Variants studied for mood disorder

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

If a variant has more than one submission, it may be counted in more than one significance column. If this is the case, the total number of variants will be less than the sum of the other cells.

pathogenic	likely pathogenic	uncertain significance	likely benign	benign	affects	drug response	risk factor	not provided	total
2	2	8	1	0	1	1	1	2	18

Gene and significance breakdown #

Total genes and gene combinations: 10

Download table as spreadsheet

Gene or gene combination	pathogenic	likely pathogenic	uncertain significance	likely benign	affects	drug response	risk factor	not provided	total
TPH2	0	0	2	1	0	0	1	0	4
intergenic	1	0	2	0	0	0	0	0	3
APOE	0	0	0	0	0	0	0	2	2
MRE11	0	0	2	0	0	0	0	0	2
NOTCH3	1	1	0	0	0	0	0	0	2
CLCN2	0	0	1	0	0	0	0	0	1
HTR2A	0	0	0	0	0	1	0	0	1
OGDHL	0	0	0	0	1	0	0	0	1
TWNK	0	1	0	0	0	0	0	0	1
XBP1	0	0	1	0	0	0	0	0	1

Submitter and significance breakdown #

Total submitters: 8

Download table as spreadsheet

Submitter	pathogenic	likely pathogenic	uncertain significance	likely benign	affects	drug response	risk factor	not provided	total
Centre for Mendelian Genomics, University Medical Centre Ljubljana	0	1	3	0	0	0	0	0	4
Fulgent Genetics, Fulgent Genetics	0	0	2	1	0	0	0	0	3
Talkowski Laboratory, Center for Human Genetic Research, Massachusetts General Hospital	1	0	2	0	0	0	0	0	3
OMIM	0	0	0	0	0	1	1	0	2
Alzheimer Center and Department of Neurology, VU University Medical Center	0	0	0	0	0	0	0	2	2
NIHR Bioresource Rare Diseases, University of Cambridge	1	1	0	0	0	0	0	0	2
ARUP Laboratories, Molecular Genetics and Genomics, ARUP Laboratories	0	0	1	0	0	0	0	0	1
Key Laboratory of Real Time Tracing of Brain Circuits of Neurology and Psychiatry, Nankai University Affiliated Tianjin Fourth Center Hospital	0	0	0	0	1	0	0	0	1

The information on this website is not intended for direct diagnostic use or medical decision-making without review by a genetics professional. Individuals should not change their health behavior solely on the basis of information contained on this website. Neither the University of Utah nor the National Institutes of Health independently verfies the submitted information. If you have questions about the information contained on this website, please see a health care professional.