ClinVar Miner

Variants in gene DOCK8 with conflicting interpretations

Y axis minimum submission review status: Y axis collection method:
X axis minimum submission review status: X axis collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than two submissions, it may have multiple conflicts and therefore be counted in more than one conflict column. If this is the case, the "Variants with any kind of conflict" cell will be less than the sum of the conflicted variants cells to its left.

Variants with only 1 submission per condition Variants with at least 2 submissions on the same condition and no conflicts Variants with a synonymous conflict
(e.g. benign vs non-pathogenic)
Variants with a confidence conflict
(e.g. benign vs likely benign)
Variants with a benign or likely benign vs uncertain conflict Variants with a category conflict
(e.g. benign vs affects)
Variants with a clinically significant conflict
(e.g. benign vs pathogenic)
Variants with any conflict
975 98 0 12 32 0 2 41

Significance breakdown #

In the table below, cells that correspond to a term paired with itself represent synonymous conflicts, i.e. variants that have been annotated with different terms that map to the same standard term. To compare the terms that were actually submitted, check the box in the filters section at the top of this page.

pathogenic likely pathogenic uncertain significance likely benign benign
pathogenic 0 1 2 0 0
likely pathogenic 1 0 1 0 0
uncertain significance 2 1 0 23 12
likely benign 0 0 23 0 11
benign 0 0 12 11 0

All variants with conflicting interpretations #

Total variants: 41
Download table as spreadsheet
GRCh38/hg38 9p24.3(chr9:204193-295405)x3
GRCh38/hg38 9p24.3(chr9:204193-381489)x3
NM_203447.3(DOCK8):c.1098G>A (p.Thr366=) rs139297216
NM_203447.3(DOCK8):c.1582C>A (p.Leu528Met) rs146250176
NM_203447.3(DOCK8):c.1881T>C (p.Phe627=) rs140134223
NM_203447.3(DOCK8):c.2971-4G>A rs186097329
NM_203447.3(DOCK8):c.3058A>G (p.Ile1020Val) rs151094543
NM_203447.3(DOCK8):c.3195G>A (p.Arg1065=) rs781062154
NM_203447.3(DOCK8):c.3220C>A (p.His1074Asn) rs150298985
NM_203447.3(DOCK8):c.3263C>T (p.Thr1088Met) rs149065013
NM_203447.3(DOCK8):c.3270T>C (p.Ile1090=) rs377297446
NM_203447.3(DOCK8):c.3519C>T (p.Ala1173=) rs144299704
NM_203447.3(DOCK8):c.3606T>C (p.Cys1202=) rs143919622
NM_203447.3(DOCK8):c.378C>G (p.Ile126Met) rs141175202
NM_203447.3(DOCK8):c.380G>A (p.Arg127His) rs150742426
NM_203447.3(DOCK8):c.3813A>G (p.Lys1271=) rs75411647
NM_203447.3(DOCK8):c.3988C>G (p.Leu1330Val) rs148081681
NM_203447.3(DOCK8):c.405-8C>G rs748853895
NM_203447.3(DOCK8):c.4158C>T (p.Asn1386=) rs77803650
NM_203447.3(DOCK8):c.452G>A (p.Arg151Gln) rs149918318
NM_203447.3(DOCK8):c.4724G>A (p.Arg1575Lys) rs141252560
NM_203447.3(DOCK8):c.5155G>A (p.Ala1719Thr) rs144279637
NM_203447.3(DOCK8):c.53+10C>T rs763565243
NM_203447.3(DOCK8):c.5355+6C>T rs188141951
NM_203447.3(DOCK8):c.5386C>T (p.Arg1796Ter) rs775544616
NM_203447.3(DOCK8):c.54-1G>T rs192864327
NM_203447.3(DOCK8):c.541C>G (p.His181Asp) rs200684000
NM_203447.3(DOCK8):c.550G>A (p.Val184Met) rs143461644
NM_203447.3(DOCK8):c.5892C>T (p.Asn1964=) rs138617736
NM_203447.3(DOCK8):c.5962-9T>C rs1324502895
NM_203447.3(DOCK8):c.6201A>G (p.Glu2067=) rs145573166
NM_203447.3(DOCK8):c.663C>A (p.Asp221Glu) rs139391329
NM_203447.4(DOCK8):c.1782T>C (p.Ala594=)
NM_203447.4(DOCK8):c.3022C>T (p.Arg1008Trp) rs16937932
NM_203447.4(DOCK8):c.3460C>T rs34390308
NM_203447.4(DOCK8):c.3543A>G (p.Val1181=) rs753242273
NM_203447.4(DOCK8):c.3573C>T (p.Ser1191=) rs13285348
NM_203447.4(DOCK8):c.3840+3A>G rs16938572
NM_203447.4(DOCK8):c.4019A>G (p.Tyr1340Cys) rs116920018
NM_203447.4(DOCK8):c.4024-4C>T rs111306749
NM_203447.4(DOCK8):c.6120G>A (p.Arg2040=)

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