ClinVar Miner

Variants studied for low grade astrocytic tumor

Included ClinVar conditions (5):
Minimum submission review status: Collection method:
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Gene type:
ClinVar version:

If a variant has more than one submission, it may be counted in more than one significance column. If this is the case, the total number of variants will be less than the sum of the other cells.

pathogenic likely pathogenic uncertain significance likely benign benign total
5 1 5 0 0 11

Gene and significance breakdown #

Total genes and gene combinations: 10
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Gene or gene combination pathogenic likely pathogenic uncertain significance total
FGFR1 0 0 2 2
AASS, ABCA13, ABCB1, ABCB4, ABCB5, ABHD11, ACHE, ACTL6B, ADAM22, ADCK2, ADCY1, ADCYAP1R1, AEBP1, AGBL3, AGFG2, AGMO, AGR2, AGR3, AHCYL2, AHR, AKAP9, AKR1B1, AKR1B10, AKR1B15, AKR1D1, ALKBH4, AMPH, ANKIB1, ANKMY2, ANKRD7, ANLN, AOAH, AP1S1, AP4M1, AQP1, ARF5, ARL4A, ARMC10, ARPC1A, ARPC1B, ASB15, ASB4, ASL, ASNS, ASZ1, ATP5MF, ATP5MF-PTCD1, ATP6V0A4, ATP6V1F, ATXN7L1, AUTS2, AVL9, AZGP1, BAIAP2L1, BAZ1B, BBS9, BCAP29, BCL7B, BET1, BHLHA15, BLVRA, BMPER, BMT2, BPGM, BRAF, BRI3, BUD23, BUD31, BZW2, C7orf25, C7orf31, C7orf57, C7orf76, CACNA2D1, CADPS2, CALCR, CALD1, CALN1, CALU, CAMK2B, CAPZA2, CASD1, CASTOR2, CAV1, CAV2, CBLL1, CBX3, CCDC126, CCDC136, CCDC146, CCDC71L, CCL24, CCL26, CCM2, CCT6A, CD36, CDCA7L, CDHR3, CDK13, CDK14, CDK6, CEP41, CFAP69, CFTR, CHCHD2, CHCHD3, CHN2, CHRM2, CLDN12, CLDN15, CLDN3, CLDN4, CLEC2L, CLIP2, CNOT4, CNPY4, COA1, COBL, COG5, COL1A2, COL26A1, COPG2, COPS6, CPA1, CPA2, CPA4, CPA5, CPED1, CPSF4, CPVL, CRCP, CREB3L2, CREB5, CRHR2, CROT, CRPPA, CTTNBP2, CUX1, CYCS, CYP3A4, CYP3A43, CYP3A5, CYP3A7, CYP51A1, CYREN, DBF4, DBNL, DDC, DDX56, DENND2A, DGKB, DGKI, DLD, DLX5, DLX6, DMTF1, DNAH11, DNAJB9, DNAJC2, DNAJC30, DOCK4, DPY19L1, DTX2, DUS4L, DYNC1I1, EEPD1, EGFR, EIF4H, ELAPOR2, ELMO1, ELN, EPDR1, EPHB4, EPO, ERV3-1, ERVW-1, ETV1, EVX1, EXOC4, FAM133B, FAM180A, FAM185A, FAM200A, FAM221A, FAM3C, FBXL13, FBXO24, FERD3L, FEZF1, FGL2, FIGNL1, FIS1, FKBP14, FKBP6, FKBP9, FLNC, FMC1, FMC1-LUC7L2, FOXP2, FSCN3, FZD1, FZD9, GAL3ST4, GALNT17, GARIN1A, GARIN1B, GARS1, GATAD1, GCC1, GCK, GGCT, GHRHR, GIGYF1, GJC3, GLI3, GNAI1, GNAT3, GNB2, GNG11, GNGT1, GPC2, GPNMB, GPR141, GPR22, GPR37, GPR85, GRB10, GRM3, GRM8, GSAP, GSDME, GTF2I, GTF2IRD1, GTF2IRD2, GTF2IRD2B, GTPBP10, GUSB, H2AZ2, HBP1, HDAC9, HECW1, HECW1-IT1, HEPACAM2, HERPUD2, HGF, HIBADH, HILPDA, HIP1, HNRNPA2B1, HOTAIRM1, HOTTIP, HOXA1, HOXA10, HOXA11, HOXA13, HOXA2, HOXA3, HOXA4, HOXA5, HOXA6, HOXA7, HOXA9, HSPB1, HUS1, HYAL4, HYCC1, IFRD1, IFT22, IFT56, IGF2BP3, IGFBP1, IGFBP3, IKZF1, IL6, IMMP2L, IMPDH1, ING3, INHBA, INMT, IQUB, IRF5, ITGB8, ITPRID1, JAZF1, KBTBD2, KCND2, KCP, KCTD7, KDM7A, KIAA1549, KLF14, KLHDC10, KLHL7, KLHL7-DT, KLRG2, KMT2E, KPNA7, KRIT1, LAMB1, LAMB4, LAMTOR4, LANCL2, LAT2, LEP, LHFPL3, LIMK1, LINC02860, LINC02902, LINC02903, LMOD2, LMTK2, LOC101928861, LRCH4, LRGUK, LRRC17, LRRC4, LRRC72, LRRD1, LRRN3, LRWD1, LSM5, LSM8, LSMEM1, LUC7L2, LUZP6, MACC1, MAGI2, MALSU1, MATCAP2, MBLAC1, MCM7, MDFIC, MDH2, MEOX2, MEPCE, MEST, MESTIT1, MET, METTL27, METTL2B, MINDY4, MIR106B, MIR148A, MIR182, MIR183, MIR196B, MIR25, MIR29A, MIR29B1, MIR335, MIR489, MIR590, MIR93, MIR96, MKLN1, MKRN1, MLXIPL, MOGAT3, MOSPD3, MPLKIP, MRPL32, MRPS17, MRPS24, MTERF1, MTPN, MTURN, MUC12, MUC17, MUC3A, MYL10, MYL7, MYO1G, NACAD, NAMPT, NAPEPLD, NAT16, NCF1, NDUFA5, NDUFB2, NEUROD6, NFE2L3, NFE4, NIPSNAP2, NME8, NOD1, NPC1L1, NPSR1, NPTX2, NPVF, NPY, NRCAM, NRF1, NSUN5, NT5C3A, NUDCD3, NUP205, NUP42, NUPR2, NYAP1, OCM2, OGDH, OPN1SW, OR2AE1, ORAI2, ORC5, OSBPL3, PALS2, PARP12, PAX4, PCLO, PCOLCE, PDAP1, PDE1C, PDK4, PEG10, PEX1, PGAM2, PHKG1, PHTF2, PIK3CG, PILRA, PKD1L1, PLEKHA8, PLOD3, PLXNA4, PMPCB, PNPLA8, PODXL, POLD2, POLM, POLR1F, POLR2J, POLR2J2, POLR2J3, POM121, POM121C, POM121L12, POMZP3, PON1, PON2, PON3, POP7, POR, POT1, POU6F2, PPIA, PPP1R17, PPP1R35, PPP1R3A, PPP1R9A, PRKAR2B, PRKRIP1, PRPS1L1, PRR15, PRRT4, PSMA2, PSMC2, PSPH, PTCD1, PTN, PTPN12, PTPRZ1, PURB, PUS7, PVRIG, RAB19, RABGEF1, RALA, RAMP3, RAPGEF5, RASA4, RASA4B, RBM28, RBM48, RCC1L, RELN, RFC2, RHBDD2, RINT1, RNF133, RNF148, RNU2-1, RP9, RSBN1L, RUNDC3B, SAMD9, SAMD9L, SAP25, SBDS, SCIN, SCRN1, SDHAF3, SEC61G, SEM1, SEMA3A, SEMA3C, SEMA3D, SEMA3E, SEPTIN14, SEPTIN7, SERPINE1, SFRP4, SGCE, SH2B2, SKAP2, SLC12A9, SLC13A1, SLC13A4, SLC25A13, SLC25A40, SLC26A3, SLC26A4, SLC26A5, SLC35B4, SLC37A3, SMKR1, SMO, SMURF1, SND1, SNHG15, SNORA5C, SNX10, SNX13, SOSTDC1, SP4, SP8, SPACDR, SPAM1, SPATA48, SPDYE1, SPDYE2, SPDYE2B, SPDYE3, SPDYE5, SPDYE6, SRI, SRPK2, SRRM3, SRRT, SSC4D, SSMEM1, ST7, ST7-OT3, ST7-OT4, STAG3, STARD3NL, STEAP1, STEAP1B, STEAP2, STEAP4, STK17A, STK31, STMP1, STRA8, STRIP2, STX1A, STYXL1, SUGCT, SUMF2, SUN3, SVOPL, SYPL1, TAC1, TAF6, TARP, TAS2R16, TAX1BP1, TBL2, TBRG4, TBX20, TBXAS1, TECPR1, TES, TEX47, TFEC, TFPI2, TFR2, THAP5, TMED4, TMEM106B, TMEM120A, TMEM130, TMEM140, TMEM168, TMEM196, TMEM209, TMEM213, TMEM229A, TMEM243, TMEM248, TMEM270, TMEM60, TNPO3, TNS3, TOMM7, TPST1, TRA2A, TRAPPC14, TRIL, TRIM24, TRIM4, TRIM50, TRIM56, TRIM73, TRIM74, TRIP6, TRRAP, TSC22D4, TSGA13, TSPAN12, TSPAN13, TSPAN33, TWIST1, TYW1, TYW1B, UBE2D4, UBE2H, UBN2, UFSP1, UPK3BL1, UPP1, URGCP, VGF, VKORC1L1, VOPP1, VPS37D, VPS41, VPS50, VSTM2A, VWC2, VWDE, WASL, WDR91, WIPF3, WNT16, WNT2, YAE1, YKT6, YWHAG, ZAN, ZASP, ZC3HAV1, ZC3HAV1L, ZC3HC1, ZCWPW1, ZKSCAN1, ZKSCAN5, ZMIZ2, ZNF107, ZNF117, ZNF138, ZNF273, ZNF277, ZNF3, ZNF394, ZNF479, ZNF655, ZNF679, ZNF680, ZNF713, ZNF716, ZNF727, ZNF735, ZNF736, ZNF789, ZNF800, ZNF804B, ZNF92, ZNHIT1, ZNRF2, ZP3, ZPBP, ZSCAN21, ZSCAN25 1 0 0 1
CACNA1A 0 0 1 1
FLCN 0 1 0 1
KRAS 1 0 0 1
NF1 1 0 0 1
PALB2 0 0 1 1
RET 0 0 1 1
SDHA 1 0 0 1
TP53 1 0 0 1

Submitter and significance breakdown #

Total submitters: 5
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Submitter pathogenic likely pathogenic uncertain significance total
St. Jude Molecular Pathology, St. Jude Children's Research Hospital 3 1 2 6
Yale Center for Mendelian Genomics, Yale University 0 0 2 2
OMIM 1 0 0 1
Clinical Molecular Genetics Laboratory, Johns Hopkins All Children's Hospital 0 0 1 1
Columbia University Laboratory of Personalized Genomic Medicine, Columbia University Medical Center 1 0 0 1

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