ClinVar Miner

Variants in gene FRAS1 with conflicting interpretations

Y axis minimum submission review status: Y axis collection method:
X axis minimum submission review status: X axis collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than two submissions, it may have multiple conflicts and therefore be counted in more than one conflict column. If this is the case, the "Variants with any kind of conflict" cell will be less than the sum of the conflicted variants cells to its left.

Variants with only 1 submission Variants with at least 2 submissions and no conflicts Variants with a synonymous conflict
(e.g. benign vs non-pathogenic)
Variants with a confidence conflict
(e.g. benign vs likely benign)
Variants with a benign or likely benign vs uncertain conflict Variants with a category conflict
(e.g. benign vs affects)
Variants with a clinically significant conflict
(e.g. benign vs pathogenic)
Variants with any kind of conflict
331 40 0 14 11 1 2 25

Significance breakdown #

In the table below, cells that correspond to a term paired with itself represent synonymous conflicts, i.e. variants that have been annotated with different terms that map to the same standard term. To compare the terms that were actually submitted, check the box in the filters section at the top of this page.

pathogenic likely pathogenic uncertain significance likely benign benign risk factor
pathogenic 0 1 2 0 0 0
likely pathogenic 1 0 0 0 0 0
uncertain significance 2 0 0 5 8 1
likely benign 0 0 5 0 13 1
benign 0 0 8 13 0 1
risk factor 0 0 1 1 1 0

All variants with conflicting interpretations #

Total variants: 25
Download table as spreadsheet
NM_025074.7(FRAS1):c.10153T>G (p.Tyr3385Asp) rs35933858
NM_025074.7(FRAS1):c.10389+11C>T rs74632598
NM_025074.7(FRAS1):c.10539A>G (p.Thr3513=) rs199921300
NM_025074.7(FRAS1):c.10594A>G (p.Ile3532Val) rs144715071
NM_025074.7(FRAS1):c.10683A>T (p.Glu3561Asp) rs931605
NM_025074.7(FRAS1):c.109-15del rs548267943
NM_025074.7(FRAS1):c.11605A>G (p.Ile3869Val) rs145035489
NM_025074.7(FRAS1):c.11718T>C (p.Ile3906=) rs142389362
NM_025074.7(FRAS1):c.11724T>C (p.Ser3908=) rs151307846
NM_025074.7(FRAS1):c.11907C>G (p.His3969Gln) rs140492803
NM_025074.7(FRAS1):c.1635C>T (p.Ser545=) rs528765554
NM_025074.7(FRAS1):c.2719C>T (p.Gln907Ter) rs755750961
NM_025074.7(FRAS1):c.3058C>T (p.Arg1020Cys) rs200292361
NM_025074.7(FRAS1):c.3068G>A (p.Gly1023Glu) rs17459809
NM_025074.7(FRAS1):c.3124G>A (p.Ala1042Thr) rs114077522
NM_025074.7(FRAS1):c.3312T>C (p.Ser1104=) rs35774552
NM_025074.7(FRAS1):c.4635G>A (p.Pro1545=) rs78575519
NM_025074.7(FRAS1):c.5046C>G (p.Asp1682Glu) rs35219594
NM_025074.7(FRAS1):c.5419_5424del (p.Phe1807_Ser1808del) rs730882178
NM_025074.7(FRAS1):c.6924C>T (p.Val2308=) rs13123710
NM_025074.7(FRAS1):c.7551T>A (p.Tyr2517Ter) rs745597204
NM_025074.7(FRAS1):c.776T>G (p.Leu259Arg) rs148509395
NM_025074.7(FRAS1):c.9252G>T (p.Arg3084=) rs11933630
NM_025074.7(FRAS1):c.9364C>T (p.Arg3122Trp) rs200346497
NM_025074.7(FRAS1):c.9806G>A (p.Arg3269Gln) rs61729366

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