ClinVar Miner

Variants studied for PALB2-related cancer predisposition

Included ClinVar conditions (8):
Minimum submission review status: Collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than one submission, it may be counted in more than one significance column. If this is the case, the total number of variants will be less than the sum of the other cells.

pathogenic likely pathogenic uncertain significance likely benign benign risk factor not provided total
39 15 153 38 2 4 2 249

Gene and significance breakdown #

Total genes and gene combinations: 2
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Gene or gene combination pathogenic likely pathogenic uncertain significance likely benign benign risk factor not provided total
PALB2 38 15 153 38 2 3 2 248
DCTN5, PALB2 1 0 0 0 0 1 0 1

Submitter and significance breakdown #

Total submitters: 17
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Submitter pathogenic likely pathogenic uncertain significance likely benign benign risk factor not provided total
Fulgent Genetics, Fulgent Genetics 27 5 136 37 2 0 0 207
Juno Genomics, Hangzhou Juno Genomics, Inc 7 4 0 0 0 0 0 11
Department of Pathology and Laboratory Medicine, Sinai Health System 3 1 5 1 0 0 0 10
Leiden Open Variation Database 2 0 8 0 0 0 0 10
Human Genome Sequencing Center Clinical Lab, Baylor College of Medicine 3 3 1 0 0 0 0 7
OMIM 0 0 0 0 0 4 0 4
MGZ Medical Genetics Center 0 1 1 0 0 0 0 2
GenomeConnect - Invitae Patient Insights Network 0 0 0 0 0 0 2 2
Clinical Genomics Laboratory, Washington University in St. Louis 1 0 0 0 0 0 0 1
Genetics and Molecular Pathology, SA Pathology 1 0 0 0 0 0 0 1
Institute of Human Genetics, University of Leipzig Medical Center 1 0 0 0 0 0 0 1
Center for Genomics, Ann and Robert H. Lurie Children's Hospital of Chicago 0 0 1 0 0 0 0 1
Institute of Human Genetics, Clinical Exome/Genome Diagnostics Group, University Hospital Bonn 1 0 0 0 0 0 0 1
Neuberg Centre For Genomic Medicine, NCGM 0 1 0 0 0 0 0 1
Clinical Genetics Laboratory, University Hospital Schleswig-Holstein 1 0 0 0 0 0 0 1
Laboratorio de Genetica e Diagnostico Molecular, Hospital Israelita Albert Einstein 0 0 1 0 0 0 0 1
Institute of Immunology and Genetics Kaiserslautern 0 0 1 0 0 0 0 1

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