Variants from ClinGen Monogenic Diabetes Variant Curation Expert Panel

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

If a variant has more than one submission, it may be counted in more than one significance column. If this is the case, the total number of variants will be less than the sum of the other cells.

pathogenic	likely pathogenic	uncertain significance	likely benign	benign	total
250	236	234	22	18	760

Gene and significance breakdown #

Total genes and gene combinations: 4

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Gene or gene combination	pathogenic	likely pathogenic	uncertain significance	likely benign	benign	total
HNF1A	87	82	128	8	9	314
GCK	129	118	50	6	3	306
HNF4A	32	32	44	8	3	119
C12orf43, HNF1A	2	4	13	0	3	22

Condition and significance breakdown #

Total conditions: 2

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Condition	pathogenic	likely pathogenic	uncertain significance	likely benign	benign	total
Monogenic diabetes	245	229	234	22	18	748
Maturity-onset diabetes of the young type 2	5	7	0	0	0	12

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