ClinVar Miner

Variants in gene FLNC with conflicting interpretations

Y axis minimum submission review status: Y axis collection method:
X axis minimum submission review status: X axis collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than two submissions, it may have multiple conflicts and therefore be counted in more than one conflict column. If this is the case, the "Variants with any kind of conflict" cell will be less than the sum of the conflicted variants cells to its left.

Variants with only 1 submission per condition Variants with at least 2 submissions on the same condition and no conflicts Variants with a synonymous conflict
(e.g. benign vs non-pathogenic)
Variants with a confidence conflict
(e.g. benign vs likely benign)
Variants with a benign or likely benign vs uncertain conflict Variants with a category conflict
(e.g. benign vs affects)
Variants with a clinically significant conflict
(e.g. benign vs pathogenic)
Variants with any conflict
1925 85 0 19 14 0 2 35

Significance breakdown #

In the table below, cells that correspond to a term paired with itself represent synonymous conflicts, i.e. variants that have been annotated with different terms that map to the same standard term. To compare the terms that were actually submitted, check the box in the filters section at the top of this page.

pathogenic likely pathogenic uncertain significance likely benign benign
likely pathogenic 0 0 1 0 0
uncertain significance 1 1 0 13 1
likely benign 0 0 13 0 19
benign 0 0 1 19 0

All variants with conflicting interpretations #

Total variants: 35
Download table as spreadsheet
HGVS dbSNP
NM_001458.4(FLNC):c.-12G>T rs199842696
NM_001458.4(FLNC):c.1374C>T (p.Pro458=) rs115140972
NM_001458.4(FLNC):c.1614C>T (p.Tyr538=) rs76046880
NM_001458.4(FLNC):c.1632G>A (p.Lys544=) rs566538377
NM_001458.4(FLNC):c.1813+11G>T rs138716837
NM_001458.4(FLNC):c.2130C>T (p.Asp710=) rs778781499
NM_001458.4(FLNC):c.2266-14G>C rs75612085
NM_001458.4(FLNC):c.2390-8C>G rs146063718
NM_001458.4(FLNC):c.2390-9T>C rs368068407
NM_001458.4(FLNC):c.2501C>T (p.Thr834Met) rs75133741
NM_001458.4(FLNC):c.3006G>A (p.Arg1002=) rs61737781
NM_001458.4(FLNC):c.3054C>T (p.Gly1018=) rs769624093
NM_001458.4(FLNC):c.3838C>T (p.Leu1280=) rs34180031
NM_001458.4(FLNC):c.3938G>A (p.Arg1313Gln) rs199804244
NM_001458.4(FLNC):c.4022G>A (p.Arg1341Gln) rs149641783
NM_001458.4(FLNC):c.4161C>T (p.Ile1387=) rs200288149
NM_001458.4(FLNC):c.4947C>T (p.Gly1649=) rs201069454
NM_001458.4(FLNC):c.5020G>A (p.Gly1674Ser) rs374124083
NM_001458.4(FLNC):c.5042C>G (p.Thr1681Arg) rs193159707
NM_001458.4(FLNC):c.5544C>T (p.Ser1848=) rs1350503435
NM_001458.4(FLNC):c.5578C>T (p.Arg1860Cys) rs181067717
NM_001458.4(FLNC):c.5592C>T (p.Ala1864=) rs117517372
NM_001458.4(FLNC):c.5644A>G (p.Ile1882Val) rs184018403
NM_001458.4(FLNC):c.577G>A (p.Ala193Thr) rs387906587
NM_001458.4(FLNC):c.597C>T (p.Ala199=) rs143942649
NM_001458.4(FLNC):c.6175G>A (p.Val2059Met) rs201333104
NM_001458.4(FLNC):c.6441C>T (p.Ile2147=) rs762017885
NM_001458.4(FLNC):c.6771A>G (p.Pro2257=) rs34422412
NM_001458.4(FLNC):c.6998-5C>T rs139030003
NM_001458.4(FLNC):c.7780+10A>G rs201149834
NM_001458.4(FLNC):c.7862G>A (p.Arg2621Gln) rs201636548
NM_001458.4(FLNC):c.8003T>C (p.Met2668Thr) rs200502811
NM_001458.4(FLNC):c.8118C>T (p.Leu2706=) rs28379666
NM_001458.4(FLNC):c.8121T>C (p.Ile2707=) rs28437296
Single allele

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