ClinVar Miner

Variants studied for adrenal carcinoma

Included ClinVar conditions (8):
Minimum submission review status: Collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than one submission, it may be counted in more than one significance column. If this is the case, the total number of variants will be less than the sum of the other cells.

pathogenic likely pathogenic uncertain significance likely benign benign not provided total
59 86 129 47 10 2 309

Gene and significance breakdown #

Total genes and gene combinations: 11
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Gene or gene combination pathogenic likely pathogenic uncertain significance likely benign benign not provided total
RET 54 19 123 46 10 2 231
TP53 5 40 4 0 0 0 48
CTNNB1 0 11 0 0 0 0 11
NRAS 0 5 0 0 0 0 5
PIK3CA 0 4 0 0 0 0 4
BRAF 0 3 0 0 0 0 3
GNAS 0 3 0 0 0 0 3
CHEK2 0 0 1 0 0 0 1
H3F3A 0 1 0 0 0 0 1
LOC106736614, RET 0 0 1 0 0 0 1
LOC110121502, MCS+9.7, RET 0 0 0 1 0 0 1

Submitter and significance breakdown #

Total submitters: 19
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Submitter pathogenic likely pathogenic uncertain significance likely benign benign not provided total
Counsyl 7 2 84 45 6 0 144
Database of Curated Mutations (DoCM) 0 79 0 0 0 0 79
Mendelics 1 0 43 2 2 0 48
ARUP Institute,ARUP Laboratories 31 0 0 0 0 0 31
Fulgent Genetics 7 2 19 0 0 0 28
OMIM 20 0 0 0 0 0 20
EGL Genetic Diagnostics,Eurofins Clinical Diagnostics 7 0 0 0 0 0 7
Center for Human Genetics, Inc 3 0 2 0 0 0 5
Integrated Genetics/Laboratory Corporation of America 2 0 2 0 1 0 5
Clinical Molecular Genetics Laboratory,Johns Hopkins All Children's Hospital 4 0 0 0 0 0 4
Human Genome Sequencing Center Clinical Lab,Baylor College of Medicine 3 1 0 0 0 0 4
Equipe Genetique des Anomalies du Developpement,Université de Bourgogne 0 0 3 0 1 0 4
ClinVar Staff, National Center for Biotechnology Information (NCBI) 0 0 0 0 0 1 1
CSER_CC_NCGL; University of Washington Medical Center 0 0 1 0 0 0 1
Foundation for Research in Genetics and Endocrinology,Institute of Human Genetics 0 1 0 0 0 0 1
Donald Williams Parsons Laboratory,Baylor College of Medicine 0 1 0 0 0 0 1
Centre for Mendelian Genomics,University Medical Centre Ljubljana 0 0 1 0 0 0 1
GenomeConnect, ClinGen 0 0 0 0 0 1 1
Department of Genetics,Sultan Qaboos University Hospital, Oman 0 0 1 0 0 0 1

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