ClinVar Miner

Variants in gene CTNNA3 with conflicting interpretations

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Y axis minimum submission review status: Y axis collection method:
X axis minimum submission review status: X axis collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than two submissions, it may have multiple conflicts and therefore be counted in more than one conflict column. If this is the case, the "Variants with any kind of conflict" cell will be less than the sum of the conflicted variants cells to its left.

Variants with only 1 submission per condition Variants with at least 2 submissions on the same condition and no conflicts Variants with a synonymous conflict
(e.g. benign vs non-pathogenic)
Variants with a confidence conflict
(e.g. benign vs likely benign)
Variants with a benign or likely benign vs uncertain conflict Variants with a category conflict
(e.g. benign vs affects)
Variants with a clinically significant conflict
(e.g. benign vs pathogenic)
Variants with any conflict
871 51 0 29 8 0 0 36

Significance breakdown #

In the table below, cells that correspond to a term paired with itself represent synonymous conflicts, i.e. variants that have been annotated with different terms that map to the same standard term. To compare the terms that were actually submitted, check the box in the filters section at the top of this page.

uncertain significance likely benign benign
uncertain significance 0 8 0
likely benign 8 0 29
benign 0 29 0

All variants with conflicting interpretations #

Total variants: 36
Download table as spreadsheet
HGVS dbSNP gnomAD frequency
NM_013266.4(CTNNA3):c.1787G>A (p.Ser596Asn) rs4548513 0.47526
NM_013266.4(CTNNA3):c.1655C>T (p.Thr552Met) rs61737718 0.02389
NM_013266.4(CTNNA3):c.478T>A (p.Ser160Thr) rs61749223 0.01916
NM_013266.4(CTNNA3):c.1603C>T (p.Arg535Cys) rs41274090 0.01060
NM_013266.4(CTNNA3):c.2553G>A (p.Lys851=) rs115814032 0.00420
NM_013266.4(CTNNA3):c.99+11C>T rs115451937 0.00411
NM_013266.4(CTNNA3):c.2142G>A (p.Glu714=) rs115972723 0.00315
NM_013266.4(CTNNA3):c.1611G>A (p.Ala537=) rs146900023 0.00266
NM_013266.4(CTNNA3):c.483C>T (p.Leu161=) rs74142830 0.00255
NM_013266.4(CTNNA3):c.1133G>A (p.Arg378His) rs143682596 0.00240
NM_013266.4(CTNNA3):c.33C>T (p.Ile11=) rs61735044 0.00206
NM_013266.4(CTNNA3):c.2172A>C (p.Pro724=) rs116662854 0.00191
NM_013266.4(CTNNA3):c.1195C>A (p.Leu399Ile) rs115276158 0.00178
NM_013266.4(CTNNA3):c.429T>C (p.Asp143=) rs111880127 0.00178
NM_013266.4(CTNNA3):c.580-8C>T rs141983252 0.00170
NM_013266.4(CTNNA3):c.2158A>C (p.Arg720=) rs143867269 0.00169
NM_013266.4(CTNNA3):c.1453A>T (p.Thr485Ser) rs140913916 0.00130
NM_013266.4(CTNNA3):c.1936C>T (p.Arg646Cys) rs111425421 0.00116
NM_013266.4(CTNNA3):c.844-15G>A rs201089736 0.00098
NM_013266.4(CTNNA3):c.1900G>A (p.Glu634Lys) rs77165728 0.00058
NM_013266.4(CTNNA3):c.1929C>T (p.His643=) rs147760277 0.00055
NM_013266.4(CTNNA3):c.2524C>T (p.Arg842Trp) rs199852825 0.00034
NM_013266.4(CTNNA3):c.1192G>A (p.Val398Ile) rs145043626 0.00028
NM_013266.4(CTNNA3):c.387G>A (p.Leu129=) rs143943926 0.00026
NM_013266.4(CTNNA3):c.2601G>A (p.Thr867=) rs575703238 0.00022
NM_013266.4(CTNNA3):c.779A>G (p.Gln260Arg) rs190073606 0.00022
NM_013266.4(CTNNA3):c.18A>T (p.Pro6=) rs138580439 0.00018
NM_013266.4(CTNNA3):c.718A>G (p.Thr240Ala) rs367570454 0.00016
NM_013266.4(CTNNA3):c.1231A>G (p.Ile411Val) rs372808360 0.00011
NM_013266.4(CTNNA3):c.1303A>G (p.Met435Val) rs377404952 0.00011
NM_013266.4(CTNNA3):c.1732+8A>G rs372686443 0.00011
NM_013266.4(CTNNA3):c.399G>A (p.Thr133=) rs150376558 0.00009
NM_013266.4(CTNNA3):c.2404G>T (p.Asp802Tyr) rs530727340 0.00004
NM_013266.4(CTNNA3):c.1248G>A (p.Ala416=) rs1046657762 0.00002
NM_013266.4(CTNNA3):c.1836G>A (p.Lys612=) rs774209973
NM_013266.4(CTNNA3):c.2401-23dup rs1338241471

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