ClinVar Miner

Variants studied for childhood malignant neoplasm

Included ClinVar conditions (6):
Minimum submission review status: Collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than one submission, it may be counted in more than one significance column. If this is the case, the total number of variants will be less than the sum of the other cells.

pathogenic likely pathogenic uncertain significance likely benign benign other not provided total
15 9 28 22 20 1 1 95

Gene and significance breakdown #

Total genes and gene combinations: 9
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Gene or gene combination pathogenic likely pathogenic uncertain significance likely benign benign other not provided total
DICER1 9 7 27 22 20 0 1 85
MET 3 0 0 0 0 0 0 3
BCAN, BGLAP, CCT3, CRABP2, GLMP, GPATCH4, HAPLN2, HDGF, INSRR, IQGAP3, ISG20L2, LMNA, MEF2D, METTL25B, MIR9-1, MIR9-1HG, MRPL24, NAXE, NES, NTRK1, PAQR6, PMF1, PMF1-BGLAP, PRCC, RHBG, SEMA4A, SH2D2A, SLC25A44, SMG5, TMEM79, TSACC, TTC24, VHLL 1 0 0 0 0 0 0 1
BRCA2 1 0 0 0 0 0 0 1
BRIP1 0 1 0 0 0 0 0 1
MET, RBPMS 0 0 0 0 0 1 0 1
NF1 0 0 1 0 0 0 0 1
SUFU 0 1 0 0 0 0 0 1
TP53 1 0 0 0 0 0 0 1

Submitter and significance breakdown #

Total submitters: 13
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Submitter pathogenic likely pathogenic uncertain significance likely benign benign other not provided total
KCCC/NGS Laboratory, Kuwait Cancer Control Center 0 0 0 8 16 0 0 24
St. Jude Molecular Pathology, St. Jude Children's Research Hospital 4 2 15 0 0 0 0 21
Illumina Laboratory Services, Illumina 0 0 7 6 4 0 0 17
Fulgent Genetics, Fulgent Genetics 1 0 4 9 1 0 0 15
OMIM 9 0 0 0 0 0 0 9
MGZ Medical Genetics Center 0 1 2 0 0 0 0 3
Center for Genomic Medicine, King Faisal Specialist Hospital and Research Center 1 2 0 0 0 0 0 3
Foulkes Cancer Genetics LDI, Lady Davis Institute for Medical Research 0 2 0 0 0 0 0 2
Institute for Genomic Medicine (IGM) Clinical Laboratory, Nationwide Children's Hospital 0 0 0 0 0 1 0 1
Center for Genomics, Ann and Robert H. Lurie Children's Hospital of Chicago 0 1 0 0 0 0 0 1
Michigan Center for Translational Pathology, University of Michigan 1 0 0 0 0 0 0 1
GenomeConnect - Invitae Patient Insights Network 0 0 0 0 0 0 1 1
Medizinische Genetik Mainz, Limbach Genetics GmbH 0 1 0 0 0 0 0 1

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