ClinVar Miner

Variants in gene CDH1 with conflicting interpretations

Y axis minimum submission review status: Y axis collection method:
X axis minimum submission review status: X axis collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than two submissions, it may have multiple conflicts and therefore be counted in more than one conflict column. If this is the case, the "Variants with any kind of conflict" cell will be less than the sum of the conflicted variants cells to its left.

Variants with only 1 submission per condition Variants with at least 2 submissions on the same condition and no conflicts Variants with a synonymous conflict
(e.g. benign vs non-pathogenic)
Variants with a confidence conflict
(e.g. benign vs likely benign)
Variants with a benign or likely benign vs uncertain conflict Variants with a category conflict
(e.g. benign vs affects)
Variants with a clinically significant conflict
(e.g. benign vs pathogenic)
Variants with any conflict
1974 467 3 115 93 1 8 193

Significance breakdown #

In the table below, cells that correspond to a term paired with itself represent synonymous conflicts, i.e. variants that have been annotated with different terms that map to the same standard term. To compare the terms that were actually submitted, check the box in the filters section at the top of this page.

pathogenic likely pathogenic uncertain significance likely benign benign drug response protective other
pathogenic 0 43 4 4 4 1 1 1
likely pathogenic 42 0 3 1 1 0 0 0
uncertain significance 3 3 2 83 24 0 0 0
likely benign 3 1 83 0 73 0 0 0
benign 3 1 24 73 1 0 0 0

All variants with conflicting interpretations #

Total variants: 193
Download table as spreadsheet
HGVS dbSNP
NC_000016.10:g.68835549T>A rs181705992
NM_004360.5(CDH1):c.*54C>T rs1801026
NM_004360.5(CDH1):c.*8G>A rs201223411
NM_004360.5(CDH1):c.-54G>C rs5030874
NM_004360.5(CDH1):c.-71C>G rs34033771
NM_004360.5(CDH1):c.-8G>C rs879449703
NM_004360.5(CDH1):c.1004G>A (p.Arg335Gln) rs373364873
NM_004360.5(CDH1):c.1008+8G>T rs990193541
NM_004360.5(CDH1):c.1008G>T (p.Glu336Asp) rs267606712
NM_004360.5(CDH1):c.1018A>G (p.Thr340Ala) rs116093741
NM_004360.5(CDH1):c.1019C>T (p.Thr340Met) rs61747631
NM_004360.5(CDH1):c.1020G>A (p.Thr340=) rs61747632
NM_004360.5(CDH1):c.103G>T (p.Glu35Ter)
NM_004360.5(CDH1):c.1118C>T (p.Pro373Leu) rs587782359
NM_004360.5(CDH1):c.1136C>T (p.Thr379Met) rs587782856
NM_004360.5(CDH1):c.1137+1G>A rs876660771
NM_004360.5(CDH1):c.1137+2T>C rs786202817
NM_004360.5(CDH1):c.1137G>A (p.Thr379=) rs587783050
NM_004360.5(CDH1):c.1138-3C>T rs36103202
NM_004360.5(CDH1):c.1145del (p.Gly382fs) rs1555515863
NM_004360.5(CDH1):c.1162G>A (p.Glu388Lys) rs372838203
NM_004360.5(CDH1):c.1170C>T (p.Asn390=) rs766505270
NM_004360.5(CDH1):c.1170del (p.Asn390fs) rs1567507724
NM_004360.5(CDH1):c.1174G>A (p.Val392Ile) rs141864044
NM_004360.5(CDH1):c.1223C>T (p.Ala408Val) rs138135866
NM_004360.5(CDH1):c.1224G>A (p.Ala408=) rs200161607
NM_004360.5(CDH1):c.1225T>C (p.Trp409Arg) rs587778176
NM_004360.5(CDH1):c.1239C>T (p.Tyr413=) rs36074916
NM_004360.5(CDH1):c.1243A>G (p.Ile415Val) rs1060501239
NM_004360.5(CDH1):c.1272C>T (p.Val424=) rs61756284
NM_004360.5(CDH1):c.1273G>A (p.Val425Ile) rs570930882
NM_004360.5(CDH1):c.1297G>A (p.Asp433Asn) rs199886166
NM_004360.5(CDH1):c.1298A>G (p.Asp433Gly) rs376097289
NM_004360.5(CDH1):c.1308G>A (p.Leu436=) rs557551011
NM_004360.5(CDH1):c.1314A>G (p.Thr438=) rs547316616
NM_004360.5(CDH1):c.1334A>C (p.Glu445Ala) rs374398608
NM_004360.5(CDH1):c.1353T>C (p.Ile451=) rs114192597
NM_004360.5(CDH1):c.1354_1357del (p.Leu452fs) rs886039612
NM_004360.5(CDH1):c.1359C>T (p.His453=) rs114861467
NM_004360.5(CDH1):c.1360G>A (p.Val454Ile) rs587780112
NM_004360.5(CDH1):c.1392C>T (p.Val464=) rs373811706
NM_004360.5(CDH1):c.1409C>T (p.Thr470Ile) rs370864592
NM_004360.5(CDH1):c.1416C>T (p.Thr472=) rs139937234
NM_004360.5(CDH1):c.1417G>A (p.Val473Ile) rs36087757
NM_004360.5(CDH1):c.1460_1461del (p.Val487fs) rs1567508939
NM_004360.5(CDH1):c.1493A>C (p.Asp498Ala) rs876661065
NM_004360.5(CDH1):c.1500C>T (p.Gly500=) rs781317341
NM_004360.5(CDH1):c.150C>A (p.Arg50=) rs786201262
NM_004360.5(CDH1):c.1530C>T (p.Ala510=) rs1597898262
NM_004360.5(CDH1):c.1565+1G>T rs587780113
NM_004360.5(CDH1):c.1565+2_1565+3insTT rs1555516200
NM_004360.5(CDH1):c.1565C>T (p.Thr522Ile) rs863224725
NM_004360.5(CDH1):c.1566-7C>T rs747783435
NM_004360.5(CDH1):c.1568A>G (p.Tyr523Cys) rs553907248
NM_004360.5(CDH1):c.1569T>A (p.Tyr523Ter) rs876659716
NM_004360.5(CDH1):c.1585A>G (p.Thr529Ala) rs776890776
NM_004360.5(CDH1):c.1587dup (p.Ala530fs) rs1555516532
NM_004360.5(CDH1):c.164T>G (p.Val55Gly) rs587778174
NM_004360.5(CDH1):c.1680G>C (p.Thr560=) rs35741240
NM_004360.5(CDH1):c.1684A>G (p.Thr562Ala) rs587782061
NM_004360.5(CDH1):c.1685C>G (p.Thr562Arg) rs587782381
NM_004360.5(CDH1):c.1689C>T (p.Ala563=) rs587780786
NM_004360.5(CDH1):c.1697T>C (p.Ile566Thr) rs763292288
NM_004360.5(CDH1):c.1711+5G>A rs1131690818
NM_004360.5(CDH1):c.1711+9G>A rs368770384
NM_004360.5(CDH1):c.1711+9G>C rs368770384
NM_004360.5(CDH1):c.1716T>C (p.Ser572=) rs876660176
NM_004360.5(CDH1):c.1744C>T (p.Leu582=) rs1801025
NM_004360.5(CDH1):c.1773C>T (p.Asn591=) rs373719554
NM_004360.5(CDH1):c.1774G>A (p.Ala592Thr) rs35187787
NM_004360.5(CDH1):c.1849G>A (p.Ala617Thr) rs33935154
NM_004360.5(CDH1):c.184G>A (p.Gly62Ser) rs587781898
NM_004360.5(CDH1):c.1888C>G (p.Leu630Val) rs2276331
NM_004360.5(CDH1):c.188G>A (p.Arg63Gln) rs587780117
NM_004360.5(CDH1):c.1895_1896del (p.His632fs) rs1060501224
NM_004360.5(CDH1):c.1896C>T (p.His632=) rs33969373
NM_004360.5(CDH1):c.1901C>T (p.Ala634Val) rs121964878
NM_004360.5(CDH1):c.1917_1918del (p.Ile640fs) rs1555516896
NM_004360.5(CDH1):c.1921C>T (p.Gln641Ter) rs587782750
NM_004360.5(CDH1):c.1937-13T>C rs2276330
NM_004360.5(CDH1):c.1942G>T (p.Glu648Ter) rs971882211
NM_004360.5(CDH1):c.1988A>G (p.Tyr663Cys) rs372182377
NM_004360.5(CDH1):c.2020A>T (p.Asn674Tyr) rs201637081
NM_004360.5(CDH1):c.202del (p.Tyr68fs) rs786202151
NM_004360.5(CDH1):c.2053G>A (p.Val685Met) rs550612843
NM_004360.5(CDH1):c.2077G>A (p.Gly693Ser) rs386833398
NM_004360.5(CDH1):c.2079C>T (p.Gly693=) rs771993728
NM_004360.5(CDH1):c.2080G>A (p.Val694Ile) rs587780118
NM_004360.5(CDH1):c.2091G>A (p.Lys697=) rs61747635
NM_004360.5(CDH1):c.2100del (p.Val701fs) rs1555517136
NM_004360.5(CDH1):c.2103C>T (p.Val701=) rs730881656
NM_004360.5(CDH1):c.2104G>A (p.Glu702Lys) rs149127230
NM_004360.5(CDH1):c.2104G>T (p.Glu702Ter) rs149127230
NM_004360.5(CDH1):c.2121T>C (p.Ile707=) rs764657974
NM_004360.5(CDH1):c.2131C>G (p.Leu711Val) rs121964871
NM_004360.5(CDH1):c.214G>A (p.Asp72Asn) rs35606263
NM_004360.5(CDH1):c.2164+3A>G rs750651204
NM_004360.5(CDH1):c.2165-15C>A rs552874184
NM_004360.5(CDH1):c.2195G>A (p.Arg732Gln) rs1060501244
NM_004360.5(CDH1):c.2272G>T (p.Glu758Ter) rs786202785
NM_004360.5(CDH1):c.2287G>T (p.Glu763Ter) rs587780787
NM_004360.5(CDH1):c.2292C>T (p.Asp764=) rs61747636
NM_004360.5(CDH1):c.2296-1G>A rs1057517542
NM_004360.5(CDH1):c.2322G>A (p.Arg774=) rs150734856
NM_004360.5(CDH1):c.2324del (p.Gly775fs) rs1060501248
NM_004360.5(CDH1):c.2329G>A (p.Asp777Asn) rs372989292
NM_004360.5(CDH1):c.2331C>T (p.Asp777=) rs114265540
NM_004360.5(CDH1):c.2336G>A (p.Arg779Gln) rs587781311
NM_004360.5(CDH1):c.2343A>G (p.Glu781=) rs587780119
NM_004360.5(CDH1):c.2343A>T (p.Glu781Asp) rs587780119
NM_004360.5(CDH1):c.2369C>T (p.Thr790Ile) rs587780120
NM_004360.5(CDH1):c.2374A>C (p.Met792Leu) rs759380419
NM_004360.5(CDH1):c.2386dup (p.Arg796fs) rs1375617541
NM_004360.5(CDH1):c.2387G>A (p.Arg796Gln) rs587782549
NM_004360.5(CDH1):c.2398del (p.Arg800fs) rs587783048
NM_004360.5(CDH1):c.2399G>A (p.Arg800His) rs370345996
NM_004360.5(CDH1):c.2412C>T (p.Pro804=) rs202075199
NM_004360.5(CDH1):c.2413G>A (p.Asp805Asn) rs200894246
NM_004360.5(CDH1):c.2430del (p.Phe810fs) rs786203752
NM_004360.5(CDH1):c.2439+10C>T rs35236080
NM_004360.5(CDH1):c.2440-6C>G rs139757930
NM_004360.5(CDH1):c.2440-6C>T rs139757930
NM_004360.5(CDH1):c.2450C>T (p.Ala817Val) rs587782024
NM_004360.5(CDH1):c.2451G>A (p.Ala817=) rs149450874
NM_004360.5(CDH1):c.2494G>A (p.Val832Met) rs35572355
NM_004360.5(CDH1):c.2505T>C (p.Tyr835=) rs786202613
NM_004360.5(CDH1):c.2512A>G (p.Ser838Gly) rs121964872
NM_004360.5(CDH1):c.2520C>T (p.Ser840=) rs140328601
NM_004360.5(CDH1):c.261del (p.Arg87fs) rs1555514429
NM_004360.5(CDH1):c.2634C>T (p.Gly878=) rs2229044
NM_004360.5(CDH1):c.2635G>A (p.Gly879Ser) rs200911775
NM_004360.5(CDH1):c.2637C>T (p.Gly879=) rs141001592
NM_004360.5(CDH1):c.2638G>A (p.Glu880Lys) rs34507583
NM_004360.5(CDH1):c.269G>A (p.Arg90Gln) rs587782647
NM_004360.5(CDH1):c.286A>G (p.Ile96Val) rs749306433
NM_004360.5(CDH1):c.303C>T (p.Tyr101=) rs150789339
NM_004360.5(CDH1):c.304G>A (p.Ala102Thr) rs368492235
NM_004360.5(CDH1):c.324A>G (p.Arg108=) rs116542018
NM_004360.5(CDH1):c.32TGC[6] (p.Leu15dup) rs587782476
NM_004360.5(CDH1):c.32TGC[7] (p.Leu14_Leu15dup) rs587782476
NM_004360.5(CDH1):c.33G>C (p.Leu11=) rs730881654
NM_004360.5(CDH1):c.344C>T (p.Thr115Met) rs370973869
NM_004360.5(CDH1):c.345G>A (p.Thr115=) rs1801023
NM_004360.5(CDH1):c.376_382dup (p.His128fs) rs1567501500
NM_004360.5(CDH1):c.382del (p.His128fs) rs1555514492
NM_004360.5(CDH1):c.387+5G>A rs113055163
NM_004360.5(CDH1):c.387+6T>C rs764434962
NM_004360.5(CDH1):c.393C>T (p.Ser131=) rs145430811
NM_004360.5(CDH1):c.394G>A (p.Val132Ile) rs142498771
NM_004360.5(CDH1):c.408A>G (p.Gln136=) rs1060501229
NM_004360.5(CDH1):c.457A>T (p.Lys153Ter) rs1567504575
NM_004360.5(CDH1):c.462A>G (p.Arg154=) rs1057520261
NM_004360.5(CDH1):c.467G>A (p.Trp156Ter) rs1555515215
NM_004360.5(CDH1):c.48+15_48+16del rs730881655
NM_004360.5(CDH1):c.48+5C>G rs77312180
NM_004360.5(CDH1):c.48+5C>T rs77312180
NM_004360.5(CDH1):c.48+6C>T rs3743674
NM_004360.5(CDH1):c.49-3C>T rs587782366
NM_004360.5(CDH1):c.49-8C>T rs774761552
NM_004360.5(CDH1):c.49-9C>A rs1555509752
NM_004360.5(CDH1):c.4G>A (p.Gly2Ser) rs786201212
NM_004360.5(CDH1):c.532-18C>T rs200673941
NM_004360.5(CDH1):c.546A>C (p.Lys182Asn) rs201141645
NM_004360.5(CDH1):c.570C>T (p.Tyr190=) rs761753486
NM_004360.5(CDH1):c.604G>A (p.Val202Ile) rs546716073
NM_004360.5(CDH1):c.656del (p.Pro219fs) rs1555515284
NM_004360.5(CDH1):c.670C>T (p.Arg224Cys) rs200310662
NM_004360.5(CDH1):c.671G>A (p.Arg224His) rs201511530
NM_004360.5(CDH1):c.671G>T (p.Arg224Leu) rs201511530
NM_004360.5(CDH1):c.687+1G>A rs1567504977
NM_004360.5(CDH1):c.688-4T>C rs781633588
NM_004360.5(CDH1):c.696_697del (p.His233fs) rs1060501214
NM_004360.5(CDH1):c.715G>A (p.Gly239Arg) rs587780537
NM_004360.5(CDH1):c.720del (p.Asn240fs) rs1131690819
NM_004360.5(CDH1):c.724G>A (p.Val242Ile) rs111662525
NM_004360.5(CDH1):c.731A>G (p.Asp244Gly) rs1064794231
NM_004360.5(CDH1):c.76G>T (p.Glu26Ter) rs786201058
NM_004360.5(CDH1):c.781G>T (p.Glu261Ter) rs121964873
NM_004360.5(CDH1):c.793G>T (p.Glu265Ter) rs876659503
NM_004360.5(CDH1):c.808T>G (p.Ser270Ala) rs587776399
NM_004360.5(CDH1):c.820G>A (p.Gly274Ser) rs781513008
NM_004360.5(CDH1):c.832+1G>A rs878854697
NM_004360.5(CDH1):c.832+9A>T rs1057521268
NM_004360.5(CDH1):c.833-3C>T rs587782839
NM_004360.5(CDH1):c.84C>T (p.Cys28=) rs587780789
NM_004360.5(CDH1):c.858C>A (p.Ala286=) rs876660354
NM_004360.5(CDH1):c.867G>A (p.Ala289=) rs754143182
NM_004360.5(CDH1):c.88C>A (p.Pro30Thr) rs139866691
NM_004360.5(CDH1):c.892G>A (p.Ala298Thr) rs142822590
NM_004360.5(CDH1):c.894C>T (p.Ala298=) rs139110184
NM_004360.5(CDH1):c.8C>G (p.Pro3Arg) rs587782484
NM_004360.5(CDH1):c.933C>G (p.Leu311=) rs35539711
Single allele

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