ClinVar Miner

Variants studied for Wilms tumor 1

Included ClinVar conditions (11):
Minimum submission review status: Collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than one submission, it may be counted in more than one significance column. If this is the case, the total number of variants will be less than the sum of the other cells.

pathogenic likely pathogenic uncertain significance likely benign benign not provided total
168 28 1317 867 136 5 2468

Gene and significance breakdown #

Total genes and gene combinations: 11
Download table as spreadsheet
Gene or gene combination pathogenic likely pathogenic uncertain significance likely benign benign not provided total
GPC3 41 6 427 297 69 0 832
WT1 41 13 375 333 37 4 774
LOC107982234, WT1 18 4 436 211 12 0 665
BRCA2 65 4 70 26 17 1 183
TRIM28 0 0 6 0 0 0 6
LOC106707172, LOC107982234, LOC130005479, WT1 2 0 0 0 0 0 2
LOC130065239, TRIM28 0 0 2 0 0 0 2
DCDC1, DNAJC24, ELP4, IMMP1L, PAX6, RCN1, WT1 1 0 0 0 0 0 1
GPC4 0 0 0 0 1 0 1
IGF2, INS-IGF2 0 1 0 0 0 0 1
MED12 0 0 1 0 0 0 1

Submitter and significance breakdown #

Total submitters: 28
Download table as spreadsheet
Submitter pathogenic likely pathogenic uncertain significance likely benign benign not provided total
Invitae 92 15 1142 800 100 0 2149
Fulgent Genetics, Fulgent Genetics 71 5 117 55 18 0 266
All of Us Research Program, National Institutes of Health 0 2 139 84 4 0 229
Illumina Laboratory Services, Illumina 0 0 48 11 23 0 82
Genome-Nilou Lab 0 0 0 0 18 0 18
St. Jude Molecular Pathology, St. Jude Children's Research Hospital 3 0 14 0 0 0 17
Mendelics 0 0 12 0 1 0 13
KCCC/NGS Laboratory, Kuwait Cancer Control Center 0 0 0 3 10 0 13
Baylor Genetics 4 2 4 0 0 0 10
OMIM 9 0 0 0 0 0 9
Athena Diagnostics Inc 0 0 0 0 3 0 3
GeneReviews 0 0 0 0 0 3 3
Molecular Genetics and NGS Laboratory, Hospital Fundacion Valle Del Lili 2 1 0 0 0 0 3
Human Genome Sequencing Center Clinical Lab, Baylor College of Medicine 0 1 1 0 0 0 2
Centre for Mendelian Genomics, University Medical Centre Ljubljana 0 0 2 0 0 0 2
Genetics and Molecular Pathology, SA Pathology 1 1 0 0 0 0 2
Institute of Human Genetics, Clinical Exome/Genome Diagnostics Group, University Hospital Bonn 2 0 0 0 0 0 2
Genomic Diagnostic Laboratory, Division of Genomic Diagnostics, Children's Hospital of Philadelphia 0 0 0 1 0 0 1
Institute of Human Genetics, Cologne University 1 0 0 0 0 0 1
Women's Health and Genetics/Laboratory Corporation of America, LabCorp 1 0 0 0 0 0 1
Institute for Human Genetics and Genomic Medicine, Uniklinik RWTH Aachen 0 1 0 0 0 0 1
Donald Williams Parsons Laboratory, Baylor College of Medicine 1 0 0 0 0 0 1
GenomeConnect, ClinGen 0 0 0 0 0 1 1
Center for Genomics, Ann and Robert H. Lurie Children's Hospital of Chicago 0 0 1 0 0 0 1
Génétique des Maladies du Développement, Hospices Civils de Lyon 0 0 1 0 0 0 1
Johns Hopkins Genomics, Johns Hopkins University 1 0 0 0 0 0 1
GenomeConnect - Invitae Patient Insights Network 0 0 0 0 0 1 1
Laan Lab, Human Genetics Research Group, University of Tartu 0 1 0 0 0 0 1

The information on this website is not intended for direct diagnostic use or medical decision-making without review by a genetics professional. Individuals should not change their health behavior solely on the basis of information contained on this website. Neither the University of Utah nor the National Institutes of Health independently verfies the submitted information. If you have questions about the information contained on this website, please see a health care professional.