ClinVar Miner

Variants studied for pancreatic neoplasm

Included ClinVar conditions (36):
Minimum submission review status: Collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than one submission, it may be counted in more than one significance column. If this is the case, the total number of variants will be less than the sum of the other cells.

pathogenic likely pathogenic uncertain significance likely benign benign risk factor not provided total
332 75 1002 352 121 6 4 1869

Gene and significance breakdown #

Total genes and gene combinations: 28
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Gene or gene combination pathogenic likely pathogenic uncertain significance likely benign benign risk factor not provided total
PALLD 0 0 237 117 51 1 0 399
CBR4, PALLD 0 0 250 123 29 0 0 393
BRCA2 130 18 149 28 17 1 1 343
PALB2 46 25 191 38 2 2 2 303
BRCA1 82 8 64 24 18 1 1 196
TP53 15 10 19 5 2 0 0 51
SMAD4 7 3 30 2 0 0 0 42
STK11 5 2 22 6 0 0 0 35
BRCA1, LOC126862571 12 0 16 2 2 0 0 32
KRAS 6 2 13 6 0 0 0 27
GCGR 10 0 1 0 0 0 0 11
ATM 3 0 4 0 0 0 0 7
ATM, C11orf65 3 1 1 0 0 0 0 5
CHEK2 3 1 0 0 0 0 0 4
BARD1 0 0 3 0 0 0 0 3
LOC130062899, STK11 0 0 2 1 0 0 0 3
ACVR1B 2 0 0 0 0 0 0 2
BRIP1 2 0 0 0 0 0 0 2
CDKN2A 0 2 0 0 0 0 0 2
DCTN5, PALB2 1 0 0 0 0 1 0 1
ERCC4 0 1 0 0 0 0 0 1
FANCE 1 0 0 0 0 0 0 1
FANCG 0 1 0 0 0 0 0 1
HOXB13 0 1 0 0 0 0 0 1
MEN1 1 0 0 0 0 0 0 1
NBN 1 0 0 0 0 0 0 1
POLD1 1 0 0 0 0 0 0 1
RBBP8 1 0 0 0 0 0 0 1

Submitter and significance breakdown #

Total submitters: 34
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Submitter pathogenic likely pathogenic uncertain significance likely benign benign risk factor not provided total
Fulgent Genetics, Fulgent Genetics 240 38 514 112 41 0 0 944
Labcorp Genetics (formerly Invitae), Labcorp 0 0 409 217 35 0 0 661
Illumina Laboratory Services, Illumina 0 0 51 15 54 0 0 120
Juno Genomics, Hangzhou Juno Genomics, Inc 39 19 0 0 0 0 0 58
CZECANCA consortium 24 5 0 0 0 0 0 29
OMIM 21 0 0 0 0 6 0 27
KCCC/NGS Laboratory, Kuwait Cancer Control Center 0 0 1 7 15 0 0 23
Department of Pathology and Laboratory Medicine, Sinai Health System 6 1 13 1 0 0 0 21
Leiden Open Variation Database 2 0 8 0 0 0 0 10
Human Genome Sequencing Center Clinical Lab, Baylor College of Medicine 3 3 1 0 0 0 0 7
Centre for Mendelian Genomics, University Medical Centre Ljubljana 2 0 4 0 0 0 0 6
Center for Genomics, Ann and Robert H. Lurie Children's Hospital of Chicago 2 0 3 0 0 0 0 5
Baylor Genetics 0 0 4 0 0 0 0 4
Human Genetics Bochum, Ruhr University Bochum 2 2 0 0 0 0 0 4
Genomic Medicine Center of Excellence, King Faisal Specialist Hospital and Research Centre 1 2 0 0 0 0 0 3
Institute of Human Genetics, University of Leipzig Medical Center 2 1 0 0 0 0 0 3
Department of Human Genetics, Hannover Medical School 2 0 1 0 0 0 0 3
Molecular Genetics and NGS Laboratory, Hospital Fundacion Valle Del Lili 3 0 0 0 0 0 0 3
MGZ Medical Genetics Center 0 1 1 0 0 0 0 2
GenomeConnect, ClinGen 0 0 0 0 0 0 2 2
University of Washington Department of Laboratory Medicine, University of Washington 0 0 0 2 0 0 0 2
GenomeConnect - Invitae Patient Insights Network 0 0 0 0 0 0 2 2
Neuberg Centre For Genomic Medicine, NCGM 0 1 1 0 0 0 0 2
Laboratorio de Genetica e Diagnostico Molecular, Hospital Israelita Albert Einstein 0 0 2 0 0 0 0 2
Ganetzky Laboratory, Children's Hospital of Philadelphia 2 0 0 0 0 0 0 2
Revvity Omics, Revvity 0 0 1 0 0 0 0 1
Clinical Genomics Laboratory, Washington University in St. Louis 1 0 0 0 0 0 0 1
Institute of Human Genetics, University Hospital of Duesseldorf 0 1 0 0 0 0 0 1
Genetics and Molecular Pathology, SA Pathology 1 0 0 0 0 0 0 1
HUSP Clinical Genetics Laboratory, Hospital Universitario San Pedro De Logroño (HUSP) 0 1 0 0 0 0 0 1
Laboratory for Clinical Genomics and Advanced Technology, Dartmouth-Hitchcock Medical Center 1 0 0 0 0 0 0 1
Institute of Human Genetics, Clinical Exome/Genome Diagnostics Group, University Hospital Bonn 1 0 0 0 0 0 0 1
Clinical Genetics Laboratory, University Hospital Schleswig-Holstein 1 0 0 0 0 0 0 1
Institute of Immunology and Genetics Kaiserslautern 0 0 1 0 0 0 0 1

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