ClinVar Miner

Variants from Liquid Biopsy and Cancer Interception Group, Pfizer-University of Granada-Junta de Andalucía Centre for Genomics and Oncological Research

Location: Spain  Primary collection method: research
Minimum submission review status: Collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than one submission, it may be counted in more than one significance column. If this is the case, the total number of variants will be less than the sum of the other cells.

pathogenic likely pathogenic uncertain significance likely benign benign risk factor total
23 1 127 6 8 1 165

Gene and significance breakdown #

Total genes and gene combinations: 59
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Gene or gene combination pathogenic likely pathogenic uncertain significance likely benign benign risk factor total
MUC5AC 0 0 10 1 0 0 11
TP53 6 1 4 0 0 0 11
NLRP3 0 0 9 0 0 0 9
EGFR 2 0 5 0 0 0 7
FLT1 0 0 6 0 1 0 7
ROS1 1 0 4 0 1 0 6
ADAM19 0 0 5 0 0 0 5
ADAMTSL3 0 0 5 0 0 0 5
BRCA1 1 0 4 0 0 0 5
MLH1 0 0 5 0 0 0 5
RIN3 0 0 5 0 0 0 5
ATM, C11orf65 2 0 2 0 0 0 4
BRCA2 2 0 2 0 0 0 4
FOXP2 0 0 4 0 0 0 4
RB1 2 0 1 0 1 0 4
TLR4 0 0 2 2 0 0 4
ADGRG6 0 0 3 0 0 0 3
AKT1 0 0 2 0 1 0 3
CD163 0 0 3 0 0 0 3
DDR2 0 0 2 0 1 0 3
FOXP4 0 0 3 0 0 0 3
HTR4 0 0 1 1 1 0 3
PTCH1 0 0 2 1 0 0 3
APC 0 0 2 0 0 0 2
ATM 2 0 0 0 0 0 2
CHEK2 1 0 1 0 0 0 2
CHRNA3 0 0 2 0 0 0 2
CHRNA3, CHRNA5 0 0 2 0 0 0 2
FAM13A 1 0 1 0 0 0 2
FGF10 1 0 1 0 0 0 2
IREB2 0 0 2 0 0 0 2
LOC110006318, STK11 0 0 2 0 0 0 2
NKX2-1, SFTA3 0 0 1 0 1 0 2
RAD50 0 0 2 0 0 0 2
RAD51C 1 0 0 0 0 1 2
ALK 0 0 1 0 0 0 1
ALX1 0 0 1 0 0 0 1
CHRNA5 0 0 1 0 0 0 1
CHRNB4 0 0 1 0 0 0 1
EGR1, LOC126807524 0 0 1 0 0 0 1
FLT1, LOC124849303 0 0 1 0 0 0 1
FLT1, LOC130009460 0 0 1 0 0 0 1
FOXP4, LOC129996415 0 0 1 0 0 0 1
FOXP4, LOC129996416 0 0 1 0 0 0 1
FPR2 0 0 1 0 0 0 1
LOC126860749, TLR4 0 0 1 0 0 0 1
LOC126861112, MUC5AC 0 0 1 0 0 0 1
LOC130002133, PTCH1 0 0 1 0 0 0 1
MSH2 0 0 1 0 0 0 1
MSH6 0 0 1 0 0 0 1
NBN 0 0 1 0 0 0 1
PALB2 1 0 0 0 0 0 1
PITX2 0 0 1 0 0 0 1
PTEN 0 0 1 1 0 0 1
SERPINA1 0 0 1 0 0 0 1
SLC22A18 0 0 1 0 0 0 1
STK11 0 0 0 0 1 0 1
TET2 0 0 1 0 0 0 1
TGFB2 0 0 1 0 0 0 1

Condition and significance breakdown #

Total conditions: 5
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Condition pathogenic likely pathogenic uncertain significance likely benign benign risk factor total
Lung adenocarcinoma 9 1 83 4 4 0 101
Squamous cell carcinoma 4 0 29 2 4 0 39
Familial cancer of breast 6 0 7 0 0 0 13
Breast-ovarian cancer, familial, susceptibility to, 2 2 0 5 0 0 0 7
Breast-ovarian cancer, familial, susceptibility to, 1 2 0 3 0 0 1 6

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