ClinVar Miner

Variants in gene ADGRG1 with conflicting interpretations

Y axis minimum submission review status: Y axis collection method:
X axis minimum submission review status: X axis collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than two submissions, it may have multiple conflicts and therefore be counted in more than one conflict column. If this is the case, the "Variants with any kind of conflict" cell will be less than the sum of the conflicted variants cells to its left.

Variants with only 1 submission per condition Variants with at least 2 submissions on the same condition and no conflicts Variants with a synonymous conflict
(e.g. benign vs non-pathogenic)
Variants with a confidence conflict
(e.g. benign vs likely benign)
Variants with a benign or likely benign vs uncertain conflict Variants with a category conflict
(e.g. benign vs affects)
Variants with a clinically significant conflict
(e.g. benign vs pathogenic)
Variants with any conflict
835 47 0 28 26 0 2 53

Significance breakdown #

In the table below, cells that correspond to a term paired with itself represent synonymous conflicts, i.e. variants that have been annotated with different terms that map to the same standard term. To compare the terms that were actually submitted, check the box in the filters section at the top of this page.

pathogenic likely pathogenic uncertain significance likely benign benign
pathogenic 0 7 1 0 0
likely pathogenic 7 0 1 0 0
uncertain significance 1 1 0 23 5
likely benign 0 0 23 0 21
benign 0 0 5 21 0

All variants with conflicting interpretations #

Total variants: 53
Download table as spreadsheet
HGVS dbSNP gnomAD frequency
NM_201525.4(ADGRG1):c.996T>C (p.Thr332=) rs1376041 0.79529
NM_201525.4(ADGRG1):c.1168-20C>A rs2305309 0.37206
NM_201525.4(ADGRG1):c.1286+6G>A rs74326170 0.05376
NM_201525.4(ADGRG1):c.1460T>C (p.Met487Thr) rs17379472 0.02860
NM_201525.4(ADGRG1):c.1933+10A>G rs137936275 0.00438
NM_201525.4(ADGRG1):c.844G>C (p.Gly282Arg) rs146704802 0.00404
NM_201525.4(ADGRG1):c.174C>T (p.Ile58=) rs140963173 0.00217
NM_201525.4(ADGRG1):c.1017+8G>A rs186479054 0.00196
NM_201525.4(ADGRG1):c.1287-28G>C rs60624815 0.00163
NM_201525.4(ADGRG1):c.1810C>T (p.Leu604=) rs113358058 0.00157
NM_201525.4(ADGRG1):c.1983T>C (p.Gly661=) rs111939130 0.00113
NM_201525.4(ADGRG1):c.243C>T (p.Phe81=) rs58068378 0.00094
NM_005682.7(ADGRG1):c.1952-19G>A rs200654268 0.00085
NM_201525.4(ADGRG1):c.612C>T (p.Pro204=) rs147495708 0.00053
NM_201525.4(ADGRG1):c.1356G>A (p.Thr452=) rs151020094 0.00035
NM_201525.4(ADGRG1):c.14C>T (p.Ser5Leu) rs147879224 0.00033
NM_201525.4(ADGRG1):c.214C>T (p.Pro72Ser) rs144561715 0.00030
NM_201525.4(ADGRG1):c.97C>T (p.Arg33Cys) rs776480483 0.00029
NM_201525.4(ADGRG1):c.401C>T (p.Pro134Leu) rs138344683 0.00018
NM_201525.4(ADGRG1):c.1188C>T (p.Asp396=) rs368883473 0.00014
NM_201525.4(ADGRG1):c.1287-6G>A rs112805221 0.00014
NM_201525.4(ADGRG1):c.1647C>T (p.Gly549=) rs2278808 0.00014
NM_201525.4(ADGRG1):c.760C>T (p.Arg254Trp) rs368130981 0.00014
NM_201525.4(ADGRG1):c.487A>C (p.Ser163Arg) rs373741981 0.00012
NM_201525.4(ADGRG1):c.1371C>T (p.Ser457=) rs747812668 0.00010
NM_201525.4(ADGRG1):c.26C>T (p.Thr9Met) rs200241873 0.00010
NM_201525.4(ADGRG1):c.1842C>T (p.Gly614=) rs574553979 0.00008
NM_201525.4(ADGRG1):c.1744A>T (p.Met582Leu) rs775708467 0.00006
NM_201525.4(ADGRG1):c.27G>A (p.Thr9=) rs142223451 0.00006
NM_201525.4(ADGRG1):c.1781G>A (p.Arg594His) rs757051705 0.00004
NM_201525.4(ADGRG1):c.1675C>T (p.Arg559Trp) rs121908464 0.00003
NM_201525.4(ADGRG1):c.1191C>T (p.Ala397=) rs1367685651 0.00001
NM_201525.4(ADGRG1):c.1236C>T (p.Val412=) rs768769972 0.00001
NM_201525.4(ADGRG1):c.1490T>C (p.Leu497Pro) rs587783654 0.00001
NM_201525.4(ADGRG1):c.1537C>T (p.Leu513=) rs762771228 0.00001
NM_201525.4(ADGRG1):c.1578G>A (p.Thr526=) rs727503955 0.00001
NM_201525.4(ADGRG1):c.286C>T (p.Arg96Ter) rs146278035 0.00001
NM_201525.4(ADGRG1):c.367C>T (p.Gln123Ter) rs1047016803 0.00001
NM_201525.4(ADGRG1):c.621-5G>A rs202245406 0.00001
NM_201525.4(ADGRG1):c.64+15G>T rs200303272 0.00001
NM_201525.4(ADGRG1):c.66T>G (p.Gly22=) rs369887735 0.00001
NM_201525.4(ADGRG1):c.733G>A (p.Gly245Ser) rs564786398 0.00001
NM_201525.4(ADGRG1):c.1010dup (p.Gln338fs)
NM_201525.4(ADGRG1):c.112C>T (p.Arg38Trp) rs121908462
NM_201525.4(ADGRG1):c.1442T>C (p.Leu481Pro) rs587783653
NM_201525.4(ADGRG1):c.1665-41C>T rs17240890
NM_201525.4(ADGRG1):c.1952G>A (p.Trp651Ter) rs587783657
NM_201525.4(ADGRG1):c.2040C>G (p.Gly680=) rs794727146
NM_201525.4(ADGRG1):c.272G>C (p.Cys91Ser) rs121908465
NM_201525.4(ADGRG1):c.412A>C (p.Thr138Pro) rs560954695
NM_201525.4(ADGRG1):c.641C>T (p.Ser214Leu) rs114515505
NM_201525.4(ADGRG1):c.843C>G (p.Ser281Arg) rs1801257
NM_201525.4(ADGRG1):c.843_844delinsGC (p.Ser281_Gly282delinsArgArg) rs1057517931

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