ClinVar Miner

Variants in gene EPHB4 with conflicting interpretations

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Y axis minimum submission review status: Y axis collection method:
X axis minimum submission review status: X axis collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than two submissions, it may have multiple conflicts and therefore be counted in more than one conflict column. If this is the case, the "Variants with any kind of conflict" cell will be less than the sum of the conflicted variants cells to its left.

Variants with only 1 submission per condition Variants with at least 2 submissions on the same condition and no conflicts Variants with a synonymous conflict
(e.g. benign vs non-pathogenic)
Variants with a confidence conflict
(e.g. benign vs likely benign)
Variants with a benign or likely benign vs uncertain conflict Variants with a category conflict
(e.g. benign vs affects)
Variants with a clinically significant conflict
(e.g. benign vs pathogenic)
Variants with any conflict
484 78 0 20 23 0 4 45

Significance breakdown #

In the table below, cells that correspond to a term paired with itself represent synonymous conflicts, i.e. variants that have been annotated with different terms that map to the same standard term. To compare the terms that were actually submitted, check the box in the filters section at the top of this page.

pathogenic likely pathogenic uncertain significance likely benign benign
pathogenic 0 5 4 0 0
likely pathogenic 5 0 0 0 0
uncertain significance 4 0 0 21 4
likely benign 0 0 21 0 15
benign 0 0 4 15 0

All variants with conflicting interpretations #

Total variants: 45
Download table as spreadsheet
HGVS dbSNP gnomAD frequency
NM_004444.5(EPHB4):c.1144G>A (p.Gly382Ser) rs114926839 0.00239
NM_004444.5(EPHB4):c.1593C>T (p.Ser531=) rs55682161 0.00155
NM_004444.5(EPHB4):c.691C>T (p.Pro231Ser) rs147563837 0.00077
NM_004444.5(EPHB4):c.1692-6C>A rs202035530 0.00052
NM_004444.5(EPHB4):c.1384G>A (p.Gly462Arg) rs146674844 0.00036
NM_004444.5(EPHB4):c.918C>T (p.Val306=) rs151161414 0.00036
NM_004444.5(EPHB4):c.1017G>T (p.Leu339=) rs55867842 0.00034
NM_004444.5(EPHB4):c.1079G>A (p.Arg360His) rs202006098 0.00026
NM_004444.5(EPHB4):c.1067C>G (p.Thr356Ser) rs192640017 0.00021
NM_004444.5(EPHB4):c.2955G>A (p.Pro985=) rs56086910 0.00014
NM_004444.5(EPHB4):c.935G>A (p.Arg312His) rs765819602 0.00008
NM_004444.5(EPHB4):c.1373G>A (p.Arg458Gln) rs542863867 0.00007
NM_004444.5(EPHB4):c.1054C>T (p.Arg352Ter) rs898898802 0.00004
NM_004444.5(EPHB4):c.2704C>T (p.Arg902Trp) rs200953030 0.00002
NM_004444.5(EPHB4):c.2767A>G (p.Arg923Gly) rs753634998 0.00002
NM_004444.5(EPHB4):c.2930C>T (p.Pro977Leu) rs773050327 0.00001
NM_004444.5(EPHB4):c.687C>T (p.Pro229=) rs560526074 0.00001
NM_004444.5(EPHB4):c.1151G>A (p.Arg384Gln)
NM_004444.5(EPHB4):c.1251G>A (p.Thr417=)
NM_004444.5(EPHB4):c.133C>G (p.Leu45Val)
NM_004444.5(EPHB4):c.1423-6G>A rs762817852
NM_004444.5(EPHB4):c.1609C>T (p.Gln537Ter) rs2116435260
NM_004444.5(EPHB4):c.1625C>T (p.Ala542Val)
NM_004444.5(EPHB4):c.175G>A (p.Glu59Lys) rs1584667224
NM_004444.5(EPHB4):c.187G>C (p.Val63Leu)
NM_004444.5(EPHB4):c.1961C>T (p.Thr654Met)
NM_004444.5(EPHB4):c.1990G>A (p.Glu664Lys) rs1562969219
NM_004444.5(EPHB4):c.2233A>G (p.Asn745Asp) rs1584654433
NM_004444.5(EPHB4):c.2257G>A (p.Val753Ile)
NM_004444.5(EPHB4):c.2277T>C (p.Phe759=)
NM_004444.5(EPHB4):c.242G>A (p.Arg81Gln)
NM_004444.5(EPHB4):c.2698G>C (p.Asp900His)
NM_004444.5(EPHB4):c.272G>A (p.Arg91His)
NM_004444.5(EPHB4):c.2784C>T (p.Phe928=)
NM_004444.5(EPHB4):c.2864C>T (p.Ala955Val)
NM_004444.5(EPHB4):c.319T>C (p.Cys107Arg) rs1562974383
NM_004444.5(EPHB4):c.366G>A (p.Thr122=) rs146092347
NM_004444.5(EPHB4):c.419C>T (p.Thr140Met)
NM_004444.5(EPHB4):c.428C>T (p.Ala143Val)
NM_004444.5(EPHB4):c.624G>A (p.Pro208=)
NM_004444.5(EPHB4):c.73T>C (p.Leu25=)
NM_004444.5(EPHB4):c.802T>C (p.Cys268Arg) rs201816920
NM_004444.5(EPHB4):c.896C>G (p.Ser299Ter) rs964985310
NM_004444.5(EPHB4):c.998G>A (p.Arg333His)

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