ClinVar Miner

Variants in gene DOCK8 with conflicting interpretations

Y axis minimum submission review status: Y axis collection method:
X axis minimum submission review status: X axis collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than two submissions, it may have multiple conflicts and therefore be counted in more than one conflict column. If this is the case, the "Variants with any kind of conflict" cell will be less than the sum of the conflicted variants cells to its left.

Variants with only 1 submission Variants with at least 2 submissions and no conflicts Variants with a synonymous conflict
(e.g. benign vs non-pathogenic)
Variants with a confidence conflict
(e.g. benign vs likely benign)
Variants with a benign or likely benign vs uncertain conflict Variants with a category conflict
(e.g. benign vs affects)
Variants with a clinically significant conflict
(e.g. benign vs pathogenic)
Variants with any kind of conflict
312 46 0 29 24 0 1 48

Significance breakdown #

In the table below, cells that correspond to a term paired with itself represent synonymous conflicts, i.e. variants that have been annotated with different terms that map to the same standard term. To compare the terms that were actually submitted, check the box in the filters section at the top of this page.

pathogenic likely pathogenic uncertain significance likely benign benign
pathogenic 0 1 1 0 0
likely pathogenic 1 0 0 0 0
uncertain significance 1 0 0 14 16
likely benign 0 0 14 0 28
benign 0 0 16 28 0

All variants with conflicting interpretations #

Total variants: 48
Download table as spreadsheet
HGVS dbSNP
GRCh38/hg38 9p24.3(chr9:204193-295405)x3
GRCh38/hg38 9p24.3(chr9:204193-381489)x3
NM_001193536.1(DOCK8):c.3815A>G (p.Tyr1272Cys) rs116920018
NM_203447.3(DOCK8):c.1017G>A (p.Pro339=) rs35746964
NM_203447.3(DOCK8):c.1582C>A (p.Leu528Met) rs146250176
NM_203447.3(DOCK8):c.1587C>G (p.Pro529=) rs146289269
NM_203447.3(DOCK8):c.1790C>T (p.Ala597Val) rs17673268
NM_203447.3(DOCK8):c.187G>A (p.Asp63Asn) rs3209441
NM_203447.3(DOCK8):c.1881T>C (p.Phe627=) rs140134223
NM_203447.3(DOCK8):c.2295C>T (p.Ser765=) rs12348944
NM_203447.3(DOCK8):c.2739C>T (p.Ser913=) rs116523732
NM_203447.3(DOCK8):c.2862A>T (p.Pro954=) rs117610764
NM_203447.3(DOCK8):c.3021T>C (p.Phe1007=) rs7034926
NM_203447.3(DOCK8):c.3022C>T (p.Arg1008Trp) rs16937932
NM_203447.3(DOCK8):c.3058A>G (p.Ile1020Val) rs151094543
NM_203447.3(DOCK8):c.3208A>G (p.Asn1070Asp) rs73382631
NM_203447.3(DOCK8):c.3230G>A (p.Ser1077Asn) rs34627722
NM_203447.3(DOCK8):c.3263C>T (p.Thr1088Met) rs149065013
NM_203447.3(DOCK8):c.3441C>T (p.Phe1147=) rs34621129
NM_203447.3(DOCK8):c.3460C>T (p.Arg1154Cys) rs34390308
NM_203447.3(DOCK8):c.3543A>G (p.Val1181=) rs753242273
NM_203447.3(DOCK8):c.3565A>G (p.Ile1189Val) rs77399114
NM_203447.3(DOCK8):c.3606T>C (p.Cys1202=) rs143919622
NM_203447.3(DOCK8):c.380G>A (p.Arg127His) rs150742426
NM_203447.3(DOCK8):c.3813A>G (p.Lys1271=) rs75411647
NM_203447.3(DOCK8):c.3840+3A>G rs16938572
NM_203447.3(DOCK8):c.4024-4C>T rs111306749
NM_203447.3(DOCK8):c.404+16delT rs727505303
NM_203447.3(DOCK8):c.405-8C>G rs748853895
NM_203447.3(DOCK8):c.4346C>T (p.Ser1449Leu) rs370123223
NM_203447.3(DOCK8):c.452G>A (p.Arg151Gln) rs149918318
NM_203447.3(DOCK8):c.5001C>T (p.His1667=) rs35662752
NM_203447.3(DOCK8):c.5187A>G (p.Val1729=) rs111535933
NM_203447.3(DOCK8):c.5211G>A (p.Glu1737=) rs34098809
NM_203447.3(DOCK8):c.528+13A>G rs116483820
NM_203447.3(DOCK8):c.52A>G (p.Arg18Gly) rs200689054
NM_203447.3(DOCK8):c.5386C>T (p.Arg1796Ter)
NM_203447.3(DOCK8):c.54-1G>T rs192864327
NM_203447.3(DOCK8):c.5491-7T>A rs184867151
NM_203447.3(DOCK8):c.5818-14C>T rs10124592
NM_203447.3(DOCK8):c.5832G>A (p.Pro1944=) rs10491684
NM_203447.3(DOCK8):c.5908G>C (p.Ala1970Pro) rs34908836
NM_203447.3(DOCK8):c.6201A>G (p.Glu2067=) rs145573166
NM_203447.3(DOCK8):c.663C>A (p.Asp221Glu) rs139391329
NM_203447.3(DOCK8):c.709G>A (p.Glu237Lys) rs11789099
NM_203447.3(DOCK8):c.870C>G (p.Leu290=) rs201244929
NM_203447.3(DOCK8):c.952G>A (p.Ala318Thr) rs35482838
NM_203447.3(DOCK8):c.986C>T (p.Ala329Val) rs75352090

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