ClinVar Miner

Variants in gene DOCK6 with conflicting interpretations

See also:
Y axis minimum submission review status: Y axis collection method:
X axis minimum submission review status: X axis collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than two submissions, it may have multiple conflicts and therefore be counted in more than one conflict column. If this is the case, the "Variants with any kind of conflict" cell will be less than the sum of the conflicted variants cells to its left.

Variants with only 1 submission per condition Variants with at least 2 submissions on the same condition and no conflicts Variants with a synonymous conflict
(e.g. benign vs non-pathogenic)
Variants with a confidence conflict
(e.g. benign vs likely benign)
Variants with a benign or likely benign vs uncertain conflict Variants with a category conflict
(e.g. benign vs affects)
Variants with a clinically significant conflict
(e.g. benign vs pathogenic)
Variants with any conflict
1119 99 0 54 12 0 0 64

Significance breakdown #

In the table below, cells that correspond to a term paired with itself represent synonymous conflicts, i.e. variants that have been annotated with different terms that map to the same standard term. To compare the terms that were actually submitted, check the box in the filters section at the top of this page.

pathogenic likely pathogenic uncertain significance likely benign benign
pathogenic 0 3 0 0 0
likely pathogenic 3 0 0 0 0
uncertain significance 0 0 0 12 2
likely benign 0 0 12 0 51
benign 0 0 2 51 0

All variants with conflicting interpretations #

Total variants: 64
Download table as spreadsheet
HGVS dbSNP gnomAD frequency
NM_020812.4(DOCK6):c.4895C>T (p.Ala1632Val) rs117328686 0.02223
NM_020812.4(DOCK6):c.2956-5C>T rs3810309 0.01873
NM_020812.4(DOCK6):c.4258G>C (p.Val1420Leu) rs8108071 0.01108
NM_020812.4(DOCK6):c.1992C>T (p.His664=) rs116286520 0.01079
NM_020812.4(DOCK6):c.441G>C (p.Lys147Asn) rs34545822 0.00959
NM_020812.4(DOCK6):c.3913C>T (p.Arg1305Cys) rs112911897 0.00801
NM_020812.4(DOCK6):c.1833-8T>A rs7252321 0.00708
NM_020812.4(DOCK6):c.5700G>A (p.Thr1900=) rs142270471 0.00651
NM_020812.4(DOCK6):c.4933G>A (p.Val1645Ile) rs34853494 0.00645
NM_020812.4(DOCK6):c.434G>A (p.Arg145Gln) rs140883567 0.00446
NM_020812.4(DOCK6):c.4205C>T (p.Thr1402Met) rs147554257 0.00411
NM_020812.4(DOCK6):c.2160+5G>A rs150276162 0.00405
NM_020812.4(DOCK6):c.4344G>A (p.Pro1448=) rs200307398 0.00331
NM_020812.4(DOCK6):c.4197C>T (p.Ile1399=) rs35583018 0.00306
NM_020812.4(DOCK6):c.1959C>T (p.Pro653=) rs200269584 0.00273
NM_020812.4(DOCK6):c.4899G>A (p.Leu1633=) rs72985308 0.00255
NM_020812.4(DOCK6):c.5229C>A (p.Gly1743=) rs56243833 0.00246
NM_020812.4(DOCK6):c.3752G>A (p.Arg1251Gln) rs200390354 0.00245
NM_020812.4(DOCK6):c.3526T>C (p.Leu1176=) rs200883815 0.00235
NM_020812.4(DOCK6):c.630G>A (p.Ala210=) rs114634227 0.00214
NM_020812.4(DOCK6):c.5976T>A (p.Ile1992=) rs200181665 0.00201
NM_020812.4(DOCK6):c.4479C>T (p.Phe1493=) rs146048288 0.00173
NM_020812.4(DOCK6):c.4862T>C (p.Val1621Ala) rs201738818 0.00166
NM_020812.4(DOCK6):c.5939+6C>T rs200393834 0.00149
NM_020812.4(DOCK6):c.1993G>A (p.Gly665Arg) rs17001264 0.00148
NM_020812.4(DOCK6):c.133G>A (p.Val45Ile) rs183060698 0.00141
NM_020812.4(DOCK6):c.810C>T (p.Phe270=) rs372611420 0.00140
NM_020812.4(DOCK6):c.4869G>A (p.Ala1623=) rs187249194 0.00107
NM_020812.4(DOCK6):c.2104G>A (p.Gly702Ser) rs199838752 0.00102
NM_020812.4(DOCK6):c.1608C>T (p.Pro536=) rs114902682 0.00096
NM_020812.4(DOCK6):c.2594G>A (p.Arg865His) rs199922090 0.00094
NM_020812.4(DOCK6):c.5582G>A (p.Arg1861His) rs115035890 0.00093
NM_020812.4(DOCK6):c.2883C>T (p.Pro961=) rs370648857 0.00073
NM_020812.4(DOCK6):c.4548G>A (p.Thr1516=) rs377755210 0.00064
NM_020812.4(DOCK6):c.729C>G (p.Ala243=) rs35674395 0.00061
NM_020812.4(DOCK6):c.518G>A (p.Arg173Gln) rs373956807 0.00053
NM_020812.4(DOCK6):c.4107-13T>A rs369430502 0.00046
NM_020812.4(DOCK6):c.5088+8C>G rs147181483 0.00042
NM_020812.4(DOCK6):c.1643+5G>A rs117014874 0.00037
NM_020812.4(DOCK6):c.3873C>T (p.Cys1291=) rs200843111 0.00019
NM_020812.4(DOCK6):c.5832+5G>A rs181867999 0.00019
NM_020812.4(DOCK6):c.5939+2T>C rs201387914 0.00019
NM_020812.4(DOCK6):c.1761+6T>C rs200659753 0.00016
NM_020812.4(DOCK6):c.2506G>A (p.Val836Ile) rs200935357 0.00011
NM_020812.4(DOCK6):c.2103C>T (p.Asp701=) rs372208548 0.00006
NM_020812.4(DOCK6):c.4253A>G (p.Lys1418Arg) rs530689577 0.00006
NM_020812.4(DOCK6):c.4446C>T (p.Ser1482=) rs529459880 0.00006
NM_020812.4(DOCK6):c.12C>G (p.Ser4=) rs560244093 0.00005
NM_020812.4(DOCK6):c.258G>T (p.Leu86=) rs563605363 0.00003
NM_020812.4(DOCK6):c.4350G>C (p.Leu1450=) rs763073235 0.00002
NM_020812.4(DOCK6):c.3562C>T (p.Gln1188Ter) rs372751467 0.00001
NM_020812.4(DOCK6):c.1362_1365del (p.Thr455fs) rs730882238
NM_020812.4(DOCK6):c.172G>T (p.Asp58Tyr)
NM_020812.4(DOCK6):c.2140G>A (p.Val714Met)
NM_020812.4(DOCK6):c.2346G>A (p.Lys782=)
NM_020812.4(DOCK6):c.2550G>C (p.Pro850=) rs73506659
NM_020812.4(DOCK6):c.2772C>G (p.Arg924=) rs201482446
NM_020812.4(DOCK6):c.3163G>A (p.Val1055Met) rs202209921
NM_020812.4(DOCK6):c.5469G>A (p.Thr1823=)
NM_020812.4(DOCK6):c.5832+4C>T rs572880984
NM_020812.4(DOCK6):c.906G>C (p.Ser302=) rs79202547
NM_020812.4(DOCK6):c.945C>T (p.His315=)

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