ClinVar Miner

Variants in gene FGFR3 with conflicting interpretations

Y axis minimum submission review status: Y axis collection method:
X axis minimum submission review status: X axis collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than two submissions, it may have multiple conflicts and therefore be counted in more than one conflict column. If this is the case, the "Variants with any kind of conflict" cell will be less than the sum of the conflicted variants cells to its left.

Variants with only 1 submission Variants with at least 2 submissions and no conflicts Variants with a synonymous conflict
(e.g. benign vs non-pathogenic)
Variants with a confidence conflict
(e.g. benign vs likely benign)
Variants with a benign or likely benign vs uncertain conflict Variants with a category conflict
(e.g. benign vs affects)
Variants with a clinically significant conflict
(e.g. benign vs pathogenic)
Variants with any kind of conflict
191 38 23 21 11 0 7 52

Significance breakdown #

In the table below, cells that correspond to a term paired with itself represent synonymous conflicts, i.e. variants that have been annotated with different terms that map to the same standard term. To compare the terms that were actually submitted, check the box in the filters section at the top of this page.

pathogenic likely pathogenic uncertain significance likely benign benign
pathogenic 23 8 5 0 0
likely pathogenic 8 0 4 0 0
uncertain significance 5 4 0 8 3
likely benign 0 0 8 0 13
benign 0 0 3 13 0

All variants with conflicting interpretations #

Total variants: 52
Download table as spreadsheet
HGVS dbSNP
NM_000142.4(FGFR3):c.1959+8C>T rs371666188
NM_001163213.1(FGFR3):c.1082-517C>G rs1057517964
NM_001163213.1(FGFR3):c.1082-545G>T rs587778775
NM_001163213.1(FGFR3):c.1082-546G>A
NM_001163213.1(FGFR3):c.1114G>T (p.Gly372Cys) rs121913479
NM_001163213.1(FGFR3):c.1117A>T (p.Ser373Cys) rs121913484
NM_001163213.1(FGFR3):c.1124A>G (p.Tyr375Cys) rs121913485
NM_001163213.1(FGFR3):c.1144G>A (p.Gly382Arg) rs28931614
NM_001163213.1(FGFR3):c.1156T>C (p.Phe386Leu) rs17881656
NM_001163213.1(FGFR3):c.1178C>A (p.Ala393Glu) rs28931615
NM_001163213.1(FGFR3):c.1229C>T (p.Ser410Phe) rs761877926
NM_001163213.1(FGFR3):c.1296C>T (p.Ser432=) rs3135891
NM_001163213.1(FGFR3):c.130G>A (p.Gly44Ser) rs146080119
NM_001163213.1(FGFR3):c.1351C>T (p.Pro451Ser) rs61735104
NM_001163213.1(FGFR3):c.1503C>T (p.Ala501=) rs140594137
NM_001163213.1(FGFR3):c.150C>T (p.Val50=) rs750641928
NM_001163213.1(FGFR3):c.1556A>G (p.Lys519Arg) rs139707740
NM_001163213.1(FGFR3):c.1618A>G (p.Ile540Val) rs80053154
NM_001163213.1(FGFR3):c.1625A>C (p.Asn542Thr) rs77722678
NM_001163213.1(FGFR3):c.1625A>G (p.Asn542Ser) rs77722678
NM_001163213.1(FGFR3):c.1626C>A (p.Asn542Lys) rs28933068
NM_001163213.1(FGFR3):c.1626C>G (p.Asn542Lys) rs28933068
NM_001163213.1(FGFR3):c.1663G>A (p.Val555Met) rs199544087
NM_001163213.1(FGFR3):c.169G>A (p.Val57Met) rs61735064
NM_001163213.1(FGFR3):c.1758G>A (p.Pro586=) rs139020690
NM_001163213.1(FGFR3):c.1885G>A (p.Glu629Lys) rs200849753
NM_001163213.1(FGFR3):c.188C>G (p.Pro63Arg) rs371729802
NM_001163213.1(FGFR3):c.1929C>T (p.Asp643=) rs148104605
NM_001163213.1(FGFR3):c.193G>A (p.Gly65Arg) rs2305178
NM_001163213.1(FGFR3):c.1954A>C (p.Lys652Gln) rs78311289
NM_001163213.1(FGFR3):c.1954A>G (p.Lys652Glu) rs78311289
NM_001163213.1(FGFR3):c.1955A>C (p.Lys652Thr) rs121913105
NM_001163213.1(FGFR3):c.1955A>T (p.Lys652Met) rs121913105
NM_001163213.1(FGFR3):c.1956G>T (p.Lys652Asn) rs28928868
NM_001163213.1(FGFR3):c.1959A>G (p.Thr653=) rs7688609
NM_001163213.1(FGFR3):c.2049G>A (p.Gly683=) rs17883356
NM_001163213.1(FGFR3):c.2094C>T (p.Pro698=) rs142884145
NM_001163213.1(FGFR3):c.2265C>T (p.Thr755=) rs146662137
NM_001163213.1(FGFR3):c.2425T>A (p.Ter809Arg) rs121913101
NM_001163213.1(FGFR3):c.2425T>G (p.Ter809Gly) rs121913101
NM_001163213.1(FGFR3):c.2426G>T (p.Ter809Leu) rs397515514
NM_001163213.1(FGFR3):c.2427A>G (p.Ter809Trp) rs121913103
NM_001163213.1(FGFR3):c.2427A>T (p.Ter809Cys) rs121913103
NM_001163213.1(FGFR3):c.251C>T (p.Ser84Leu) rs121913116
NM_001163213.1(FGFR3):c.252G>A (p.Ser84=) rs367973461
NM_001163213.1(FGFR3):c.272C>T (p.Pro91Leu) rs144995231
NM_001163213.1(FGFR3):c.393G>A (p.Ser131=) rs55662109
NM_001163213.1(FGFR3):c.598C>T (p.Arg200Cys) rs886043613
NM_001163213.1(FGFR3):c.666C>T (p.Asp222=) rs201081464
NM_001163213.1(FGFR3):c.742C>T (p.Arg248Cys) rs121913482
NM_001163213.1(FGFR3):c.746C>G (p.Ser249Cys) rs121913483
NM_001163213.1(FGFR3):c.833A>G (p.Tyr278Cys) rs121913115

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