ClinVar Miner

Variants in gene BRIP1 with conflicting interpretations

See also:
Y axis minimum submission review status: Y axis collection method:
X axis minimum submission review status: X axis collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than two submissions, it may have multiple conflicts and therefore be counted in more than one conflict column. If this is the case, the "Variants with any kind of conflict" cell will be less than the sum of the conflicted variants cells to its left.

Variants with only 1 submission Variants with at least 2 submissions and no conflicts Variants with a synonymous conflict
(e.g. benign vs non-pathogenic)
Variants with a confidence conflict
(e.g. benign vs likely benign)
Variants with a benign or likely benign vs uncertain conflict Variants with a category conflict
(e.g. benign vs affects)
Variants with a clinically significant conflict
(e.g. benign vs pathogenic)
Variants with any kind of conflict
1128 713 0 90 90 0 19 183

Significance breakdown #

In the table below, cells that correspond to a term paired with itself represent synonymous conflicts, i.e. variants that have been annotated with different terms that map to the same standard term. To compare the terms that were actually submitted, check the box in the filters section at the top of this page.

pathogenic likely pathogenic uncertain significance likely benign benign
pathogenic 0 39 3 1 0
likely pathogenic 39 0 17 0 0
uncertain significance 3 17 0 89 15
likely benign 1 0 89 0 51
benign 0 0 15 51 0

All variants with conflicting interpretations #

Total variants: 183
Download table as spreadsheet
HGVS dbSNP
NM_032043.2(BRIP1):c.-30-3T>C rs370728413
NM_032043.2(BRIP1):c.-31+12G>A rs4988340
NM_032043.2(BRIP1):c.-5G>A rs754270436
NM_032043.2(BRIP1):c.-6A>C rs1442433909
NM_032043.2(BRIP1):c.1045G>C (p.Ala349Pro) rs149364097
NM_032043.2(BRIP1):c.1077A>G (p.Ile359Met) rs730881634
NM_032043.2(BRIP1):c.10A>G (p.Met4Val) rs45512093
NM_032043.2(BRIP1):c.1126_1127delCA (p.Gln376Asnfs) rs587780224
NM_032043.2(BRIP1):c.1141-4A>G rs1226658018
NM_032043.2(BRIP1):c.1141-94G>T rs114901675
NM_032043.2(BRIP1):c.1141-9A>G rs1555607258
NM_032043.2(BRIP1):c.1234_1235delGA (p.Glu412Serfs) rs1064795649
NM_032043.2(BRIP1):c.1240C>T (p.Gln414Ter) rs368796923
NM_032043.2(BRIP1):c.1257G>A (p.Arg419=) rs148429663
NM_032043.2(BRIP1):c.1340+9A>T rs376487588
NM_032043.2(BRIP1):c.1343G>A (p.Trp448Ter) rs775171520
NM_032043.2(BRIP1):c.1356C>T (p.Asn452=) rs730881640
NM_032043.2(BRIP1):c.1383T>C (p.Tyr461=) rs587780875
NM_032043.2(BRIP1):c.139C>A (p.Pro47Thr) rs28903098
NM_032043.2(BRIP1):c.139C>G (p.Pro47Ala) rs28903098
NM_032043.2(BRIP1):c.1425_1429delAACTT (p.Leu475Phefs) rs768736851
NM_032043.2(BRIP1):c.1432C>T (p.His478Tyr) rs761452695
NM_032043.2(BRIP1):c.1433A>G (p.His478Arg) rs45501097
NM_032043.2(BRIP1):c.1455T>C (p.Ala485=) rs773489367
NM_032043.2(BRIP1):c.1474-3T>C rs552752779
NM_032043.2(BRIP1):c.1510dupA (p.Ile504Asnfs) rs775735278
NM_032043.2(BRIP1):c.1552G>A (p.Val518Ile) rs786201701
NM_032043.2(BRIP1):c.1619A>T (p.Gln540Leu) rs4988349
NM_032043.2(BRIP1):c.1626C>T (p.Ser542=) rs373709958
NM_032043.2(BRIP1):c.1629-11T>C rs375710640
NM_032043.2(BRIP1):c.1629-3T>C rs587780828
NM_032043.2(BRIP1):c.1659A>G (p.Gln553=) rs876660693
NM_032043.2(BRIP1):c.1702_1703delAA (p.Asn568Trpfs) rs1057519365
NM_032043.2(BRIP1):c.1735C>T (p.Arg579Cys) rs28997571
NM_032043.2(BRIP1):c.1741C>T (p.Arg581Ter) rs780020495
NM_032043.2(BRIP1):c.1795-12_1795-10delGTT rs1475317357
NM_032043.2(BRIP1):c.1853_1854insG (p.Pro619Thrfs) rs587781985
NM_032043.2(BRIP1):c.1890A>G (p.Thr630=) rs145796331
NM_032043.2(BRIP1):c.1935+11_1935+13delGTT rs730881641
NM_032043.2(BRIP1):c.1935+7T>C rs201024366
NM_032043.2(BRIP1):c.1936-4C>T rs587780552
NM_032043.2(BRIP1):c.1936-7A>G rs1427111542
NM_032043.2(BRIP1):c.193C>T (p.Gln65Ter) rs575595017
NM_032043.2(BRIP1):c.1941G>A (p.Trp647Ter) rs786202760
NM_032043.2(BRIP1):c.1941G>C (p.Trp647Cys) rs786202760
NM_032043.2(BRIP1):c.1953T>C (p.Ile651=) rs754400631
NM_032043.2(BRIP1):c.195A>G (p.Gln65=) rs141436143
NM_032043.2(BRIP1):c.1972C>A (p.Arg658=) rs786203170
NM_032043.2(BRIP1):c.1989C>A (p.Thr663=) rs376628979
NM_032043.2(BRIP1):c.1A>G (p.Met1Val) rs764585550
NM_032043.2(BRIP1):c.1_2delAT (p.Met1Valfs) rs876661246
NM_032043.2(BRIP1):c.2038_2039dupTT (p.Leu680Phefs) rs587778134
NM_032043.2(BRIP1):c.205+1delG rs1057517648
NM_032043.2(BRIP1):c.2053C>T (p.Gln685Ter) rs876659533
NM_032043.2(BRIP1):c.206-21T>C rs2048717
NM_032043.2(BRIP1):c.2061G>C (p.Val687=) rs112414873
NM_032043.2(BRIP1):c.2097+7G>A rs4988352
NM_032043.2(BRIP1):c.2097+8A>C rs730881642
NM_032043.2(BRIP1):c.2098-3T>C rs1057520463
NM_032043.2(BRIP1):c.2111T>A (p.Leu704Ter) rs1057517643
NM_032043.2(BRIP1):c.2114_2118delAAGAA (p.Lys705Thrfs) rs864622611
NM_032043.2(BRIP1):c.2205dup (p.Asp736Terfs) rs1555591385
NM_032043.2(BRIP1):c.2220G>T (p.Gln740His) rs45589637
NM_032043.2(BRIP1):c.2223G>T (p.Val741=) rs1057522996
NM_032043.2(BRIP1):c.2232C>T (p.Asp744=) rs374362388
NM_032043.2(BRIP1):c.2236A>G (p.Ile746Val) rs111536363
NM_032043.2(BRIP1):c.2244C>G (p.Tyr748Ter) rs1257401983
NM_032043.2(BRIP1):c.2257+17T>C rs730881639
NM_032043.2(BRIP1):c.2257+5C>T rs1057523068
NM_032043.2(BRIP1):c.2258-1G>A rs1064793887
NM_032043.2(BRIP1):c.226G>A (p.Val76Ile) rs769573395
NM_032043.2(BRIP1):c.2273dupT (p.Ala759Serfs) rs587780236
NM_032043.2(BRIP1):c.2286T>C (p.Arg762=) rs61754141
NM_032043.2(BRIP1):c.2310T>C (p.Asp770=) rs148752066
NM_032043.2(BRIP1):c.2322C>T (p.Asp774=) rs1057520434
NM_032043.2(BRIP1):c.2377C>T (p.Gln793Ter) rs587782574
NM_032043.2(BRIP1):c.2392C>T (p.Arg798Ter) rs137852986
NM_032043.2(BRIP1):c.2400C>T (p.Tyr800=) rs574552037
NM_032043.2(BRIP1):c.2440C>T (p.Arg814Cys) rs201869624
NM_032043.2(BRIP1):c.2469G>T (p.Arg823Ser) rs587780239
NM_032043.2(BRIP1):c.2472C>T (p.Ala824=) rs767666616
NM_032043.2(BRIP1):c.2493-1G>A rs786203451
NM_032043.2(BRIP1):c.249A>G (p.Gln83=) rs45528833
NM_032043.2(BRIP1):c.2590G>A (p.Val864Ile) rs149529390
NM_032043.2(BRIP1):c.2637A>G (p.Glu879=) rs4986765
NM_032043.2(BRIP1):c.2686A>G (p.Ile896Val) rs764406913
NM_032043.2(BRIP1):c.2706A>G (p.Ile902Met) rs587780244
NM_032043.2(BRIP1):c.2751T>C (p.Ser917=) rs150780318
NM_032043.2(BRIP1):c.2755T>C (p.Ser919Pro) rs4986764
NM_032043.2(BRIP1):c.2765T>G (p.Leu922Ter) rs587782410
NM_032043.2(BRIP1):c.2801T>C (p.Phe934Ser) rs778916092
NM_032043.2(BRIP1):c.2804T>G (p.Val935Gly) rs4988356
NM_032043.2(BRIP1):c.2811T>C (p.Asp937=) rs374335608
NM_032043.2(BRIP1):c.2829C>A (p.Val943=) rs767164240
NM_032043.2(BRIP1):c.2854A>G (p.Ile952Val) rs200239986
NM_032043.2(BRIP1):c.2874A>T (p.Leu958=) rs886041147
NM_032043.2(BRIP1):c.2893A>C (p.Arg965=) rs113697814
NM_032043.2(BRIP1):c.2902A>G (p.Lys968Glu) rs587782679
NM_032043.2(BRIP1):c.2907T>C (p.Asn969=) rs1555572999
NM_032043.2(BRIP1):c.290_293delACAA (p.Asn97Metfs) rs763009188
NM_032043.2(BRIP1):c.2937A>G (p.Lys979=) rs75091137
NM_032043.2(BRIP1):c.2947delA (p.Ile983Leufs) rs774684620
NM_032043.2(BRIP1):c.297C>T (p.Asp99=) rs201617644
NM_032043.2(BRIP1):c.2990_2993delCAAA (p.Thr997Argfs) rs771028677
NM_032043.2(BRIP1):c.2990_2993dupCAAA (p.Lys998Asnfs) rs771028677
NM_032043.2(BRIP1):c.2992_2993delAA (p.Lys998Glufs) rs878855151
NM_032043.2(BRIP1):c.3009A>G (p.Ser1003=) rs751823379
NM_032043.2(BRIP1):c.3026G>A (p.Gly1009Glu) rs1555572908
NM_032043.2(BRIP1):c.3050C>T (p.Pro1017Leu) rs747907706
NM_032043.2(BRIP1):c.3064G>A (p.Glu1022Lys) rs587782808
NM_032043.2(BRIP1):c.3069C>T (p.Leu1023=) rs61754142
NM_032043.2(BRIP1):c.3070G>A (p.Gly1024Arg) rs147119272
NM_032043.2(BRIP1):c.3072delG (p.Ser1025Hisfs) rs1342519012
NM_032043.2(BRIP1):c.3079G>A (p.Glu1027Lys) rs371185409
NM_032043.2(BRIP1):c.3099T>C (p.Pro1033=) rs202228407
NM_032043.2(BRIP1):c.3103C>T (p.Arg1035Cys) rs45437094
NM_032043.2(BRIP1):c.312T>G (p.Thr104=) rs769190318
NM_032043.2(BRIP1):c.3149C>A (p.Thr1050Asn) rs373040333
NM_032043.2(BRIP1):c.316C>T (p.Arg106Cys) rs587780247
NM_032043.2(BRIP1):c.317G>A (p.Arg106His) rs143615668
NM_032043.2(BRIP1):c.3196delT (p.Ser1066Hisfs) rs730881645
NM_032043.2(BRIP1):c.3209C>A (p.Ser1070Ter) rs777213170
NM_032043.2(BRIP1):c.3230T>G (p.Leu1077Ter) rs1420431000
NM_032043.2(BRIP1):c.3240dupT (p.Ala1081Cysfs) rs779741278
NM_032043.2(BRIP1):c.3275C>T (p.Pro1092Leu) rs587780830
NM_032043.2(BRIP1):c.3328G>T (p.Glu1110Ter) rs1060501774
NM_032043.2(BRIP1):c.3378A>C (p.Glu1126Asp) rs145855459
NM_032043.2(BRIP1):c.3390_3393delCTAT (p.Tyr1131Leufs) rs778664039
NM_032043.2(BRIP1):c.3401delC (p.Pro1134Leufs) rs756853672
NM_032043.2(BRIP1):c.3411T>C (p.Tyr1137=) rs4986763
NM_032043.2(BRIP1):c.3440dup (p.Asn1147Lysfs) rs753683450
NM_032043.2(BRIP1):c.3444C>A (p.Asp1148Glu) rs28997573
NM_032043.2(BRIP1):c.3459T>C (p.Asp1153=) rs4987050
NM_032043.2(BRIP1):c.3525dupT (p.Ile1176Tyrfs) rs777367075
NM_032043.2(BRIP1):c.3571A>G (p.Ile1191Val) rs761405340
NM_032043.2(BRIP1):c.357T>C (p.Asn119=) rs786202477
NM_032043.2(BRIP1):c.36G>T (p.Gly12=) rs45566938
NM_032043.2(BRIP1):c.380-17T>A rs200050729
NM_032043.2(BRIP1):c.380-17delT rs545021924
NM_032043.2(BRIP1):c.380-17dupT rs545021924
NM_032043.2(BRIP1):c.380-5A>G rs587782131
NM_032043.2(BRIP1):c.387T>C (p.Pro129=) rs779324498
NM_032043.2(BRIP1):c.408A>C (p.Ala136=) rs876660891
NM_032043.2(BRIP1):c.430G>A (p.Ala144Thr) rs116952709
NM_032043.2(BRIP1):c.440dupA (p.Tyr147Terfs) rs786203521
NM_032043.2(BRIP1):c.465A>G (p.Gln155=) rs876659453
NM_032043.2(BRIP1):c.477_481delAAGAA (p.Lys159Asnfs) rs1555616143
NM_032043.2(BRIP1):c.484C>T (p.Arg162Ter) rs747604569
NM_032043.2(BRIP1):c.504G>A (p.Gln168=) rs1064795698
NM_032043.2(BRIP1):c.507G>A (p.Gln169=) rs876660937
NM_032043.2(BRIP1):c.517C>T (p.Arg173Cys) rs4988345
NM_032043.2(BRIP1):c.537A>G (p.Glu179=) rs775509896
NM_032043.2(BRIP1):c.56A>G (p.Tyr19Cys) rs876660880
NM_032043.2(BRIP1):c.577G>A (p.Val193Ile) rs4988346
NM_032043.2(BRIP1):c.584T>C (p.Leu195Pro) rs4988347
NM_032043.2(BRIP1):c.587A>G (p.Asn196Ser) rs550707862
NM_032043.2(BRIP1):c.612C>G (p.Ser204=) rs587780832
NM_032043.2(BRIP1):c.617C>T (p.Ser206Leu) rs565458815
NM_032043.2(BRIP1):c.618G>T (p.Ser206=) rs367614726
NM_032043.2(BRIP1):c.627+1G>A rs587780833
NM_032043.2(BRIP1):c.628C>T (p.Pro210Ser) rs150313156
NM_032043.2(BRIP1):c.636C>A (p.Gly212=) rs1057520255
NM_032043.2(BRIP1):c.679C>G (p.Gln227Glu) rs45459799
NM_032043.2(BRIP1):c.689C>T (p.Ser230Leu) rs759031349
NM_032043.2(BRIP1):c.702G>A (p.Lys234=) rs45512798
NM_032043.2(BRIP1):c.703_705delAAG (p.Lys235del) rs876659379
NM_032043.2(BRIP1):c.728T>C (p.Ile243Thr) rs587781860
NM_032043.2(BRIP1):c.751C>T (p.Arg251Cys) rs752309409
NM_032043.2(BRIP1):c.778A>G (p.Thr260Ala) rs138743097
NM_032043.2(BRIP1):c.78dup (p.Ala27Cysfs) rs1555618709
NM_032043.2(BRIP1):c.820A>G (p.Thr274Ala) rs62620988
NM_032043.2(BRIP1):c.840delT (p.His281Ilefs) rs1555609191
NM_032043.2(BRIP1):c.852C>T (p.Val284=) rs144940449
NM_032043.2(BRIP1):c.854A>G (p.His285Arg) rs141055990
NM_032043.2(BRIP1):c.890A>G (p.Lys297Arg) rs28997570
NM_032043.2(BRIP1):c.890delA (p.Lys297Serfs) rs786202610
NM_032043.2(BRIP1):c.897G>A (p.Met299Ile) rs137852985
NM_032043.2(BRIP1):c.917dup (p.Asn306Lysfs) rs1555609121
NM_032043.2(BRIP1):c.918+15T>A rs117820198
NM_032043.2(BRIP1):c.918+1G>A rs587781655
NM_032043.2(BRIP1):c.919-10T>G rs748497834
NM_032043.2(BRIP1):c.93+15G>A rs113052745
NM_032043.2(BRIP1):c.94-4A>G rs765154059

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