ClinVar Miner

Variants in gene GRM1 with conflicting interpretations

Y axis minimum submission review status: Y axis collection method:
X axis minimum submission review status: X axis collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than two submissions, it may have multiple conflicts and therefore be counted in more than one conflict column. If this is the case, the "Variants with any kind of conflict" cell will be less than the sum of the conflicted variants cells to its left.

Variants with only 1 submission per condition Variants with at least 2 submissions on the same condition and no conflicts Variants with a synonymous conflict
(e.g. benign vs non-pathogenic)
Variants with a confidence conflict
(e.g. benign vs likely benign)
Variants with a benign or likely benign vs uncertain conflict Variants with a category conflict
(e.g. benign vs affects)
Variants with a clinically significant conflict
(e.g. benign vs pathogenic)
Variants with any conflict
99 16 0 12 1 0 0 13

Significance breakdown #

In the table below, cells that correspond to a term paired with itself represent synonymous conflicts, i.e. variants that have been annotated with different terms that map to the same standard term. To compare the terms that were actually submitted, check the box in the filters section at the top of this page.

uncertain significance likely benign benign
uncertain significance 0 1 0
likely benign 1 0 12
benign 0 12 0

All variants with conflicting interpretations #

Total variants: 13
Download table as spreadsheet
HGVS dbSNP
NM_001278064.2(GRM1):c.1433+10T>C rs373538200
NM_001278064.2(GRM1):c.2026G>A (p.Val676Met) rs752403373
NM_001278064.2(GRM1):c.2793G>A (p.Lys931=) rs2942
NM_001278064.2(GRM1):c.2859C>T (p.Thr953=) rs116471335
NM_001278064.2(GRM1):c.2922T>C (p.Pro974=) rs142409803
NM_001278064.2(GRM1):c.2977T>C (p.Ser993Pro) rs6923492
NM_001278064.2(GRM1):c.3161G>A (p.Gly1054Asp) rs145764886
NM_001278064.2(GRM1):c.3168T>G (p.Gly1056=) rs6923864
NM_001278064.2(GRM1):c.3206C>T (p.Pro1069Leu) rs79336287
NM_001278064.2(GRM1):c.3214C>G (p.Pro1072Ala) rs146753539
NM_001278064.2(GRM1):c.3495C>A (p.Pro1165=) rs9373491
NM_001278064.2(GRM1):c.444C>G (p.Pro148=) rs138794480
NM_001278064.2(GRM1):c.922G>A (p.Val308Ile) rs112915383

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