ClinVar Miner

Variants in gene FRAS1 with conflicting interpretations

Y axis minimum submission review status: Y axis collection method:
X axis minimum submission review status: X axis collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than two submissions, it may have multiple conflicts and therefore be counted in more than one conflict column. If this is the case, the "Variants with any kind of conflict" cell will be less than the sum of the conflicted variants cells to its left.

Variants with only 1 submission per condition Variants with at least 2 submissions on the same condition and no conflicts Variants with a synonymous conflict
(e.g. benign vs non-pathogenic)
Variants with a confidence conflict
(e.g. benign vs likely benign)
Variants with a benign or likely benign vs uncertain conflict Variants with a category conflict
(e.g. benign vs affects)
Variants with a clinically significant conflict
(e.g. benign vs pathogenic)
Variants with any conflict
598 42 0 16 19 0 1 36

Significance breakdown #

In the table below, cells that correspond to a term paired with itself represent synonymous conflicts, i.e. variants that have been annotated with different terms that map to the same standard term. To compare the terms that were actually submitted, check the box in the filters section at the top of this page.

pathogenic likely pathogenic uncertain significance likely benign benign
pathogenic 0 1 1 0 0
likely pathogenic 1 0 0 0 0
uncertain significance 1 0 0 14 5
likely benign 0 0 14 0 15
benign 0 0 5 15 0

All variants with conflicting interpretations #

Total variants: 36
Download table as spreadsheet
NM_025074.7(FRAS1):c.10237C>T (p.Pro3413Ser) rs189612722
NM_025074.7(FRAS1):c.10539A>G (p.Thr3513=) rs199921300
NM_025074.7(FRAS1):c.10594A>G (p.Ile3532Val) rs144715071
NM_025074.7(FRAS1):c.108+10T>G rs76831011
NM_025074.7(FRAS1):c.109-15del rs548267943
NM_025074.7(FRAS1):c.11605A>G (p.Ile3869Val) rs145035489
NM_025074.7(FRAS1):c.11717T>C (p.Ile3906Thr) rs61748814
NM_025074.7(FRAS1):c.11907C>G (p.His3969Gln) rs140492803
NM_025074.7(FRAS1):c.1635C>T (p.Ser545=) rs528765554
NM_025074.7(FRAS1):c.1769T>C (p.Met590Thr) rs35030041
NM_025074.7(FRAS1):c.2862G>A (p.Thr954=) rs144065807
NM_025074.7(FRAS1):c.2956G>A (p.Ala986Thr) rs111554790
NM_025074.7(FRAS1):c.3058C>T (p.Arg1020Cys) rs200292361
NM_025074.7(FRAS1):c.39G>A (p.Ala13=) rs773457837
NM_025074.7(FRAS1):c.4095C>T (p.Ile1365=) rs79869130
NM_025074.7(FRAS1):c.4308+10G>T rs146718957
NM_025074.7(FRAS1):c.4579C>T (p.Arg1527Trp) rs1872267
NM_025074.7(FRAS1):c.4648C>T (p.Leu1550Phe) rs148663672
NM_025074.7(FRAS1):c.4958C>T (p.Pro1653Leu) rs6813102
NM_025074.7(FRAS1):c.5046C>G (p.Asp1682Glu) rs35219594
NM_025074.7(FRAS1):c.5125C>T (p.Arg1709Ter) rs775517752
NM_025074.7(FRAS1):c.5374G>A (p.Ala1792Thr) rs150916370
NM_025074.7(FRAS1):c.5419_5424del (p.Phe1807_Ser1808del) rs730882178
NM_025074.7(FRAS1):c.641C>T (p.Pro214Leu) rs200053639
NM_025074.7(FRAS1):c.6939C>T (p.Pro2313=) rs150936204
NM_025074.7(FRAS1):c.7029+7G>A rs183687186
NM_025074.7(FRAS1):c.7033G>A (p.Glu2345Lys) rs56291926
NM_025074.7(FRAS1):c.7622A>G (p.Asn2541Ser) rs144530996
NM_025074.7(FRAS1):c.776T>G (p.Leu259Arg) rs148509395
NM_025074.7(FRAS1):c.8574G>A (p.Lys2858=) rs201745281
NM_025074.7(FRAS1):c.8832C>T (p.Ser2944=) rs114854941
NM_025074.7(FRAS1):c.9627C>T (p.Tyr3209=) rs377369857
NM_025074.7(FRAS1):c.969G>A (p.Val323=) rs377333036
NM_025074.7(FRAS1):c.9806G>A (p.Arg3269Gln) rs61729366
NM_025074.7(FRAS1):c.9853C>T (p.His3285Tyr) rs182196851
NM_025074.7(FRAS1):c.990A>G (p.Glu330=) rs374045395

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