ClinVar Miner

Variants in gene GCK with conflicting interpretations

Y axis minimum submission review status: Y axis collection method:
X axis minimum submission review status: X axis collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than two submissions, it may have multiple conflicts and therefore be counted in more than one conflict column. If this is the case, the "Variants with any kind of conflict" cell will be less than the sum of the conflicted variants cells to its left.

Variants with only 1 submission Variants with at least 2 submissions and no conflicts Variants with a synonymous conflict
(e.g. benign vs non-pathogenic)
Variants with a confidence conflict
(e.g. benign vs likely benign)
Variants with a benign or likely benign vs uncertain conflict Variants with a category conflict
(e.g. benign vs affects)
Variants with a clinically significant conflict
(e.g. benign vs pathogenic)
Variants with any kind of conflict
245 52 5 25 3 0 11 42

Significance breakdown #

In the table below, cells that correspond to a term paired with itself represent synonymous conflicts, i.e. variants that have been annotated with different terms that map to the same standard term. To compare the terms that were actually submitted, check the box in the filters section at the top of this page.

pathogenic likely pathogenic uncertain significance likely benign benign
pathogenic 3 10 0 0 0
likely pathogenic 10 0 11 0 0
uncertain significance 0 11 2 3 1
likely benign 0 0 3 0 15
benign 0 0 1 15 0

All variants with conflicting interpretations #

Total variants: 42
Download table as spreadsheet
HGVS dbSNP
NM_000162.3(GCK):c.1003delG (p.Val335Cysfs) rs193922254
NM_000162.3(GCK):c.1019+18G>A rs150914617
NM_000162.3(GCK):c.1019+2T>G rs193929376
NM_000162.3(GCK):c.1020-10C>A rs193922257
NM_000162.3(GCK):c.106C>T (p.Arg36Trp) rs762263694
NM_000162.3(GCK):c.1130G>A (p.Arg377His) rs193922264
NM_000162.3(GCK):c.1130_1138delGCGCTGCGC (p.Arg377_Ala379del) rs1131691505
NM_000162.3(GCK):c.1136C>A (p.Ala379Glu) rs193922265
NM_000162.3(GCK):c.113A>C (p.Gln38Pro) rs1064794268
NM_000162.3(GCK):c.1190G>T (p.Arg397Leu) rs193929375
NM_000162.3(GCK):c.1253+8C>T rs2908274
NM_000162.3(GCK):c.1288C>T (p.Leu430=) rs193922276
NM_000162.3(GCK):c.1322C>T (p.Ser441Leu) rs1286804191
NM_000162.3(GCK):c.146C>A (p.Thr49Asn) rs193922286
NM_000162.3(GCK):c.175C>T (p.Pro59Ser) rs193922287
NM_000162.3(GCK):c.208+11G>A rs77440690
NM_000162.3(GCK):c.209-8G>A rs144798843
NM_000162.3(GCK):c.333C>T (p.Pro111=) rs61736250
NM_000162.3(GCK):c.339C>T (p.Asp113=) rs149412035
NM_000162.3(GCK):c.363+10G>A rs758495950
NM_000162.3(GCK):c.364-1G>A rs1057521094
NM_000162.3(GCK):c.364C>A (p.Leu122Ile) rs1554335616
NM_000162.3(GCK):c.370G>A (p.Asp124Asn) rs759072800
NM_000162.3(GCK):c.449T>C (p.Phe150Ser) rs193922297
NM_000162.3(GCK):c.46-12C>T rs142829768
NM_000162.3(GCK):c.616A>C (p.Thr206Pro) rs587780346
NM_000162.3(GCK):c.618G>A (p.Thr206=) rs142817246
NM_000162.3(GCK):c.629T>A (p.Met210Lys) rs80356654
NM_000162.3(GCK):c.645C>T (p.Tyr215=) rs144723656
NM_000162.3(GCK):c.661G>A (p.Glu221Lys) rs193922317
NM_000162.3(GCK):c.666C>T (p.Val222=) rs193922318
NM_000162.3(GCK):c.683C>T (p.Thr228Met) rs80356655
NM_000162.3(GCK):c.748C>T (p.Arg250Cys) rs1057524904
NM_000162.3(GCK):c.76C>T (p.Gln26Ter) rs193922329
NM_000162.3(GCK):c.863+3A>G rs193922334
NM_000162.3(GCK):c.954G>C (p.Gly318=) rs145764627
NM_000162.4(GCK):c.31G>A (p.Ala11Thr) rs116093166
NM_000162.4(GCK):c.364-18A>G rs191255582
NM_000162.4(GCK):c.483+14A>G rs74852379
NM_000162.4(GCK):c.572G>A (p.Arg191Gln) rs886042610
NM_000162.4(GCK):c.660C>T (p.Cys220=) rs142952813
NM_000162.5(GCK):c.676G>A (p.Val226Met) rs148311934

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