ClinVar Miner

Variants in gene GRIN1 with conflicting interpretations

Y axis minimum submission review status: Y axis collection method:
X axis minimum submission review status: X axis collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than two submissions, it may have multiple conflicts and therefore be counted in more than one conflict column. If this is the case, the "Variants with any kind of conflict" cell will be less than the sum of the conflicted variants cells to its left.

Variants with only 1 submission per condition Variants with at least 2 submissions on the same condition and no conflicts Variants with a synonymous conflict
(e.g. benign vs non-pathogenic)
Variants with a confidence conflict
(e.g. benign vs likely benign)
Variants with a benign or likely benign vs uncertain conflict Variants with a category conflict
(e.g. benign vs affects)
Variants with a clinically significant conflict
(e.g. benign vs pathogenic)
Variants with any conflict
345 13 0 15 6 1 6 24

Significance breakdown #

In the table below, cells that correspond to a term paired with itself represent synonymous conflicts, i.e. variants that have been annotated with different terms that map to the same standard term. To compare the terms that were actually submitted, check the box in the filters section at the top of this page.

pathogenic likely pathogenic uncertain significance likely benign benign drug response protective other
pathogenic 0 3 1 0 0 0 0 0
likely pathogenic 3 0 4 0 0 0 0 0
uncertain significance 2 5 0 6 3 1 1 1
likely benign 0 0 5 0 12 0 0 0
benign 0 0 2 12 0 0 0 0

All variants with conflicting interpretations #

Total variants: 24
Download table as spreadsheet
NM_007327.4(GRIN1):c.1005T>C (p.Thr335=) rs145176345
NM_007327.4(GRIN1):c.1044C>T (p.Phe348=) rs143483243
NM_007327.4(GRIN1):c.1467+8G>A rs10747050
NM_007327.4(GRIN1):c.1584G>A (p.Glu528=) rs116006955
NM_007327.4(GRIN1):c.1809G>C (p.Leu603=) rs141249927
NM_007327.4(GRIN1):c.1858G>A (p.Gly620Arg) rs797045047
NM_007327.4(GRIN1):c.1858G>C (p.Gly620Arg) rs797045047
NM_007327.4(GRIN1):c.1974C>G (p.Asp658Glu) rs1064795712
NM_007327.4(GRIN1):c.2223G>C (p.Ser741=) rs767848286
NM_007327.4(GRIN1):c.2241G>C (p.Val747=) rs116354349
NM_007327.4(GRIN1):c.2244G>C (p.Thr748=) rs79570612
NM_007327.4(GRIN1):c.2328C>T (p.Ile776=) rs200088954
NM_007327.4(GRIN1):c.2444G>A (p.Gly815Glu)
NM_007327.4(GRIN1):c.2479G>A (p.Gly827Arg) rs1451230055
NM_007327.4(GRIN1):c.2499C>T (p.Ile833=) rs146086141
NM_007327.4(GRIN1):c.2500G>C (p.Glu834Gln) rs1588735834
NM_007327.4(GRIN1):c.2530C>T (p.Arg844Cys) rs1554770667
NM_007327.4(GRIN1):c.448G>A (p.Val150Met)
NM_007327.4(GRIN1):c.525G>A (p.Ala175=) rs77812749
NM_007327.4(GRIN1):c.705C>T (p.Ala235=) rs201343933
NM_007327.4(GRIN1):c.768G>C (p.Gly256=) rs141473515
NM_007327.4(GRIN1):c.789A>G (p.Pro263=) rs6293
NM_007327.4(GRIN1):c.855G>A (p.Val285=) rs1126442
Single allele

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