ClinVar Miner

Variants studied for papillary renal cell carcinoma

Included ClinVar conditions (4):
Minimum submission review status: Collection method:
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Gene type:
ClinVar version:

If a variant has more than one submission, it may be counted in more than one significance column. If this is the case, the total number of variants will be less than the sum of the other cells.

pathogenic likely pathogenic uncertain significance likely benign benign other not provided total
12 105 165 41 65 1 1 378

Gene and significance breakdown #

Total genes and gene combinations: 22
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Gene or gene combination pathogenic likely pathogenic uncertain significance likely benign benign other not provided total
MET 8 1 152 40 64 0 1 254
TP53 0 61 0 0 0 0 0 61
MTOR 1 9 0 1 0 0 0 11
PIK3CA 0 10 0 0 0 0 0 10
COMETT, MET 0 0 7 0 1 0 0 8
LOC107303340, VHL 2 3 0 0 0 0 0 5
NRAS 0 5 0 0 0 0 0 5
NFE2L2 0 4 0 0 0 0 0 4
PTEN 0 4 0 0 0 0 0 4
ELOC 0 3 0 0 0 0 0 3
RHEB 0 2 0 0 0 0 0 2
ASZ1, CAPZA2, CFTR, LOC111365177, LOC111674463, LOC111674464, LOC111674465, LOC111674466, LOC111674476, LOC111674478, LOC113219431, LOC113219432, LOC113219433, LOC113219434, LOC113219439, LOC113219440, LOC113219442, LOC113219443, LOC113219444, LOC113219445, LOC113219446, LOC113219447, LOC116186911, LOC123956215, LOC126860157, LOC126860158, LOC126860159, LOC129999177, LOC129999178, LOC129999179, LOC129999180, LOC129999181, LOC129999182, LOC129999183, LOC129999184, LOC129999185, LOC129999186, LOC129999187, LOC129999188, MET, MIR6132, ST7, ST7-OT3, ST7-OT4, WNT2 0 0 1 0 0 0 0 1
ASZ1, CAPZA2, CFTR, MET, RNU2-1, ST7, ST7-OT3, ST7-OT4, WNT2 0 0 1 0 0 0 0 1
ATM, C11orf65 1 0 0 0 0 0 0 1
CTNNB1, LOC126806659 0 0 0 0 0 1 0 1
LOC111365177, LOC113219432, LOC126860158, MET 0 0 1 0 0 0 0 1
MSH2 0 0 1 0 0 0 0 1
PRCC 0 0 1 0 0 0 0 1
SDHB 0 0 1 0 0 0 0 1
SF3B1 0 1 0 0 0 0 0 1
SF3B2 0 1 0 0 0 0 0 1
VHL 0 1 0 0 0 0 0 1

Submitter and significance breakdown #

Total submitters: 22
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Submitter pathogenic likely pathogenic uncertain significance likely benign benign other not provided total
Illumina Laboratory Services, Illumina 0 0 67 15 58 0 0 140
Database of Curated Mutations (DoCM) 0 104 0 0 0 0 0 104
Mendelics 2 0 40 18 4 0 0 64
Fulgent Genetics, Fulgent Genetics 0 0 23 1 0 0 0 24
St. Jude Molecular Pathology, St. Jude Children's Research Hospital 0 0 20 0 1 0 0 21
KCCC/NGS Laboratory, Kuwait Cancer Control Center 0 0 0 5 14 0 0 19
Labcorp Genetics (formerly Invitae), Labcorp 0 0 14 3 0 0 0 17
OMIM 9 0 0 0 0 0 0 9
Baylor Genetics 0 0 3 0 0 0 0 3
CSER _CC_NCGL, University of Washington 0 0 2 0 0 0 0 2
Institute of Human Genetics, University of Goettingen 0 0 1 0 0 0 0 1
Institute of Human Genetics, Cologne University 0 0 1 0 0 0 0 1
MGZ Medical Genetics Center 0 0 1 0 0 0 0 1
Donald Williams Parsons Laboratory, Baylor College of Medicine 0 0 0 0 0 1 0 1
Genetics and Molecular Pathology, SA Pathology 0 0 0 0 1 0 0 1
Institute of Human Genetics, University of Leipzig Medical Center 0 0 0 1 0 0 0 1
Cancer medicine, Gaomi People's Hospital 1 0 0 0 0 0 0 1
Myriad Genetics, Inc. 0 1 0 0 0 0 0 1
GenomeConnect - Invitae Patient Insights Network 0 0 0 0 0 0 1 1
Neuberg Centre For Genomic Medicine, NCGM 0 0 1 0 0 0 0 1
Department of Human Genetics, Hannover Medical School 0 0 1 0 0 0 0 1
Laboratorio de Genetica e Diagnostico Molecular, Hospital Israelita Albert Einstein 0 0 1 0 0 0 0 1

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