ClinVar Miner

Variants in gene CUL7 with conflicting interpretations

Y axis minimum submission review status: Y axis collection method:
X axis minimum submission review status: X axis collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than two submissions, it may have multiple conflicts and therefore be counted in more than one conflict column. If this is the case, the "Variants with any kind of conflict" cell will be less than the sum of the conflicted variants cells to its left.

Variants with only 1 submission per condition Variants with at least 2 submissions on the same condition and no conflicts Variants with a synonymous conflict
(e.g. benign vs non-pathogenic)
Variants with a confidence conflict
(e.g. benign vs likely benign)
Variants with a benign or likely benign vs uncertain conflict Variants with a category conflict
(e.g. benign vs affects)
Variants with a clinically significant conflict
(e.g. benign vs pathogenic)
Variants with any conflict
235 23 0 5 13 0 1 18

Significance breakdown #

In the table below, cells that correspond to a term paired with itself represent synonymous conflicts, i.e. variants that have been annotated with different terms that map to the same standard term. To compare the terms that were actually submitted, check the box in the filters section at the top of this page.

likely pathogenic uncertain significance likely benign benign
likely pathogenic 0 1 0 0
uncertain significance 1 0 11 3
likely benign 0 11 0 5
benign 0 3 5 0

All variants with conflicting interpretations #

Total variants: 18
Download table as spreadsheet
HGVS dbSNP
NM_014780.4(CUL7):c.1067G>A (p.Arg356His) rs146227929
NM_014780.4(CUL7):c.136C>T (p.Arg46Trp) rs141692693
NM_014780.4(CUL7):c.1846A>G (p.Ser616Gly) rs7774330
NM_014780.4(CUL7):c.1859C>T (p.Pro620Leu) rs147326417
NM_014780.4(CUL7):c.2115C>T (p.His705=) rs143128153
NM_014780.4(CUL7):c.2163T>C (p.Asp721=) rs145572983
NM_014780.4(CUL7):c.2645G>A (p.Arg882Gln) rs45574335
NM_014780.4(CUL7):c.2754G>A (p.Thr918=) rs138777262
NM_014780.4(CUL7):c.2802C>A (p.Leu934=) rs144926293
NM_014780.4(CUL7):c.3041T>G (p.Leu1014Arg) rs61752334
NM_014780.4(CUL7):c.3432G>A (p.Thr1144=) rs144556973
NM_014780.4(CUL7):c.3490C>T (p.Arg1164Trp) rs201135654
NM_014780.4(CUL7):c.3747G>A (p.Leu1249=) rs141211365
NM_014780.4(CUL7):c.3876C>T (p.Ile1292=) rs147056081
NM_014780.4(CUL7):c.4659G>A (p.Glu1553=) rs139243761
NM_014780.4(CUL7):c.4914C>T (p.Asp1638=) rs61731584
NM_014780.4(CUL7):c.861G>A (p.Gly287=) rs61750322
NM_014780.4(CUL7):c.981C>T (p.Pro327=) rs144880219

The information on this website is not intended for direct diagnostic use or medical decision-making without review by a genetics professional. Individuals should not change their health behavior solely on the basis of information contained on this website. Neither the University of Utah nor the National Institutes of Health independently verfies the submitted information. If you have questions about the information contained on this website, please see a health care professional.