ClinVar Miner

Variants in gene DDX3X with conflicting interpretations

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Y axis minimum submission review status: Y axis collection method:
X axis minimum submission review status: X axis collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than two submissions, it may have multiple conflicts and therefore be counted in more than one conflict column. If this is the case, the "Variants with any kind of conflict" cell will be less than the sum of the conflicted variants cells to its left.

Variants with only 1 submission per condition Variants with at least 2 submissions on the same condition and no conflicts Variants with a synonymous conflict
(e.g. benign vs non-pathogenic)
Variants with a confidence conflict
(e.g. benign vs likely benign)
Variants with a benign or likely benign vs uncertain conflict Variants with a category conflict
(e.g. benign vs affects)
Variants with a clinically significant conflict
(e.g. benign vs pathogenic)
Variants with any conflict
639 39 0 34 7 0 6 45

Significance breakdown #

In the table below, cells that correspond to a term paired with itself represent synonymous conflicts, i.e. variants that have been annotated with different terms that map to the same standard term. To compare the terms that were actually submitted, check the box in the filters section at the top of this page.

pathogenic likely pathogenic uncertain significance likely benign benign
pathogenic 0 21 4 0 0
likely pathogenic 21 0 4 0 0
uncertain significance 4 4 0 6 1
likely benign 0 0 6 0 13
benign 0 0 1 13 0

All variants with conflicting interpretations #

Total variants: 45
Download table as spreadsheet
HGVS dbSNP gnomAD frequency
NM_001356.5(DDX3X):c.104-10A>T rs112766093 0.00708
NM_001356.5(DDX3X):c.969T>C (p.Thr323=) rs368366114 0.00073
NM_001356.5(DDX3X):c.1434G>A (p.Arg478=) rs186110059 0.00026
NM_001356.5(DDX3X):c.1593T>C (p.Arg531=) rs761401204 0.00011
NM_001356.5(DDX3X):c.1497+5G>A rs201687537 0.00010
NM_001356.5(DDX3X):c.426A>C (p.Pro142=) rs779721240 0.00010
NM_001356.5(DDX3X):c.1095C>T (p.Val365=) rs546763977 0.00006
NM_001356.5(DDX3X):c.159C>T (p.Tyr53=) rs370574418 0.00004
NM_001356.5(DDX3X):c.1315+5C>T rs368731454 0.00002
NM_001356.5(DDX3X):c.251T>G (p.Phe84Cys) rs892274119 0.00002
NM_001356.5(DDX3X):c.1170+4C>T rs745429365 0.00001
NM_001356.5(DDX3X):c.1527T>C (p.Asn509=) rs368642919 0.00001
NM_001356.5(DDX3X):c.181A>G (p.Ser61Gly) rs778806111 0.00001
NM_001356.5(DDX3X):c.104-3dup rs772419774
NM_001356.5(DDX3X):c.1052G>A (p.Arg351Gln) rs1057518707
NM_001356.5(DDX3X):c.1126C>T (p.Arg376Cys) rs796052231
NM_001356.5(DDX3X):c.113A>G (p.Tyr38Cys) rs1555951993
NM_001356.5(DDX3X):c.1203C>T (p.Ile401=)
NM_001356.5(DDX3X):c.121C>T (p.Pro41Ser) rs1064793796
NM_001356.5(DDX3X):c.1227C>T (p.Gly409=)
NM_001356.5(DDX3X):c.1423C>G (p.Arg475Gly) rs1064794574
NM_001356.5(DDX3X):c.1423C>T (p.Arg475Cys) rs1064794574
NM_001356.5(DDX3X):c.1462C>T (p.Arg488Cys) rs796052234
NM_001356.5(DDX3X):c.1463G>A (p.Arg488His) rs796052235
NM_001356.5(DDX3X):c.1486G>A (p.Val496Met) rs1555954154
NM_001356.5(DDX3X):c.1541T>C (p.Ile514Thr) rs796052226
NM_001356.5(DDX3X):c.1582C>T (p.Arg528Cys) rs1064795323
NM_001356.5(DDX3X):c.1595C>T (p.Thr532Met) rs1064795387
NM_001356.5(DDX3X):c.1600C>T (p.Arg534Cys) rs1555954284
NM_001356.5(DDX3X):c.1616-4_1616-3del rs751868529
NM_001356.5(DDX3X):c.1675CTT[1] (p.Leu560del) rs1555954380
NM_001356.5(DDX3X):c.1676T>A (p.Leu559His) rs1064794993
NM_001356.5(DDX3X):c.173C>G (p.Ser58Ter) rs1602126980
NM_001356.5(DDX3X):c.1769G>A (p.Ser590Asn)
NM_001356.5(DDX3X):c.1807C>T (p.Arg603Ter) rs886041705
NM_001356.5(DDX3X):c.1815_1817del (p.Ser606del) rs2063940085
NM_001356.5(DDX3X):c.285-14_285-11del rs751523291
NM_001356.5(DDX3X):c.454dup (p.Ser152fs)
NM_001356.5(DDX3X):c.577G>T (p.Gly193Ter) rs875989803
NM_001356.5(DDX3X):c.596G>A (p.Arg199His)
NM_001356.5(DDX3X):c.744C>T (p.Gly248=) rs1569238002
NM_001356.5(DDX3X):c.788G>A (p.Arg263His) rs867967504
NM_001356.5(DDX3X):c.830_831del (p.Glu277fs) rs1602131859
NM_001356.5(DDX3X):c.874C>T (p.Arg292Ter) rs1555953488
NM_001356.5(DDX3X):c.959TAG[1] (p.Val321del) rs1555953527

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