If a variant has more than one submission, it may be counted in more than one significance column. If this is the
case, the total number of variants will be less than the sum of the other cells.
pathogenic |
likely pathogenic |
uncertain significance |
likely benign |
benign |
association |
not provided |
total |
6
|
6
|
580
|
364
|
92
|
2
|
1
|
1034
|
Gene and significance breakdown #
Total genes and gene combinations: 7
Gene or gene combination |
pathogenic |
likely pathogenic |
uncertain significance |
likely benign |
benign |
association |
not provided |
total |
CARD14
|
4
|
3
|
359
|
230
|
50
|
1
|
1
|
638
|
CARD14, SGSH
|
0 |
0 |
159
|
97
|
32
|
0 |
0 |
283
|
CARD14, LOC126862662, SGSH
|
0 |
1
|
57
|
37
|
10
|
1
|
0 |
104
|
SYK
|
2
|
2
|
1
|
0 |
0 |
0 |
0 |
5
|
CARD14, CCDC40, EIF4A3, GAA
|
0 |
0 |
2
|
0 |
0 |
0 |
0 |
2
|
intergenic
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
C1QTNF1, CANT1, CARD14, CBX2, CBX4, CBX8, CCDC40, EIF4A3, ENGASE, ENPP7, GAA, LGALS3BP, RBFOX3, RNF213, SGSH, SLC26A11, TBC1D16, TIMP2
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
Submitter and significance breakdown #
Submitter |
pathogenic |
likely pathogenic |
uncertain significance |
likely benign |
benign |
association |
not provided |
total |
Labcorp Genetics (formerly Invitae), Labcorp
|
3
|
3
|
567
|
360
|
85
|
0 |
0 |
1018
|
Genome-Nilou Lab
|
0 |
0 |
0 |
0 |
12
|
0 |
0 |
12
|
Fulgent Genetics, Fulgent Genetics
|
0 |
0 |
4
|
4
|
1
|
0 |
0 |
9
|
Clinical Genomics, Uppaluri K&H Personalized Medicine Clinic
|
0 |
1
|
5
|
0 |
0 |
2
|
0 |
8
|
Aleixo Muise Laboratory, Hospital For Sick Children
|
2
|
2
|
1
|
0 |
0 |
0 |
0 |
5
|
Center for Genomics, Ann and Robert H. Lurie Children's Hospital of Chicago
|
0 |
0 |
3
|
1
|
0 |
0 |
0 |
4
|
OMIM
|
3
|
0 |
0 |
0 |
0 |
0 |
0 |
3
|
Mendelics
|
0 |
0 |
0 |
0 |
1
|
0 |
0 |
1
|
Victorian Clinical Genetics Services, Murdoch Childrens Research Institute
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
Clinical Genomics Laboratory, Washington University in St. Louis
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
Talkowski Laboratory, Center for Human Genetic Research, Massachusetts General Hospital
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
Centre for Mendelian Genomics, University Medical Centre Ljubljana
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
Institute of Human Genetics, University of Leipzig Medical Center
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
New York Genome Center
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
3billion
|
0 |
0 |
1
|
0 |
0 |
0 |
0 |
1
|
GenomeConnect - Invitae Patient Insights Network
|
0 |
0 |
0 |
0 |
0 |
0 |
1
|
1
|
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