ClinVar Miner

Variants studied for psoriasis

Included ClinVar conditions (7):
Minimum submission review status: Collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than one submission, it may be counted in more than one significance column. If this is the case, the total number of variants will be less than the sum of the other cells.

pathogenic likely pathogenic uncertain significance likely benign benign risk factor not provided total
19 12 670 425 116 2 2 1216

Gene and significance breakdown #

Total genes and gene combinations: 11
Download table as spreadsheet
Gene or gene combination pathogenic likely pathogenic uncertain significance likely benign benign risk factor not provided total
CARD14 6 3 354 230 49 0 0 639
CARD14, SGSH 0 0 156 97 32 0 0 283
IL36RN 12 7 100 59 23 0 2 179
CARD14, LOC126862662, SGSH 0 0 57 37 10 0 0 104
AP1S3 0 0 0 2 1 2 0 4
CARD14, CCDC40, EIF4A3, GAA 0 0 2 0 0 0 0 2
C1QTNF1, CANT1, CARD14, CBX2, CBX4, CBX8, CCDC40, EIF4A3, ENGASE, ENPP7, GAA, LGALS3BP, RBFOX3, RNF213, SGSH, SLC26A11, TBC1D16, TIMP2 0 0 1 0 0 0 0 1
IL17RA 0 1 0 0 0 0 0 1
IL1F10, IL1RN, IL36RN 1 0 0 0 0 0 0 1
IL1F10, IL36RN 0 1 0 0 0 0 0 1
LPIN2 0 0 0 0 1 0 0 1

Submitter and significance breakdown #

Total submitters: 29
Download table as spreadsheet
Submitter pathogenic likely pathogenic uncertain significance likely benign benign risk factor not provided total
Labcorp Genetics (formerly Invitae), Labcorp 9 7 622 413 88 0 0 1139
Illumina Laboratory Services, Illumina 1 1 39 5 21 0 0 67
OMIM 12 0 0 0 0 2 0 14
Fulgent Genetics, Fulgent Genetics 0 0 7 6 1 0 0 14
Genome-Nilou Lab 0 0 0 0 12 0 0 12
Clinical Genomics, Uppaluri K&H Personalized Medicine Clinic 0 0 6 0 0 0 0 6
Center for Genomics, Ann and Robert H. Lurie Children's Hospital of Chicago 0 0 3 1 0 0 0 4
Al Jalila Children’s Genomics Center, Al Jalila Childrens Speciality Hospital 0 0 0 1 1 0 0 2
Baylor Genetics 1 0 0 0 0 0 0 1
Laboratory for Molecular Medicine, Mass General Brigham Personalized Medicine 0 1 0 0 0 0 0 1
Revvity Omics, Revvity 1 0 0 0 0 0 0 1
MGZ Medical Genetics Center 0 0 1 0 0 0 0 1
Mendelics 1 0 0 0 0 0 0 1
Victorian Clinical Genetics Services, Murdoch Childrens Research Institute 1 0 0 0 0 0 0 1
Center for Genomic Medicine, King Faisal Specialist Hospital and Research Center 0 0 1 0 0 0 0 1
Clinical Genomics Laboratory, Washington University in St. Louis 0 0 1 0 0 0 0 1
Nemer Genomics and Translation Biomedicine Lab, American University of Beirut 0 1 0 0 0 0 0 1
Soonchunhyang University Bucheon Hospital, Soonchunhyang University Medical Center 0 0 1 0 0 0 0 1
Genetics and Molecular Pathology, SA Pathology 0 0 1 0 0 0 0 1
GenomeConnect, ClinGen 0 0 0 0 0 0 1 1
Seattle Children's Hospital Molecular Genetics Laboratory, Seattle Children's Hospital 1 0 0 0 0 0 0 1
Broad Center for Mendelian Genomics, Broad Institute of MIT and Harvard 0 0 0 0 1 0 0 1
Reproductive Health Research and Development, BGI Genomics 1 0 0 0 0 0 0 1
Zotz-Klimas Genetics Lab, MVZ Zotz Klimas 0 1 0 0 0 0 0 1
New York Genome Center 0 0 1 0 0 0 0 1
Beijing Key Laboratry for Genetics of Birth Defects, Beijing Children's Hospital 0 1 0 0 0 0 0 1
GenomeConnect - Invitae Patient Insights Network 0 0 0 0 0 0 1 1
Department of Human Genetics, Hannover Medical School 0 1 0 0 0 0 0 1
Medical Laboratory Center, Huzhou Maternal and Child Health Hospital 1 0 0 0 0 0 0 1

The information on this website is not intended for direct diagnostic use or medical decision-making without review by a genetics professional. Individuals should not change their health behavior solely on the basis of information contained on this website. Neither the University of Utah nor the National Institutes of Health independently verfies the submitted information. If you have questions about the information contained on this website, please see a health care professional.