuberg Centre For Genomic Medicine, NCGM 0 0 3 0 0 0 0 3
Department of Human Genetics, Hannover Medical School 2 1 0 0 0 0 0 3
Center for Genomic Medicine, King Faisal Specialist Hospital and Research Center 0 0 0 0 2 0 0 2
Laboratoire de Biologie et Génétique du Cancer, Centre François Baclesse 2 0 0 0 0 0 0 2
GenomeConnect, ClinGen 0 0 0 0 0 0 2 2
Center for Genomics, Ann and Robert H. Lurie Children's Hospital of Chicago 0 0 2 0 0 0 0 2
University of Washington Department of Laboratory Medicine, University of Washington 0 1 0 1 0 0 0 2
Dr. med. U. Finckh, Human Genetics, Eurofins MVZ 0 1 1 0 0 0 0 2
Greenwood Genetic Center Diagnostic Laboratories, Greenwood Genetic Center 1 0 0 0 0 0 0 1
Genetic Services Laboratory, University of Chicago 1 0 0 0 0 0 0 1
Department of Obstetrics and Gynecology, Helsinki University Hospital 0 1 0 0 0 0 0 1
Juno Genomics, Hangzhou Juno Genomics, Inc 0 1 0 0 0 0 0 1
UNC Molecular Genetics Laboratory, University of North Carolina at Chapel Hill 1 0 0 0 0 0 0 1
Lifecell International Pvt. Ltd 0 1 0 0 0 0 0 1
Human Genetics Bochum, Ruhr University Bochum 0 1 0 0 0 0 0 1
Laboratorio de Genetica e Diagnostico Molecular, Hospital Israelita Albert Einstein 0 0 1 0 0 0 0 1
Institute of Immunology and Genetics Kaiserslautern 1 0 0 0 0 0 0 1

The information on this website is not intended for direct diagnostic use or medical decision-making without review by a genetics professional. Individuals should not change their health behavior solely on the basis of information contained on this website. Neither the University of Utah nor the National Institutes of Health independently verfies the submitted information. If you have questions about the information contained on this website, please see a health care professional.